7Z39
Structure of Belumosudil bound to CK2alpha
Summary for 7Z39
| Entry DOI | 10.2210/pdb7z39/pdb |
| Descriptor | Casein kinase II subunit alpha, ACETATE ION, 2-[3-[4-(1~{H}-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-~{N}-propan-2-yl-ethanamide, ... (5 entities in total) |
| Functional Keywords | kinase selectivity, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 39815.05 |
| Authors | Brear, P.,Hyvonen, M. (deposition date: 2022-03-01, release date: 2022-10-12, Last modification date: 2024-02-07) |
| Primary citation | Brear, P.,Hyvonen, M. Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2 alpha. Acta Crystallogr.,Sect.F, 78:348-353, 2022 Cited by PubMed: 36189718DOI: 10.1107/S2053230X22008767 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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