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6EUW
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BU of 6euw by Molmil
Crystal structure of the cap-binding domain of the PB2 subunit of influenza A/H5N1 polymerase bound to an azaindazole inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, GLYCEROL, Polymerase basic protein 2
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6XIJ
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BU of 6xij by Molmil
Escherichia coli transcription-translation complex A (TTC-A) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-06-20
Release date:2020-09-02
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
9UHT
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BU of 9uht by Molmil
SARS-CoV-2 E-RTC in complex with RNA-nsp9 and GMPPNP
Descriptor: Helicase nsp13, Non-structural protein 7, Non-structural protein 8, ...
Authors:Huang, Y.C, Liu, Y.X, Lou, Z.Y, Rao, Z.H, Yan, L.M.
Deposit date:2025-04-14
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Response to Matter Arising: Substrate selection and transition state support the mechanism for GTP-mediate RNA capping catalyzed by SARS-CoV-2 NiRAN
To Be Published
8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
4D2G
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BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
8Y0X
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BU of 8y0x by Molmil
Dormant ribosome with SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Du, M, Zeng, F.
Deposit date:2024-01-23
Release date:2024-02-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
6VZ5
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BU of 6vz5 by Molmil
Escherichia coli transcription-translation complex D3 (TTC-D3) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYZ
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BU of 6vyz by Molmil
Escherichia coli transcription-translation complex C6 (TTC-C6) containing mRNA with a 21 nt long spacer, NusA, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYU
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BU of 6vyu by Molmil
Escherichia coli transcription-translation complex C2 (TTC-C2) containing a 27 nt long mRNA spacer
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VZ2
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BU of 6vz2 by Molmil
Escherichia coli transcription-translation complex D1 (TTC-D1) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYY
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BU of 6vyy by Molmil
Escherichia coli transcription-translation complex C5 (TTC-C5) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYW
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BU of 6vyw by Molmil
Escherichia coli transcription-translation complex C3 (TTC-C3) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYX
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BU of 6vyx by Molmil
Escherichia coli transcription-translation complex C4 (TTC-C4) containing mRNA with a 21 nt long spacer, transcription factor NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VZ7
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BU of 6vz7 by Molmil
Escherichia coli transcription-translation complex C1 (TTC-C1) containing a 27 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2025-03-19
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VZJ
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BU of 6vzj by Molmil
Escherichia coli transcription-translation complex A1 (TTC-A1) containing mRNA with a 15 nt long spacer, fMet-tRNAs at E-site and P-site, and lacking transcription factor NusG
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-28
Release date:2020-09-02
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYR
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BU of 6vyr by Molmil
Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 18 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
9G8M
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BU of 9g8m by Molmil
human 80S ribosome bound by a SKI2-exosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E.
Deposit date:2024-07-23
Release date:2024-10-23
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of mRNA decay by the human exosome-ribosome supercomplex.
Nature, 635, 2024
6VYQ
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BU of 6vyq by Molmil
Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 15 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VYT
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BU of 6vyt by Molmil
Escherichia coli transcription-translation complex A2 (TTC-A2) containing a 15 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H, Su, M.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
3JTG
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BU of 3jtg by Molmil
Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA
Descriptor: DNA (5'-D(*CP*AP*AP*AP*CP*AP*GP*GP*AP*AP*AP*CP*TP*CP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*GP*TP*TP*TP*CP*CP*TP*GP*TP*TP*T)-3'), ETS-related transcription factor Elf-3
Authors:Tahirov, T.H, Babayeva, N.D, Agarkar, V.B, Rizzino, A.
Deposit date:2009-09-11
Release date:2010-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA.
J.Mol.Biol., 397, 2010
6VYS
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BU of 6vys by Molmil
Escherichia coli transcription-translation complex A1 (TTC-A1) containing a 21 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6VU3
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BU of 6vu3 by Molmil
Cryo-EM structure of Escherichia coli transcription-translation complex A (TTC-A) containing mRNA with a 12 nt long spacer
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.
Deposit date:2020-02-14
Release date:2020-09-02
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6FBI
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BU of 6fbi by Molmil
KlenTaq DNA polymerase in a closed, ternary complex with dGpNHpp bound in the active site
Descriptor: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Kropp, H.M, Diederichs, K, Marx, A.
Deposit date:2017-12-19
Release date:2018-09-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Snapshots of a modified nucleotide moving through the confines of a DNA polymerase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6VZ3
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BU of 6vz3 by Molmil
Escherichia coli transcription-translation complex D2 (TTC-D2) containing mRNA with a 27 nt long spacer
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-02-27
Release date:2020-09-02
Last modified:2025-02-19
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
9G8O
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BU of 9g8o by Molmil
human 40S ribosome bound by a SKI238-exosome complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Koegel, A, Keidel, A, Loukeri, M.J, Kuhn, C.C, Langer, L.M, Schaefer, I.B, Conti, E.
Deposit date:2024-07-23
Release date:2024-10-16
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of mRNA decay by the human exosome-ribosome supercomplex.
Nature, 635, 2024

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