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1YID
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BU of 1yid by Molmil
Crystal structure of tryptophanyl tRNA synthetase II from Deinococcus radiodurans in complex with ATP.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tryptophanyl-tRNA synthetase
Authors:Buddha, M.R, Crane, B.R.
Deposit date:2005-01-11
Release date:2005-08-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of tryptophanyl-tRNA synthetase II from Deinococcus radiodurans bound to ATP and tryptophan. Insight into subunit cooperativity and domain motions linked to catalysis
J.Biol.Chem., 280, 2005
1WKS
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BU of 1wks by Molmil
Solution structure of an RNA stem-loop derived from the 3' conserved region of eel LINE UnaL2
Descriptor: 5'-R(*GP*GP*CP*UP*UP*UP*GP*GP*AP*UP*AP*AP*AP*AP*GP*CP*C)-3'
Authors:Baba, S, Kajikawa, M, Okada, N, Kawai, G.
Deposit date:2004-06-04
Release date:2004-06-22
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of an RNA stem-loop derived from the 3' conserved region of eel LINE UnaL2
Rna, 10, 2004
1RAW
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BU of 1raw by Molmil
ATP BINDING RNA APTAMER IN COMPLEX WITH AMP, NMR, 10 STRUCTURES
Descriptor: ADENOSINE MONOPHOSPHATE, RNA APTAMER
Authors:Dieckmann, T, Feigon, J.
Deposit date:1996-07-17
Release date:1997-01-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of an ATP-Binding RNA Aptamer Reveals a Novel Fold
RNA, 2, 1996
5EKT
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BU of 5ekt by Molmil
Crystal structure of mutant-K146A of peptidyl-tRNA hydrolase from Vibrio cholerae at 1.63A resolution.
Descriptor: CITRATE ANION, Peptidyl-tRNA hydrolase
Authors:Shahid, S, Kabr, A, Pal, R.K, Arora, A.
Deposit date:2015-11-04
Release date:2016-11-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structure of mutant-K146A of peptidyl-tRNA hydrolase from Vibrio cholerae at 1.63A resolution.
To be published
6MES
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BU of 6mes by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1907)
Descriptor: 1-[(1H-benzimidazol-2-yl)methyl]-4-[(2,4-dichlorophenyl)methyl]-1,3-dihydro-2H-imidazol-2-one, GLYCEROL, METHIONINE, ...
Authors:Barros-Alvarez, X, Hol, W.G.J.
Deposit date:2018-09-07
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei
Rsc Med Chem, 2020
6SJC
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BU of 6sjc by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine
Descriptor: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2019-08-13
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
5E3I
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BU of 5e3i by Molmil
Crystal Structure of a Histidyl-tRNA synthetase from Acinetobacter baumannii with bound L-Histidine and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HISTIDINE, Histidine--tRNA ligase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-10-02
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Histidyl-tRNA synthetase from Acinetobacter baumannii with bound L-Histidine and ATP
to be published
6NAB
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BU of 6nab by Molmil
Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with proline and adenosine monophophsphate (AMP)
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-05
Release date:2019-01-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with proline and adenosine monophophsphate (AMP)
TO BE PUBLISHED
5GVZ
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BU of 5gvz by Molmil
Crystal structure of Peptidyl-tRNA hydrolase from Vibrio cholerae in space group C2221 at resolution 1.75A.
Descriptor: ACETATE ION, Peptidyl-tRNA hydrolase, SULFATE ION
Authors:Shahid, S, Kabra, A, Pal, R.K, Arora, A.
Deposit date:2016-09-07
Release date:2017-09-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of Peptidyl-tRNA hydrolase from Vibrio cholerae in space group C2221 at resolution 1.75A.
To Be Published
8TC8
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BU of 8tc8 by Molmil
Human asparaginyl-tRNA synthetase bound to adenosine 5'-sulfamate
Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2023-06-30
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
4B9X
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BU of 4b9x by Molmil
Structure of extended Tudor domain TD3 from mouse TDRD1
Descriptor: TUDOR DOMAIN-CONTAINING PROTEIN 1
Authors:Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
Deposit date:2012-09-08
Release date:2012-10-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Multiple Tudor Domain-Containing Protein Tdrd1 is a Molecular Scaffold for Mouse Piwi Proteins and Pirna Biogenesis Factors.
RNA, 18, 2012
8U2P
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BU of 8u2p by Molmil
Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound)
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-06
Release date:2023-09-13
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound)
To be published
5F9Y
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BU of 5f9y by Molmil
Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Proline and AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Aminoacyl-tRNA synthetase, PHOSPHATE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-12-10
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Proline and AMP
to be published
4B9W
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BU of 4b9w by Molmil
Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45.
Descriptor: GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1
Authors:Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
Deposit date:2012-09-08
Release date:2012-10-17
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Rna, 18, 2012
7QB7
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BU of 7qb7 by Molmil
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT345 and L-Proline
Descriptor: 1,2-ETHANEDIOL, PROLINE, Proline--tRNA ligase, ...
Authors:Johansson, C, Tye, M, Payne, N.C, Mazitschek, R, Oppermann, U.C.T.
Deposit date:2021-11-18
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT345
To Be Published
5F9Z
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BU of 5f9z by Molmil
Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with Halofuginone and AMPPNP
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Aminoacyl-tRNA synthetase, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-12-10
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with Halofuginone and AMPPNP
to be published
5A34
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BU of 5a34 by Molmil
The crystal structure of the GST-like domains complex of EPRS-AIMP2
Descriptor: AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2, BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE, GLYCEROL
Authors:Cho, H.Y, Kang, B.S.
Deposit date:2015-05-27
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains.
J.Biol.Chem., 290, 2015
6HHW
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BU of 6hhw by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine
Descriptor: 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine, Aspartate--tRNA(Asp) ligase
Authors:De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-29
Release date:2019-12-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
7Y52
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BU of 7y52 by Molmil
Crystal structure of peptidyl-tRNA hydrolase from Enterococcus faecium
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Peptidyl-tRNA hydrolase, ...
Authors:Pandey, R, Zohib, M, Mundra, S, Pal, R.K, Arora, A.
Deposit date:2022-06-16
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Enterococcus faecium
To Be Published
8U2Q
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BU of 8u2q by Molmil
Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound)
Descriptor: 1,2-ETHANEDIOL, 5'-O-(glycylsulfamoyl)adenosine, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-06
Release date:2023-09-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound)
To be published
6J93
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BU of 6j93 by Molmil
Crystal structure of Peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.95 A resolution
Descriptor: 1,2-ETHANEDIOL, Peptidyl-tRNA hydrolase
Authors:Viswanathan, V, Sharma, P, Singh, P.K, Iqbal, N, Sharma, S, Singh, T.P.
Deposit date:2019-01-21
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Crystal structure of Peptidyl-tRNA hydrolase form apo at 0.95 A resolution.
To Be Published
7PQK
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BU of 7pqk by Molmil
Co-Crystal Structure of M. tuberculosis LeuRS in Complex with the Adduct Formed by Prodrug Cmpd1 with Adenosine-monophosphate
Descriptor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol, 1,2-ETHANEDIOL, Leucine--tRNA ligase
Authors:Palencia, A, Cusack, S.
Deposit date:2021-09-17
Release date:2023-01-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase.
J.Am.Chem.Soc., 145, 2023
7QC1
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BU of 7qc1 by Molmil
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT436
Descriptor: 1,2-ETHANEDIOL, Proline--tRNA ligase, [(2~{R},3~{S})-2-[3-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanylidene-propyl]piperidin-3-yl] ~{N}-[4-[[3-(2,3-dihydro-1~{H}-inden-2-ylcarbamoyl)pyrazin-2-yl]carbamoyl]piperazin-1-yl]sulfonylcarbamate
Authors:Johansson, C, Tye, M, Payne, N.C, Mazitschek, R, Oppermann, U.C.T.
Deposit date:2021-11-22
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT436
To Be Published
7QC2
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BU of 7qc2 by Molmil
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT334 and L-Proline
Descriptor: 1,2-ETHANEDIOL, PROLINE, Proline--tRNA ligase, ...
Authors:Johansson, C, Tye, M, Payne, N.C, Mazitschek, R, Oppermann, U.C.T.
Deposit date:2021-11-22
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT334 and L-Proline
To Be Published
8IU6
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BU of 8iu6 by Molmil
Crystal structure of peptidyl-tRNA hydrolase mutant from Enterococcus faecium
Descriptor: GLYCEROL, Peptidyl-tRNA hydrolase
Authors:Pandey, R, Tripathi, S, Lanka, A.K, Zohib, M, Pal, R.K, Arora, A.
Deposit date:2023-03-23
Release date:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase mutant from Enterococcus faecium
To Be Published

222415

PDB entries from 2024-07-10

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