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1YDE
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Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3
Descriptor: Retinal dehydrogenase/reductase 3
Authors:Lukacik, P, Bunkozci, G, Kavanagh, K, Sundstrom, M, Arrowsmith, C, Edwards, A, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2004-12-23
Release date:2005-01-18
Last modified:2012-03-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.
Biochem.J., 402, 2007
2OZ7
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BU of 2oz7 by Molmil
Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with cyproterone acetate
Descriptor: Androgen receptor, CYPROTERONE ACETATE
Authors:Bohl, C.E, Wu, Z, Miller, D.D, Bell, C.E, Dalton, J.T.
Deposit date:2007-02-25
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design.
J.Biol.Chem., 282, 2007
1ZFO
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BU of 1zfo by Molmil
AMINO-TERMINAL LIM-DOMAIN PEPTIDE OF LASP-1, NMR
Descriptor: LASP-1, ZINC ION
Authors:Hammarstrom, A, Berndt, K.D, Sillard, R, Adermann, K, Otting, G.
Deposit date:1996-05-06
Release date:1996-11-08
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of a naturally-occurring zinc-peptide complex demonstrates that the N-terminal zinc-binding module of the Lasp-1 LIM domain is an independent folding unit.
Biochemistry, 35, 1996
2OMW
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BU of 2omw by Molmil
Crystal structure of InlA S192N Y369S/mEC1 complex
Descriptor: CHLORIDE ION, Epithelial-cadherin, Internalin-A
Authors:Wollert, T, Heinz, D.W, Schubert, W.D.
Deposit date:2007-01-23
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Extending the host range of Listeria monocytogenes by rational protein design.
Cell(Cambridge,Mass.), 129, 2007
2AXN
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BU of 2axn by Molmil
Crystal structure of the human inducible form 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Descriptor: 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)], ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kim, S.G, Manes, N.P, El-Maghrabi, M.R, Lee, Y.H.
Deposit date:2005-09-05
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy.
J.Biol.Chem., 281, 2006
3IAL
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BU of 3ial by Molmil
Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate
Descriptor: 5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, GLYCEROL, Prolyl-tRNA synthetase
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-14
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia.
Acta Crystallogr.,Sect.D, 68, 2012
3J5S
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BU of 3j5s by Molmil
EttA binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S7, ...
Authors:Hashem, Y.
Deposit date:2013-11-15
Release date:2014-01-08
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics.
Nat.Struct.Mol.Biol., 21, 2014
3ZV6
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CRYSTAL STRUCTURE OF CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE (BPHB) FROM PANDORAEA PNOMENUSA STRAIN B-356 COMPLEX WITH CO-ENZYME NAD AND PRODUCT ANALOG 4,4'-DIHYDROXYBIPHENYL
Descriptor: 4,4'-DIHYDROXYBIPHENYL, CIS-2,3-DIHYDROBIPHENYL-2,3-DIOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Dhindwal, S, Patil, D.N, Kumar, P.
Deposit date:2011-07-23
Release date:2011-08-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Biochemical Studies and Ligand-Bound Structures of Biphenyl Dehydrogenase from Pandoraea Pnomenusa Strain B-356 Reveal a Basis for Broad Specificity of the Enzyme.
J.Biol.Chem., 286, 2011
3QTE
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BU of 3qte by Molmil
Crystal structure of human alpha-defensin 6 (H27W mutant)
Descriptor: CHLORIDE ION, Defensin-6, GLYCEROL
Authors:Pazgier, M, Lu, W.
Deposit date:2011-02-22
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Human alpha-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets.
Science, 337, 2012
2DP3
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Crystal structure of a double mutant (C202A/A198V) of Triosephosphate isomerase from giardia lamblia
Descriptor: SULFATE ION, Triosephosphate isomerase
Authors:Diaz, A, Reyes-Vivas, H, Lopez-Velazquez, G.
Deposit date:2006-05-05
Release date:2007-01-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Disulfide Bridges in the Mesophilic Triosephosphate Isomerase from Giardia lamblia Are Related to Oligomerization and Activity
J.Mol.Biol., 365, 2007
4OIL
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BU of 4oil by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, co-regulator peptide
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-19
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OKW
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BU of 4okw by Molmil
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, R-BICALUTAMIDE, co-regulator peptide
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-23
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
2KV3
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BU of 2kv3 by Molmil
Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant
Descriptor: Regenerating islet-derived protein 4
Authors:Ho, M, Lou, Y, Chen, C.
Deposit date:2010-03-04
Release date:2010-08-18
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Human RegIV protein adopts a typical C-type lectin fold but binds mannan with two calcium-independent sites.
J.Mol.Biol., 402, 2010
4BZR
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BU of 4bzr by Molmil
Human testis angiotensin converting enzyme in complex with K-26
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ...
Authors:Kramer, G.J, Mohd, A, Schwager, S.L.U, Masuyer, G, Acharya, K.R, Sturrock, E.D, Bachmann, B.O.
Deposit date:2013-07-29
Release date:2014-02-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes
Acs Med.Chem.Lett., 5, 2014
4OK1
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BU of 4ok1 by Molmil
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, R-BICALUTAMIDE, co-regulator peptide
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-21
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OIU
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BU of 4oiu by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, co-regulator peptide
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-20
Release date:2014-08-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OKT
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BU of 4okt by Molmil
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, R-BICALUTAMIDE, co-regulator peptide
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-22
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OLM
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BU of 4olm by Molmil
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, R-BICALUTAMIDE, co-regulator peptide
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-24
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OH5
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BU of 4oh5 by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-17
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OHA
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BU of 4oha by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-17
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OJ9
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BU of 4oj9 by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, GLYCEROL, HYDROXYFLUTAMIDE, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-20
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OGH
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BU of 4ogh by Molmil
Crystal structure of T877A-AR-LBD
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-16
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OH6
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BU of 4oh6 by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, Protein BUD31 homolog, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-17
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OKB
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BU of 4okb by Molmil
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, Protein BUD31 homolog, R-BICALUTAMIDE, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-22
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OJB
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BU of 4ojb by Molmil
Crystal structure of W741L-AR-LBD
Descriptor: Androgen receptor, R-BICALUTAMIDE
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-21
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014

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