6KZ1
 
 | | Complex structure of Whirlin and Myosin XVa | | Descriptor: | Myosin XVa, Whirlin | | Authors: | Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. | | Deposit date: | 2019-09-22 | | Release date: | 2020-09-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.694 Å) | | Cite: | Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex.
Cell Rep, 34, 2021
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6LCA
 | | Crystal structure of human Dishevelled1 PDZ domain homotrimer | | Descriptor: | SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 | | Authors: | Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. | | Deposit date: | 2019-11-18 | | Release date: | 2020-11-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of human Dishevelled1 PDZ domain homotrimer
To Be Published
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6MTV
 | | Crystal structure of human Scribble PDZ1:MCC complex | | Descriptor: | Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ... | | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | | Deposit date: | 2018-10-22 | | Release date: | 2019-08-14 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.597 Å) | | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019
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3VQF
 | | Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein | | Descriptor: | E3 ubiquitin-protein ligase LNX | | Authors: | Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. | | Deposit date: | 2012-03-22 | | Release date: | 2013-03-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.199 Å) | | Cite: | Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
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3K82
 | | Crystal Structure of the third PDZ domain of PSD-95 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disks large homolog 4, GLYCEROL, ... | | Authors: | Camara-Artigas, A, Gavira, J.A. | | Deposit date: | 2009-10-13 | | Release date: | 2010-04-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
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3SFJ
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3SHU
 | | Crystal structure of ZO-1 PDZ3 | | Descriptor: | Tight junction protein ZO-1 | | Authors: | Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. | | Deposit date: | 2011-06-17 | | Release date: | 2011-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
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3JXT
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6MTU
 | | Crystal structure of human Scribble PDZ1:pMCC complex | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... | | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | | Deposit date: | 2018-10-22 | | Release date: | 2019-08-14 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.141 Å) | | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019
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6MS1
 | | Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC | | Descriptor: | 1,2-ETHANEDIOL, APC C-terminus peptide, Protein scribble homolog | | Authors: | How, J.Y, Kvansakul, M, Caria, S, Humbert, P.O. | | Deposit date: | 2018-10-16 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.
FEBS Lett., 593, 2019
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6MYE
 | | Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) | | Descriptor: | FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ... | | Authors: | Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J. | | Deposit date: | 2018-11-01 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
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6MYF
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3TSV
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6JUE
 | | The complex of PDZ and PBM | | Descriptor: | Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU | | Authors: | Liu, Z. | | Deposit date: | 2019-04-13 | | Release date: | 2020-04-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.549 Å) | | Cite: | Par complex cluster formation mediated by phase separation.
Nat Commun, 11, 2020
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3VQG
 | | Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein | | Descriptor: | C-terminal peptide from Immunoglobulin superfamily member 5, E3 ubiquitin-protein ligase LNX, SULFATE ION | | Authors: | Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. | | Deposit date: | 2012-03-23 | | Release date: | 2013-03-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
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6NID
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2AWW
 | | Synapse associated protein 97 PDZ2 domain variant C378G with C-terminal GluR-A peptide | | Descriptor: | 18-residue C-terminal peptide from glutamate receptor, ionotropic, AMPA1, ... | | Authors: | Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-08-29 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
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2AIN
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2AWX
 | | Synapse associated protein 97 PDZ2 domain variant C378S | | Descriptor: | HISTIDINE, Synapse associated protein 97 | | Authors: | Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-08-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
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1ZUB
 | | Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide | | Descriptor: | ELKS1b, Regulating synaptic membrane exocytosis protein 1 | | Authors: | Lu, J, Li, H, Wang, Y, Sudhof, T.C, Rizo, J. | | Deposit date: | 2005-05-30 | | Release date: | 2005-08-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide
J.Mol.Biol., 352, 2005
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1Z86
 | | Solution structure of the PDZ domain of alpha-syntrophin | | Descriptor: | Alpha-1-syntrophin | | Authors: | Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | | Deposit date: | 2005-03-30 | | Release date: | 2006-01-24 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
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2BYG
 | | 2nd PDZ Domain of Discs Large Homologue 2 | | Descriptor: | CHANNEL ASSOCIATED PROTEIN OF SYNAPSE-110 | | Authors: | Elkins, J.M, Schoch, G.A, Smee, C.E.A, Berridge, G, Salah, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-08-01 | | Release date: | 2005-08-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007
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2AWU
 | | Synapse associated protein 97 PDZ2 domain variant C378G | | Descriptor: | AHH, Synapse-associated protein 97 | | Authors: | Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-08-29 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
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2CSS
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1ZOK
 | | PDZ1 Domain Of Synapse Associated Protein 97 | | Descriptor: | Presynaptic protein SAP97 | | Authors: | Wang, L, Piserchio, A, Mierke, D.F. | | Deposit date: | 2005-05-13 | | Release date: | 2005-06-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors.
J.Biol.Chem., 280, 2005
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