PDB: 265 resultsInfo pagesStatus searchChemie searchBIRD

---

7B2T	Crystal structure of Iripin-5 serpin from Ixodes ricinus Descriptor: CHLORIDE ION, MAGNESIUM ION, Serpin-4 precursor, ... Authors: Kascakova, B, Kuta Smatanova, I. Deposit date: 2020-11-27 Release date: 2021-10-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus. Acta Crystallogr D Struct Biol, 77, 2021
4C41	Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236 Descriptor: CORTICOSTEROID-BINDING GLOBULIN Authors: Chan, W.L, Zhou, A, Read, R.J. Deposit date: 2013-08-28 Release date: 2014-10-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents. Plos One, 9, 2014
4EB1	Hyperstable in-frame insertion variant of antithrombin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III Authors: Martinez-Martinez, I, Johnson, D.J.D, Yamasaki, M, Corral, J, Huntington, J.A. Deposit date: 2012-03-23 Release date: 2012-07-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance. J.Thromb.Haemost., 10, 2012
5OM6	Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo2: a MMP9-cleavable drug-binding serpin for doxycycline Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION, ... Authors: Schmidt, K, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.849 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM7	Crystal structure of Alpha1-antichymotrypsin variant DBS-II: a drug-binding serpin for doxorubicin Descriptor: Alpha-1-antichymotrypsin, DOXORUBICIN Authors: Schmidt, K, Kern, A, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.727 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM3	Crystal structure of Alpha1-antichymotrypsin variant DBS-I5: a MMP14-cleavable drug-binding serpin for doxycycline Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, Alpha-1-antichymotrypsin, DI(HYDROXYETHYL)ETHER Authors: Schmidt, K, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM8	Crystal form 2 of Alpha1-antichymotrypsin variant DBS-II-allo: an allosterically modulated drug-binding serpin for doxorubicin Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION, ... Authors: Schmidt, K, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5NBU	Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations Descriptor: Alpha-1-antitrypsin, GLYCEROL, OXAMIC ACID Authors: Huntington, J.A, Pomowski, A, Johnson, D.J.D. Deposit date: 2017-03-02 Release date: 2018-03-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.67 Å) Cite: CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION To Be Published
5NCT	Structure of the trypsin induced serpin-type proteinase inhibitor, miropin. Descriptor: ASPARTIC ACID, GLYCEROL, SERINE, ... Authors: Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. Deposit date: 2017-03-06 Release date: 2017-05-24 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5NCU	Structure of the subtilisin induced serpin-type proteinase inhibitor, miropin. Descriptor: CHLORIDE ION, GLYCEROL, IODIDE ION, ... Authors: Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. Deposit date: 2017-03-06 Release date: 2017-05-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5OM5	Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo1: an allosterically triggered drug-binding serpin for doxycycline Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION Authors: Schmidt, K, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.595 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM2	Crystal structure of Alpha1-antichymotrypsin variant DBS-I1: a drug-binding serpin for doxycycline Descriptor: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin Authors: Schmidt, K, Muller, Y.A. Deposit date: 2017-07-28 Release date: 2018-05-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1C8O	2.9 A STRUCTURE OF CLEAVED VIRAL SERPIN CRMA Descriptor: ICE INHIBITOR Authors: Simonovic, M, Gettins, P.G.W, Volz, K. Deposit date: 2000-06-01 Release date: 2000-09-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition. Protein Sci., 9, 2000
3LW2	Mouse Plasminogen Activator Inhibitor-1 (PAI-1) Descriptor: Plasminogen activator inhibitor 1 Authors: Dewilde, M, Van De Craen, B, Compernolle, G, Madsen, J.B, Strelkov, S.V, Gils, A, Declerck, P.J. Deposit date: 2010-02-23 Release date: 2010-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences. J.Struct.Biol., 171, 2010
1D5S	CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER Descriptor: P1-ARG ANTITRYPSIN Authors: Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P. Deposit date: 1999-10-11 Release date: 2000-04-02 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3 Å) Cite: Cleaved antitrypsin polymers at atomic resolution. Protein Sci., 9, 2000
1DB2	CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 Descriptor: PLASMINOGEN ACTIVATOR INHIBITOR-1 Authors: Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P. Deposit date: 1999-11-02 Release date: 1999-11-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation. J.Mol.Biol., 297, 2000
1XU8	The 2.8 A structure of a tumour suppressing serpin Descriptor: Maspin, SULFATE ION Authors: Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. Deposit date: 2004-10-25 Release date: 2005-03-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
1DVN	LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) Descriptor: PLASMINOGEN ACTIVATOR INHIBITOR-1 Authors: Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J. Deposit date: 2000-01-21 Release date: 2000-09-13 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of active and latent PAI-1: a possible stabilizing role for chloride ions. Biochemistry, 39, 2000
1E03	PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... Authors: McCoy, A.J, Jin, L, Abrahams, J.-P, Skinner, R, Carrell, R.W. Deposit date: 2000-03-09 Release date: 2000-06-02 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
2ACH	CRYSTAL STRUCTURE OF CLEAVED HUMAN ALPHA1-ANTICHYMOTRYPSIN AT 2.7 ANGSTROMS RESOLUTION AND ITS COMPARISON WITH OTHER SERPINS Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTICHYMOTRYPSIN, PHOSPHATE ION, ... Authors: Baumann, U, Huber, R, Bode, W, Grosse, D, Lesjak, M, Laurell, C.B. Deposit date: 1993-04-26 Release date: 1993-07-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins. J.Mol.Biol., 218, 1991
1DZG	N135Q-S380C-ANTITHROMBIN-III Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... Authors: McCoy, A.J, Huntington, J.A, Carrell, R.W. Deposit date: 2000-02-28 Release date: 2000-05-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions. J.Biol.Chem., 275, 2000
3OZQ	Crystal structure of Serpin48, which is a highly specific serpin in the insect Tenebrio molitor Descriptor: Serpin48 Authors: Park, S.H, Piao, S, Ha, N.-C. Deposit date: 2010-09-27 Release date: 2010-10-27 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and functional characterization of a highly specific serpin in the insect innate immunity J.Biol.Chem., 286, 2011
1DZH	P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... Authors: Mccoy, A.J, Huntington, J.A, Carrell, R.W. Deposit date: 2000-02-28 Release date: 2000-05-26 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.85 Å) Cite: The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions. J.Biol.Chem., 275, 2000
1E05	PLASMA ALPHA ANTITHROMBIN-III Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... Authors: McCoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W. Deposit date: 2000-03-09 Release date: 2000-06-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
1E04	PLASMA BETA ANTITHROMBIN-III Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, GLYCEROL, ... Authors: Mccoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W. Deposit date: 2000-03-09 Release date: 2000-06-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003

<1234567891011>