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1ME8
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP bound
Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ...
Authors:Prosise, G.L, Wu, J, Luecke, H.
Deposit date:2002-08-08
Release date:2003-01-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
J.Biol.Chem., 277, 2002
1ME9
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP bound
Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, POTASSIUM ION
Authors:Prosise, G.L, Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEA
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METHIONYL-TRNA SYNTHETASE ZINC BINDING DOMAIN. 3D STRUCTURE AND HOMOLOGY WITH RUBREDOXIN AND GAG RETROVIRAL PROTEINS
Descriptor: METHIONYL-tRNA SYNTHETASE, ZINC ION
Authors:Fourmy, D, Dardel, F.
Deposit date:1992-11-09
Release date:1993-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Methionyl-tRNA synthetase zinc binding domain. Three-dimensional structure and homology with rubredoxin and gag retroviral proteins.
J.Mol.Biol., 231, 1993
1MEC
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CONFORMATIONAL VARIABILITY OF A PICORNAVIRUS CAPSID: PH-DEPENDENT STRUCTURAL CHANGES OF MENGO VIRUS RELATED TO ITS HOST RECEPTOR ATTACHMENT SITE AND DISASSEMBLY
Descriptor: MENGO VIRUS COAT PROTEIN (SUBUNIT VP1), MENGO VIRUS COAT PROTEIN (SUBUNIT VP2), PHOSPHATE ION
Authors:Rossmann, M.G.
Deposit date:1992-01-17
Release date:1994-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational variability of a picornavirus capsid: pH-dependent structural changes of Mengo virus related to its host receptor attachment site and disassembly.
Virology, 175, 1990
1MED
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METHIONYL-TRNA SYNTHETASE ZINC BINDING DOMAIN. 3D STRUCTURE AND HOMOLOGY WITH RUBREDOXIN AND GAG RETROVIRAL PROTEINS
Descriptor: METHIONYL-tRNA SYNTHETASE, ZINC ION
Authors:Fourmy, D, Dardel, F.
Deposit date:1992-11-09
Release date:1993-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Methionyl-tRNA synthetase zinc binding domain. Three-dimensional structure and homology with rubredoxin and gag retroviral proteins.
J.Mol.Biol., 231, 1993
1MEE
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THE COMPLEX BETWEEN THE SUBTILISIN FROM A MESOPHILIC BACTERIUM AND THE LEECH INHIBITOR EGLIN-C
Descriptor: CALCIUM ION, EGLIN C, MESENTERICOPEPTIDASE
Authors:Dauter, Z, Betzel, C, Wilson, K.S.
Deposit date:1991-04-15
Release date:1992-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Complex between the subtilisin from a mesophilic bacterium and the leech inhibitor eglin-C.
Acta Crystallogr.,Sect.B, 47, 1991
1MEG
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CRYSTAL STRUCTURE OF A CARICAIN D158E MUTANT IN COMPLEX WITH E-64
Descriptor: CARICAIN, ETHANOL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
Authors:Katerelos, N.A.
Deposit date:1996-05-04
Release date:1997-01-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a caricain D158E mutant in complex with E-64.
FEBS Lett., 392, 1996
1MEH
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP and MOA bound
Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ...
Authors:Prosise, G.L, Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEI
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and mycophenolic acid bound
Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ...
Authors:Prosise, G.L, Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEJ
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Human Glycinamide Ribonucleotide Transformylase domain at pH 8.5
Descriptor: GLYCEROL, PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase
Authors:Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A.
Deposit date:2002-08-08
Release date:2002-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
1MEK
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HUMAN PROTEIN DISULFIDE ISOMERASE, NMR, 40 STRUCTURES
Descriptor: PROTEIN DISULFIDE ISOMERASE
Authors:Kemmink, J, Darby, N.J, Dijkstra, K, Nilges, M, Creighton, T.E.
Deposit date:1996-04-16
Release date:1997-04-21
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structure determination of the N-terminal thioredoxin-like domain of protein disulfide isomerase using multidimensional heteronuclear 13C/15N NMR spectroscopy.
Biochemistry, 35, 1996
1MEL
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CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME
Descriptor: LYSOZYME, VH SINGLE-DOMAIN ANTIBODY
Authors:Desmyter, A, Transue, T.R, Arbabi Gharoudi, M, Dao Thi, M, Poortmans, F, Hamers, R, Muyldermans, S, Wyns, L.
Deposit date:1996-06-06
Release date:1997-06-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme.
Nat.Struct.Biol., 3, 1996
1MEM
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Crystal structure of Cathepsin K complexed with a potent vinyl sulfone inhibitor
Descriptor: Cathepsin K, N-{(1R)-3-phenyl-1-[2-(phenylsulfonyl)ethyl]propyl}-N~2~-(piperazin-1-ylcarbonyl)-L-leucinamide
Authors:Mcgrath, M.E.
Deposit date:1997-01-08
Release date:1998-01-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human cathepsin K complexed with a potent inhibitor.
Nat.Struct.Biol., 4, 1997
1MEN
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complex structure of human GAR Tfase and substrate beta-GAR
Descriptor: GLYCINAMIDE RIBONUCLEOTIDE, Phosphoribosylglycinamide formyltransferase
Authors:Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A.
Deposit date:2002-08-08
Release date:2002-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
1MEO
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human glycinamide ribonucleotide Transformylase at pH 4.2
Descriptor: PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase, SULFATE ION
Authors:Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A.
Deposit date:2002-08-08
Release date:2002-12-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
1MEP
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Crystal Structure of Streptavidin Double Mutant S45A/D128A with Biotin: Cooperative Hydrogen-Bond Interactions in the Streptavidin-Biotin System.
Descriptor: BIOTIN, Streptavidin
Authors:Hyre, D.E, Le Trong, I, Merritt, E.A, Stenkamp, R.E, Green, N.M, Stayton, P.S.
Deposit date:2002-08-08
Release date:2003-09-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Cooperative hydrogen bond interactions in the streptavidin-biotin system
Protein Sci., 15, 2006
1MEQ
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HIV gp120 C5
Descriptor: Exterior Membrane Glycoprotein (GP120)
Authors:Caffrey, M, Jacobs, A, Guilhaudis, L.
Deposit date:2002-08-08
Release date:2002-12-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the HIV gp120 C5 Domain
Eur.J.Biochem., 269, 2002
1MER
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HIV-1 MUTANT (I84V) PROTEASE COMPLEXED WITH DMP450
Descriptor: HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-1,3-BIS([(3-AMINO)PHENYL]METHYL)-4,7-BIS(PHENYLMETHYL)-2H-1,3-DIAZEPINONE
Authors:Ala, P, Chang, C.-H.
Deposit date:1997-04-11
Release date:1998-04-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
Biochemistry, 36, 1997
1MES
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HIV-1 MUTANT (I84V) PROTEASE COMPLEXED WITH DMP323
Descriptor: HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE
Authors:Ala, P, Chang, C.-H.
Deposit date:1997-04-11
Release date:1998-04-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
Biochemistry, 36, 1997
1MET
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HIV-1 MUTANT (V82F) PROTEASE COMPLEXED WITH DMP323
Descriptor: HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE
Authors:Ala, P, Chang, C.-H.
Deposit date:1997-04-11
Release date:1998-04-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
Biochemistry, 36, 1997
1MEU
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HIV-1 MUTANT (V82F, I84V) PROTEASE COMPLEXED WITH DMP323
Descriptor: HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE
Authors:Ala, P, Chang, C.-H.
Deposit date:1997-04-11
Release date:1998-04-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
Biochemistry, 36, 1997
1MEW
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound
Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ...
Authors:Prosise, G.L, Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEX
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Antibody Catalysis of a Bimolecular Cycloaddition Reaction
Descriptor: 4-(2-DIMETHYLCARBAMOYL-PHENYLCARBAMOYLOXYMETHYL)-BENZOIC ACID, Fab 29G12 heavy chain, Fab 29G12 light chain
Authors:Heine, A, Wilson, I.A.
Deposit date:2002-08-08
Release date:2003-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Antibody Catalysis of a Bimolecular Cycloaddition Reaction
To be Published
1MEY
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CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA
Descriptor: CHLORIDE ION, CONSENSUS ZINC FINGER, DNA (5'-D(*AP*TP*GP*AP*GP*GP*CP*AP*GP*AP*AP*CP*T)-3'), ...
Authors:Kim, C.A, Berg, J.M.
Deposit date:1996-09-27
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A 2.2 A Resolution Crystal Structure of a Designed Zinc Finger Protein Bound to DNA
Nat.Struct.Biol., 3, 1996
1MEZ
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Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with SAMP, GDP, SO4(2-), and Mg(2+)
Descriptor: 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B.
Deposit date:2002-08-09
Release date:2002-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase.
J.Biol.Chem., 277, 2002

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