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3VXU
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The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
2VIR
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BU of 2vir by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
Descriptor: HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ...
Authors:Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
Deposit date:1997-12-22
Release date:1998-04-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
3VXM
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The complex between C1-28 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, C1-28 TCR alpha chain, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
5IUE
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Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP, ...
Authors:Dulberger, C.L, Adams, E.J.
Deposit date:2016-03-17
Release date:2017-06-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.
Immunity, 46, 2017
5IVX
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Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Natarajan, K, Jiang, J, Margulies, D.
Deposit date:2016-03-21
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
3WS6
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Crystal Structure of H-2D in complex with a mimotopic peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Kumar, P.R, Mukherjee, G, Samanta, D, DiLorenzo, T.P, Almo, S.C, Immune Function Network, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-02-28
Release date:2014-03-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses
J. Immunol., 193, 2014
2X4U
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Crystal structure of MHC CLass I HLA-A2.1 bound to HIV-1 Peptide RT468-476
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
Authors:Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
Deposit date:2010-02-02
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals.
J.Am.Chem.Soc., 131, 2009
3W39
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Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-52 alpha chain, ...
Authors:Yagita, Y, Kuse, N, Kuroki, K, Gatanaga, H, Carlson, J.M, Chikata, T, Brumme, Z.L, Murakoshi, H, Akahoshi, T, Pfeifer, N, Mallal, S, John, M, Ose, T, Matsubara, H, Kanda, R, Fukunaga, Y, Honda, K, Kawashima, Y, Ariumi, Y, Oka, S, Maenaka, K, Takiguchi, M.
Deposit date:2012-12-13
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity
J.Virol., 87, 2013
2WY3
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Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands
Descriptor: 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Mueller, S, Zocher, G, Steinle, A, Stehle, T.
Deposit date:2009-11-11
Release date:2010-02-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the Hcmv Ul16-Micb Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse Nkg2D Ligands.
Plos Pathog., 6, 2010
5J6G
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Recognition of the MHC class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, Q10 alpha chain, ...
Authors:Berry, R, Rossjohn, J.
Deposit date:2016-04-04
Release date:2016-07-13
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J.Biol.Chem., 291, 2016
2VLJ
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The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
Descriptor: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VLL
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BU of 2vll by Molmil
The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
Descriptor: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2X4T
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Crystal structure of MHC CLass I HLA-A2.1 bound to a Peiodate- cleavable peptide
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 65 KDA PHOSPHOPROTEIN, BETA-2-MICROGLOBULIN, ...
Authors:Rodenko, B, Toebes, M, Celie, P.H.N, Perrakis, A, Schumacher, T.N.M, Ovaa, H.
Deposit date:2010-02-02
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
2X4Q
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Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
Authors:Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
Deposit date:2010-02-02
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
2X70
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BU of 2x70 by Molmil
Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
Authors:Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
Deposit date:2010-02-22
Release date:2010-12-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals.
J.Am.Chem.Soc., 131, 2009
2X4P
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BU of 2x4p by Molmil
Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
Authors:Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
Deposit date:2010-02-02
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
J.Am.Chem.Soc., 131, 2009
5J6H
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BU of 5j6h by Molmil
Recognition of the MHC class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, Q10 alpha chain, ...
Authors:Berry, R, Rossjohn, J.
Deposit date:2016-04-05
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J.Biol.Chem., 291, 2016
3WS3
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BU of 3ws3 by Molmil
Crystal Structure of H-2D in complex with an insulin derived peptide
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Kumar, P.R, Mukherjee, G, Samanta, D, DiLorenzo, T.P, Almo, S.C, Immune Function Network, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-02-28
Release date:2014-03-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.335 Å)
Cite:Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses
J. Immunol., 193, 2014
2V2W
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BU of 2v2w by Molmil
T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT
Descriptor: BETA-2 MICROGLOBULIN, HIV P17, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Lee, J.K, Stewart-Jones, G, Dong, T, Harlos, K, Di Gleria, K, Dorrell, L, Douek, D.C, Van Der Merwe, P.A, Jones, E.Y, Mcmichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2V2X
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BU of 2v2x by Molmil
T cell cross-reactivity and conformational changes during TCR engagement.
Descriptor: BETA-2 MICROGLOBULIN, HIV P17, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Lee, J.K, Stewart-Jones, G, Dong, T, harlos, K, Di Gleria, K, Dorrell, L, Douek, D.C, van der Merwe, P.A, Jones, E.Y, McMichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2UWE
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BU of 2uwe by Molmil
Large CDR3a loop alteration as a function of MHC mutation
Descriptor: AHIII TCR ALPHA CHAIN, AHIII TCR BETA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Miller, P.J, Pazy, Y, Conti, B, Riddle, D, Biddison, W.E, Appella, E, Collins, E.J.
Deposit date:2007-03-20
Release date:2007-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
J.Mol.Biol., 373, 2007
3WEX
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Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen
Authors:Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-16
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014
2WBJ
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TCR complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
Authors:Harkiolaki, M, Holmes, S.L, Svendsen, P, Gregersen, J.W, Jensen, L.T, McMahon, R, Friese, M.A, van Boxel, G, Etzensperger, R, Tzartos, J.S, Kranc, K, Sainsbury, S, Harlos, K, Mellins, E.D, Palace, J, Esiri, M.M, van der Merwe, P.A, Jones, E.Y, Fugger, L.
Deposit date:2009-03-02
Release date:2009-04-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Immunity, 30, 2009
5JWE
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BU of 5jwe by Molmil
Crystal structure of H-2Db in complex with the LCMV-derived GP92-101 peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Buratto, J, Badia-Martinez, D, Norstrom, M, Sandalova, T, Achour, A.
Deposit date:2016-05-12
Release date:2017-05-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
PLoS ONE, 12, 2017
3WLB
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BU of 3wlb by Molmil
HLA-A24 in complex with HIV-1 Nef126-10(8T10F)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A, Han, C.
Deposit date:2013-11-08
Release date:2014-06-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Switching and emergence of CTL epitopes in HIV-1 infection
Retrovirology, 11, 2014

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