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3C2K
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BU of 3c2k by Molmil
DNA POLYMERASE BETA with a gapped DNA substrate and DUMPNPP with Manganese in the active site
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), ...
Authors:Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H.
Deposit date:2008-01-25
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation.
Mol.Cell, 30, 2008
1SVC
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BU of 1svc by Molmil
NFKB P50 HOMODIMER BOUND TO DNA
Descriptor: DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB))
Authors:Mueller, C.W, Harrison, S.C.
Deposit date:1995-11-27
Release date:1996-06-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the NF-kappa B p50 homodimer bound to DNA.
Nature, 373, 1995
8V5D
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BU of 8v5d by Molmil
Human mitochondrial DNA polymerase catalytic subunit, PolG, in an APO conformation
Descriptor: DNA polymerase subunit gamma-1
Authors:Riccio, A.A, Brannon, A.J, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C.
Deposit date:2023-11-30
Release date:2024-07-10
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis.
Nucleic Acids Res., 52, 2024
4GCT
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BU of 4gct by Molmil
structure of No factor protein-DNA complex
Descriptor: DNA (5'-D(*TP*TP*AP*CP*GP*TP*GP*AP*GP*TP*AP*CP*TP*CP*AP*CP*GP*TP*AP*A)-3'), Nucleoid occlusion factor SlmA
Authors:Schumacher, M.A.
Deposit date:2012-07-30
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GCK
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BU of 4gck by Molmil
structure of no-dna complex
Descriptor: DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*TP*CP*AP*C)-3'), Nucleoid occlusion factor SlmA
Authors:Schumacher, M.A.
Deposit date:2012-07-30
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
7SDP
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BU of 7sdp by Molmil
Replication Initiator Protein REPE54 and cognate DNA sequence with terminal three prime phosphates.
Descriptor: DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*A)-3'), MAGNESIUM ION, ...
Authors:Ward, A.R, Snow, C.D.
Deposit date:2021-09-29
Release date:2021-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds.
Acs Nano, 17, 2023
4GAT
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BU of 4gat by Molmil
SOLUTION NMR STRUCTURE OF THE WILD TYPE DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13BP DNA CONTAINING A CGATA SITE, REGULARIZED MEAN STRUCTURE
Descriptor: DNA (5'-D(*CP*AP*GP*CP*GP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*CP*GP*CP*TP*G)-3'), NITROGEN REGULATORY PROTEIN AREA, ...
Authors:Clore, G.M, Starich, M, Wikstrom, M, Gronenborn, A.M.
Deposit date:1997-11-07
Release date:1998-01-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of a fungal AREA protein-DNA complex: an alternative binding mode for the basic carboxyl tail of GATA factors.
J.Mol.Biol., 277, 1998
1GAT
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BU of 1gat by Molmil
SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR
Descriptor: DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ...
Authors:Clore, G.M, Omichinski, J.G, Gronenborn, A.M.
Deposit date:1993-06-28
Release date:1993-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science, 261, 1993
1XBR
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BU of 1xbr by Molmil
T DOMAIN FROM XENOPUS LAEVIS BOUND TO DNA
Descriptor: DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*G P*TP*GP*AP*AP*AP* TP*T)-3'), PROTEIN (T PROTEIN)
Authors:Muller, C.W.
Deposit date:1997-07-16
Release date:1998-01-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.
Nature, 389, 1997
1BBX
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BU of 1bbx by Molmil
NON-SPECIFIC PROTEIN-DNA INTERACTIONS IN THE SSO7D-DNA COMPLEX, NMR, 1 STRUCTURE
Descriptor: DNA (5'-D(*CP*TP*AP*GP*CP*GP*CP*GP*CP*TP*AP*G)-3'), DNA-BINDING PROTEIN 7D
Authors:Agback, P, Baumann, H, Knapp, S, Ladenstein, R, Hard, T.
Deposit date:1998-04-24
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Architecture of Nonspecific Protein-DNA Interactions in the Sso7D-DNA Complex
Nat.Struct.Biol., 5, 1998
1PUE
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BU of 1pue by Molmil
PU.1 ETS DOMAIN-DNA COMPLEX
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*GP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*CP*CP*TP*TP*TP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR PU.1 (TF PU.1))
Authors:Kodandapani, R, Pio, F, Ni, C.Z, Piccialli, G, Klemsz, M, McKercher, S, Maki, R.A, Ely, K.R.
Deposit date:1996-07-08
Release date:1997-02-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex.
Nature, 380, 1996
5IXA
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BU of 5ixa by Molmil
HCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt
Descriptor: DNA polymerase processivity factor
Authors:Chen, H, Coen, D.M, Hogle, J.M, Filman, D.J.
Deposit date:2016-03-23
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.684 Å)
Cite:A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
ACS Infect Dis, 3, 2017
7K5P
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BU of 7k5p by Molmil
Bst DNA polymerase I time-resolved structure, 4 min post dATP addition
Descriptor: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
Authors:Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
Deposit date:2020-09-17
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
4IRI
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BU of 4iri by Molmil
Auto-inhibited ERG Ets Domain-DNA Complex
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*G)-3'), Transcriptional regulator ERG
Authors:Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H.
Deposit date:2013-01-14
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA, 110, 2013
6DSY
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BU of 6dsy by Molmil
Bst DNA polymerase I post-chemistry (n+1) structure
Descriptor: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
Authors:Chim, N, Jackson, L.N, Chaput, J.C.
Deposit date:2018-06-14
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
Authors:De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
Deposit date:2018-05-15
Release date:2018-05-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6DSV
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BU of 6dsv by Molmil
Bst DNA polymerase I post-chemistry (n+2) structure
Descriptor: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
Authors:Chim, N, Jackson, L.N, Chaput, J.C.
Deposit date:2018-06-14
Release date:2018-10-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
6DSX
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BU of 6dsx by Molmil
Bst DNA polymerase I post-chemistry (n+1 with dATP soak) structure
Descriptor: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
Authors:Chim, N, Jackson, L.N, Chaput, J.C.
Deposit date:2018-06-14
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife, 7, 2018
4I8T
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BU of 4i8t by Molmil
C.Esp1396I bound to a 19 base pair DNA duplex
Descriptor: DNA (5'-D(P*TP*GP*TP*GP*TP*GP*AP*TP*TP*AP*TP*AP*GP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(P*TP*GP*TP*TP*GP*AP*CP*TP*AP*TP*AP*AP*TP*CP*AP*CP*AP*CP*A)-3'), Regulatory protein
Authors:Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
Deposit date:2012-12-04
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of DNA-protein complexes regulating the restriction-modification system Esp1396I.
Acta Crystallogr.,Sect.F, 69, 2013
1JMC
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BU of 1jmc by Molmil
SINGLE STRANDED DNA-BINDING DOMAIN OF HUMAN REPLICATION PROTEIN A BOUND TO SINGLE STRANDED DNA, RPA70 SUBUNIT, RESIDUES 183-420
Descriptor: DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*C)-3'), PROTEIN (REPLICATION PROTEIN A (RPA))
Authors:Bochkarev, A, Pfuetzner, R, Edwards, A, Frappier, L.
Deposit date:1996-11-11
Release date:1997-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA.
Nature, 385, 1997
5JZQ
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BU of 5jzq by Molmil
Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals massive presence of multiple conformations
Descriptor: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Drozdzal, P, Gilski, M, Jaskolski, M.
Deposit date:2016-05-17
Release date:2016-11-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (0.78 Å)
Cite:Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals the massive presence of alternate conformations.
Acta Crystallogr D Struct Biol, 72, 2016
6P1S
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BU of 6p1s by Molmil
Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated AMP
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Kaminski, A.M, Pedersen, L.C, Bebenek, K, Chiruvella, K.K, Ramsden, D.A, Kunkel, T.A.
Deposit date:2019-05-20
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res., 47, 2019
7DCU
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BU of 7dcu by Molmil
Crystal structure of HSF2 DNA-binding domain in complex with 3-site HSE DNA (21 bp)
Descriptor: DNA (5'-D(*AP*CP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*G)-3'), Heat shock factor protein 2, ...
Authors:Feng, N, Liu, W.
Deposit date:2020-10-27
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of heat shock factor trimers bound to DNA.
Iscience, 24, 2021
3DFV
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BU of 3dfv by Molmil
Adjacent GATA DNA binding
Descriptor: DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L, Kim, G.K, Guo, L, Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
1GAU
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BU of 1gau by Molmil
SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR GATA-1 BY MULTIDIMENSIONAL NMR
Descriptor: DNA (5'-D(P*AP*GP*AP*TP*AP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*TP*AP*TP*CP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1
Authors:Clore, G.M, Omichinski, J.G, Gronenborn, A.M.
Deposit date:1993-06-28
Release date:1993-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science, 261, 1993

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