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5HZK
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BU of 5hzk by Molmil
Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain in complex with Cdc42
Descriptor: Cell division control protein 42 homolog, FLAVIN MONONUCLEOTIDE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Tarnawski, M, Dagliyan, O, Chu, P.H, Shirvanyants, D, Dokholyan, N.V, Hahn, K.M, Schlichting, I.
Deposit date:2016-02-02
Release date:2016-12-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Engineering extrinsic disorder to control protein activity in living cells.
Science, 354, 2016
4O87
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BU of 4o87 by Molmil
Crystal structure of a N-tagged Nuclease
Descriptor: CITRIC ACID, N-tagged Nuclease, SULFATE ION
Authors:Chakravarty, A.K, Smith, P, Shuman, S.
Deposit date:2013-12-26
Release date:2014-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination.
Cell Rep, 7, 2014
1D5D
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BU of 1d5d by Molmil
The role of phenylalanine 8 in the stabilization of the s protein-s peptide interaction: packing and cavities
Descriptor: RNASE S, S PEPTIDE, SULFATE ION
Authors:Ratnaparkhi, G.S, Varadarajan, R.
Deposit date:1999-10-07
Release date:1999-10-20
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics.
Biochemistry, 39, 2000
4O88
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BU of 4o88 by Molmil
Crystal structure of a C-tagged Nuclease
Descriptor: CHLORIDE ION, N-tagged Nuclease, SULFATE ION
Authors:Chakravarty, A.K, Smith, P, Shuman, S.
Deposit date:2013-12-26
Release date:2014-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination.
Cell Rep, 7, 2014
4JBR
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BU of 4jbr by Molmil
tRNA-guanine transglycosylase Y330C mutant as covalently linked dimer in space group P6(5)22
Descriptor: DIMETHYL SULFOXIDE, ZINC ION, tRNA-guanine transglycosylase
Authors:Jakobi, S, Klebe, G.
Deposit date:2013-02-20
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface.
Acs Chem.Biol., 16, 2021
1D5E
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BU of 1d5e by Molmil
The role of phenylalanine 8 in the stabilization of the S protein-S peptide interaction: Packing and cavities
Descriptor: RNASE S, S PEPTIDE, SULFATE ION
Authors:Ratnaparkhi, G.S, Varadarajan, R.
Deposit date:1999-10-07
Release date:1999-10-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics.
Biochemistry, 39, 2000
4IPP
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BU of 4ipp by Molmil
tRNA-guanine-transglycosylase (TGT) mutant V262D APO-Structure
Descriptor: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION
Authors:Neeb, M, Heine, A, Klebe, G.
Deposit date:2013-01-10
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Investigating the advantage of ligands with residual mobility in binding mutated TGT
To be Published
2MTJ
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BU of 2mtj by Molmil
NMR structure of the III-IV-V three-way junction from the VS ribozyme
Descriptor: RNA (47-MER)
Authors:Bonneau, E, Legault, P.
Deposit date:2014-08-19
Release date:2014-10-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Structure of the III-IV-V Three-Way Junction from the Varkud Satellite Ribozyme and Identification of Magnesium-Binding Sites Using Paramagnetic Relaxation Enhancement.
Biochemistry, 53, 2014
5M8C
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BU of 5m8c by Molmil
Spliceosome component
Descriptor: Pre-mRNA-processing factor 19
Authors:Moura, T.R, Pena, V.
Deposit date:2016-10-28
Release date:2018-02-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
3KO7
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BU of 3ko7 by Molmil
DTD from Plasmodium falciparum in complex with D-Lysine
Descriptor: D-LYSINE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
3KOD
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BU of 3kod by Molmil
DTD from Plasmodium falciparum in complex with D-Serine
Descriptor: D-SERINE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
4ZB4
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BU of 4zb4 by Molmil
Spliceosome component
Descriptor: Pre-mRNA-processing factor 19
Authors:Rocha de Moura, T, Pena, P.
Deposit date:2015-04-14
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Spliceosome component
To Be Published
1CH0
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BU of 1ch0 by Molmil
RNASE T1 VARIANT WITH ALTERED GUANINE BINDING SEGMENT
Descriptor: CALCIUM ION, CHLORIDE ION, GUANOSINE-2'-MONOPHOSPHATE, ...
Authors:Hoeschler, K, Hoier, H, Orth, P, Hubner, B, Saenger, W, Hahn, U.
Deposit date:1999-03-30
Release date:1999-12-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of an RNase T1 variant with an altered guanine binding segment.
J.Mol.Biol., 294, 1999
3C2Y
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BU of 3c2y by Molmil
tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-2-methyl-1,7-dihydro-imidazo[4,5-g]quinazolin-8-one
Descriptor: 6-amino-2-methyl-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
Authors:Ritschel, T, Heine, A, Klebe, G.
Deposit date:2008-01-26
Release date:2009-02-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT
Chembiochem, 10, 2009
3KOB
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BU of 3kob by Molmil
DTD from Plasmodium falciparum in complex with D-Glutamic acid
Descriptor: D-GLUTAMIC ACID, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
3KOC
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BU of 3koc by Molmil
DTD from Plasmodium falciparum in complex with D-Histidine
Descriptor: D-HISTIDINE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
3KO9
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BU of 3ko9 by Molmil
DTD from Plasmodium falciparum in complex with D-Arginine
Descriptor: D-ARGININE, D-tyrosyl-tRNA(Tyr) deacylase
Authors:Manickam, Y, Bhatt, T.K, Sharma, A.
Deposit date:2009-11-13
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase
J.Biol.Chem., 285, 2010
2Z7K
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BU of 2z7k by Molmil
tRNA-Guanine transglycosylase (TGT) in complex with 2-Amino-lin-Benzoguanine
Descriptor: 2,6-diamino-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
Authors:Ritschel, T, Heine, A, Klebe, G.
Deposit date:2007-08-24
Release date:2008-08-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT
Chembiochem, 10, 2009
1ATO
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BU of 1ato by Molmil
THE STRUCTURE OF THE ISOLATED, CENTRAL HAIRPIN OF THE HDV ANTIGENOMIC RIBOZYME, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*CP*AP*CP*CP*UP*CP*CP*UP*CP*GP*CP*GP*GP*UP*GP*CP*C)-3')
Authors:Kolk, M.H, Heus, H.A, Hilbers, C.W.
Deposit date:1997-08-14
Release date:1997-11-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of the isolated, central hairpin of the HDV antigenomic ribozyme: novel structural features and similarity of the loop in the ribozyme and free in solution.
EMBO J., 16, 1997
6MWY
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BU of 6mwy by Molmil
The Prp8 intein of Cryptococcus gattii
Descriptor: Pre-mRNA-processing-splicing factor 8
Authors:Li, Z, Fu, B, Green, C.M, Lang, Y, Zhang, J, Oven, T.S, Li, X, Callahan, B.P, Chaturvedi, S, Belfort, M, Liao, G, Li, H.
Deposit date:2018-10-30
Release date:2019-11-06
Last modified:2020-05-20
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein.
Emerg Microbes Infect, 8, 2019
4JAB
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BU of 4jab by Molmil
U/G Wobble Base Pair in a RNA Duplex
Descriptor: RNA (5'-R(*GP*UP*GP*UP*AP*UP*AP*C)-3'), STRONTIUM ION
Authors:Jiang, S, Sun, H, Gan, J, Huang, Z.
Deposit date:2013-02-18
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:2-Se Uridine enhanced U/G Wobble Base Pair Discrimination
To be Published
2KPC
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BU of 2kpc by Molmil
Structure determination of the top-loop of the conserved 3 terminal secondary structure in the genome of YFV
Descriptor: RNA (5'-R(*UP*GP*AP*GP*CP*AP*CP*AP*GP*UP*UP*UP*GP*CP*UP*CP*A)-3')
Authors:Lescrinier, E, Dyubankova, N, Nauwelaerts, K, Jones, R, Herdewijn, P.
Deposit date:2009-10-12
Release date:2010-06-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure Determination of the Top-Loop of the Conserved 3'-Terminal Secondary Structure in the Genome of Flaviviruses.
Chembiochem, 11, 2010
2KPD
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BU of 2kpd by Molmil
Structure determination of the top-loop of the conserved 3 terminal secondary structure in the genome of YFV-mutant
Descriptor: RNA (5'-R(*UP*GP*AP*GP*CP*UP*CP*AP*GP*UP*UP*UP*GP*CP*UP*CP*A)-3')
Authors:Lescrinier, E, Dyubankova, N, Nauwelaerts, K, Jones, R, Herdewijn, P.
Deposit date:2009-10-12
Release date:2010-06-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure Determination of the Top-Loop of the Conserved 3'-Terminal Secondary Structure in the Genome of Flaviviruses.
Chembiochem, 11, 2010
2VQ9
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BU of 2vq9 by Molmil
RNASE ZF-3E
Descriptor: CHLORIDE ION, RNASE 1
Authors:Kazakou, K, Holloway, D.E, Prior, S.H, Subramanian, V, Acharya, K.R.
Deposit date:2008-03-12
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications
J.Mol.Biol., 380, 2008
2VQ8
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BU of 2vq8 by Molmil
RNASE ZF-1A
Descriptor: CHLORIDE ION, RNASE ZF-1A
Authors:Kazakou, K, Holloway, D.E, Prior, S.H, Subramanian, V, Acharya, K.R.
Deposit date:2008-03-12
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications.
J.Mol.Biol., 380, 2008

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