1D5E

The role of phenylalanine 8 in the stabilization of the S protein-S peptide interaction: Packing and cavities

Summary for 1D5E

• Entry DOI: 10.2210/pdb1d5e/pdb
• Related: 1D5D 1D5H 1RBH
• Descriptor: S PEPTIDE, RNASE S, SULFATE ION, ... (4 entities in total)
• Functional Keywords: rnase s mutant f8(norleucine), cavity s protein, s peptide, hydrolase
• Biological source: Bos taurus (cattle); More
• Cellular location: Secreted: P61823
• Total number of polymer chains: 2
• Total formula weight: 13090.72

Authors

Ratnaparkhi, G.S.,Varadarajan, R. (deposition date: 1999-10-07, release date: 1999-10-20, Last modification date: 2023-11-15)

• Primary citation: Ratnaparkhi, G.S.,Varadarajan, R.; Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics.; Biochemistry, 39:12365-12374, 2000; PubMed: 11015216; DOI: 10.1021/bi000775k

Experimental method

X-RAY DIFFRACTION (2.25 Å)