3C2Y
tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-2-methyl-1,7-dihydro-imidazo[4,5-g]quinazolin-8-one
Summary for 3C2Y
Entry DOI | 10.2210/pdb3c2y/pdb |
Related | 2BBF 2Z7K 3C2N 3C2Z |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-methyl-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total) |
Functional Keywords | transferase, tim barrel, glycosyltransferase, metal-binding, queuosine biosynthesis, trna processing |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43666.79 |
Authors | Ritschel, T.,Heine, A.,Klebe, G. (deposition date: 2008-01-26, release date: 2009-02-03, Last modification date: 2023-11-01) |
Primary citation | Ritschel, T.,Hoertner, S.,Heine, A.,Diederich, F.,Klebe, G. Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT Chembiochem, 10:716-727, 2009 Cited by PubMed: 19199329DOI: 10.1002/cbic.200800782 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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