4H40
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4H87
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7KGA
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![BU of 7kga by Molmil](/molmil-images/mine/7kga) | Crystal structure of a mosquito-borne flavivirus dumbbell RNA | Descriptor: | IRIDIUM HEXAMMINE ION, RNA (90-MER) | Authors: | Akiyama, B.M, Graham, M.E, O'Donoghue, Z, Beckham, J.D, Kieft, J.S. | Deposit date: | 2020-10-16 | Release date: | 2021-06-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication. Nucleic Acids Res., 49, 2021
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4H0A
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7MQ8
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![BU of 7mq8 by Molmil](/molmil-images/mine/7mq8) | Cryo-EM structure of the human SSU processome, state pre-A1 | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Vanden Broeck, A, Singh, S, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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7MQ9
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![BU of 7mq9 by Molmil](/molmil-images/mine/7mq9) | Cryo-EM structure of the human SSU processome, state pre-A1* | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Vanden Broeck, A, Singh, S, Klinge, S. | Deposit date: | 2021-05-05 | Release date: | 2021-09-22 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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4HFS
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7MJP
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![BU of 7mjp by Molmil](/molmil-images/mine/7mjp) | Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sung, M.W, Shyng, S.L. | Deposit date: | 2021-04-20 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MJQ
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![BU of 7mjq by Molmil](/molmil-images/mine/7mjq) | Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-sensitive inward rectifier potassium channel 8, ... | Authors: | Sung, M.W, Shyng, S.L. | Deposit date: | 2021-04-20 | Release date: | 2021-10-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MJO
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![BU of 7mjo by Molmil](/molmil-images/mine/7mjo) | Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 1 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... | Authors: | Sung, M.W, Shyng, S.L. | Deposit date: | 2021-04-20 | Release date: | 2021-10-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
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4GZV
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4H17
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4EC6
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![BU of 4ec6 by Molmil](/molmil-images/mine/4ec6) | Ntf2-like, potential transfer protein TraM from Gram-positive conjugative plasmid pIP501 | Descriptor: | Putative uncharacterized protein | Authors: | Goessweiner-Mohr, N, Grumet, L, Pavkov-Keller, T, Wang, M, Keller, W. | Deposit date: | 2012-03-26 | Release date: | 2012-12-05 | Last modified: | 2013-02-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The 2.5 A Structure of the Enterococcus Conjugation Protein TraM resembles VirB8 Type IV Secretion Proteins. J.Biol.Chem., 288, 2013
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4EDV
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![BU of 4edv by Molmil](/molmil-images/mine/4edv) | The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese | Descriptor: | BENZAMIDINE, DNA primase, MANGANESE (II) ION, ... | Authors: | Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. | Deposit date: | 2012-03-27 | Release date: | 2012-07-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases. Structure, 20, 2012
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4EFZ
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4EH6
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![BU of 4eh6 by Molmil](/molmil-images/mine/4eh6) | Human p38 MAP kinase in complex with NP-F5 and RL87 | Descriptor: | Mitogen-activated protein kinase 14, N-phenylpyridine-3-carboxamide, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine | Authors: | Over, B, Gruetter, C, Waldmann, H, Rauh, D. | Deposit date: | 2012-04-02 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
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4E5W
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![BU of 4e5w by Molmil](/molmil-images/mine/4e5w) | JAK1 kinase (JH1 domain) in complex with compound 26 | Descriptor: | DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase JAK1, [4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)piperidin-1-yl][(2S)-1-(propan-2-yl)pyrrolidin-2-yl]methanone | Authors: | Murray, J.M. | Deposit date: | 2012-03-14 | Release date: | 2012-05-30 | Last modified: | 2012-07-11 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors. J.Med.Chem., 55, 2012
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4E6F
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4E4W
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![BU of 4e4w by Molmil](/molmil-images/mine/4e4w) | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | Authors: | Gueneau, E, Legrand, P, Charbonnier, J.B. | Deposit date: | 2012-03-13 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Nat.Struct.Mol.Biol., 20, 2013
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4E5D
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![BU of 4e5d by Molmil](/molmil-images/mine/4e5d) | 2.2A resolution structure of a firefly luciferase-benzothiazole inhibitor complex | Descriptor: | 2-(2-fluorophenyl)-6-methoxy-1,3-benzothiazole, Luciferin 4-monooxygenase | Authors: | Lovell, S, Battaile, K.P, Throne, N, Shen, M, Auld, D.S, Inglese, J. | Deposit date: | 2012-03-14 | Release date: | 2012-09-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Firefly luciferase in chemical biology: a compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter. Chem.Biol., 19, 2012
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4E5L
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![BU of 4e5l by Molmil](/molmil-images/mine/4e5l) | Crystal structure of avian influenza virus PAn bound to compound 6 | Descriptor: | 2,3-DIHYDROXY-BENZOIC ACID, MANGANESE (II) ION, Polymerase protein PA, ... | Authors: | DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W. | Deposit date: | 2012-03-14 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.469 Å) | Cite: | Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease. Plos Pathog., 8, 2012
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4E76
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4E6D
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![BU of 4e6d by Molmil](/molmil-images/mine/4e6d) | JAK2 kinase (JH1 domain) triple mutant in complex with compound 7 | Descriptor: | 3-[(3R)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)piperidin-1-yl]-3-oxopropanenitrile, GLYCEROL, Tyrosine-protein kinase JAK2 | Authors: | Murray, J.M. | Deposit date: | 2012-03-15 | Release date: | 2012-05-30 | Last modified: | 2023-03-01 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors. J.Med.Chem., 55, 2012
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4E72
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4E78
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