1PJE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pje by Molmil](/molmil-images/mine/1pje) | Structure of the channel-forming trans-membrane domain of Virus protein "u"(Vpu) from HIV-1 | Descriptor: | VPU protein | Authors: | Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J. | Deposit date: | 2003-06-02 | Release date: | 2003-10-14 | Last modified: | 2024-05-22 | Method: | SOLID-STATE NMR | Cite: | Three-dimensional structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1 J.Mol.Biol., 333, 2003
|
|
2I3V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i3v by Molmil](/molmil-images/mine/2i3v) | Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant | Descriptor: | GLUTAMIC ACID, Glutamate receptor 2, ZINC ION | Authors: | Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E. | Deposit date: | 2006-08-21 | Release date: | 2006-10-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor. Cell(Cambridge,Mass.), 127, 2006
|
|
3W5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3w5e by Molmil](/molmil-images/mine/3w5e) | Crystal structure of phosphodiesterase 4B in complex with compound 31e | Descriptor: | CALCIUM ION, N-tert-butyl-2-{4-[(5,5-dioxido-2-phenyl-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl)amino]phenyl}acetamide, ZINC ION, ... | Authors: | Takahashi, M, Hanzawa, H. | Deposit date: | 2013-01-28 | Release date: | 2013-05-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors Bioorg.Med.Chem.Lett., 23, 2013
|
|
1F9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f9h by Molmil](/molmil-images/mine/1f9h) | CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF E. COLI HPPK(R92A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.50 ANGSTROM RESOLUTION | Descriptor: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION, ... | Authors: | Blaszczyk, J, Ji, X. | Deposit date: | 2000-07-10 | Release date: | 2003-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli
6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic
Studies Biochemistry, 42, 2003
|
|
2E1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e1z by Molmil](/molmil-images/mine/2e1z) | Crystal structure of Salmonella typhimurium propionate kinase (TdcD) in complex with diadenosine tetraphosphate (Ap4A) obtained after co-crystallization with ATP | Descriptor: | 1,2-ETHANEDIOL, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Propionate Kinase | Authors: | Simanshu, D.K, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2006-11-04 | Release date: | 2007-09-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity. Proteins, 70, 2008
|
|
7M0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m0q by Molmil](/molmil-images/mine/7m0q) | |
6JIC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jic by Molmil](/molmil-images/mine/6jic) | Identification and Characterization of a carboxypeptidase inhibitor from Lycium barbarum | Descriptor: | WCI | Authors: | Tan, W.L, Wong, K.H, Huang, J.Y, Tay, S.V, Wang, S.J. | Deposit date: | 2019-02-20 | Release date: | 2020-02-26 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Identification and characterization of a wolfberry carboxypeptidase inhibitor from Lycium barbarum. Food Chem, 351, 2021
|
|
3D3P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d3p by Molmil](/molmil-images/mine/3d3p) | |
2E20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e20 by Molmil](/molmil-images/mine/2e20) | Crystal structure of Salmonella typhimurium propionate kinase (TdcD) in complex with diadenosine tetraphosphate (Ap4A) | Descriptor: | 1,2-ETHANEDIOL, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Propionate Kinase | Authors: | Simanshu, D.K, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2006-11-04 | Release date: | 2007-09-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity. Proteins, 70, 2008
|
|
2E1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e1y by Molmil](/molmil-images/mine/2e1y) | |
6MK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mk5 by Molmil](/molmil-images/mine/6mk5) | |
6MZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mzt by Molmil](/molmil-images/mine/6mzt) | Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi | Descriptor: | Potassium channel toxin alpha-KTx 6.21 | Authors: | Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F. | Deposit date: | 2018-11-05 | Release date: | 2020-03-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom. Biochem. Pharmacol., 174, 2020
|
|
8G5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g5h by Molmil](/molmil-images/mine/8g5h) | Native GABA-A receptor from the mouse brain, ortho-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA, Zolpidem, and endogenous neurosteroid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2023-02-13 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
4MUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4muw by Molmil](/molmil-images/mine/4muw) | Crystal Structure of PDE10A with Novel Keto-Benzimidazole Inhibitor | Descriptor: | 2-{4-[(6,7-difluoro-1H-benzimidazol-2-yl)amino]phenoxy}-N-methyl-3,4'-bipyridin-2'-amine, GLYCEROL, SULFATE ION, ... | Authors: | Chmait, S, Jordan, S. | Deposit date: | 2013-09-23 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.639 Å) | Cite: | Design, Optimization, and Biological Evaluation of Novel Keto-Benzimidazoles as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). J.Med.Chem., 56, 2013
|
|
1Q3E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q3e by Molmil](/molmil-images/mine/1q3e) | HCN2J 443-645 in the presence of cGMP | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | Authors: | Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E. | Deposit date: | 2003-07-29 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for modulation and agonist specificity of HCN pacemaker channels Nature, 425, 2003
|
|
8G2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g2u by Molmil](/molmil-images/mine/8g2u) | Time-resolved cryo-EM study of the 70S recycling by the HflX:control-apo-70S at 900ms | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Brown, P.Z, Frank, J. | Deposit date: | 2023-02-06 | Release date: | 2023-12-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
|
|
8G34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g34 by Molmil](/molmil-images/mine/8g34) | Time-resolved cryo-EM study of the 70S recycling by the HflX:1st intermediate | Descriptor: | 16S, 23S, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Brown, P.Z, Frank, J. | Deposit date: | 2023-02-06 | Release date: | 2023-12-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
|
|
8G31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g31 by Molmil](/molmil-images/mine/8g31) | Time-resolved cryo-EM study of the 70S recycling by the HflX:2nd Intermediate | Descriptor: | 16S, 23S, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Brown, P.Z, Frank, J. | Deposit date: | 2023-02-06 | Release date: | 2023-12-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
|
|
6O3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3s by Molmil](/molmil-images/mine/6o3s) | NMR solution structure of Luffin P1 | Descriptor: | Ribosome-inactivating protein luffin P1 | Authors: | Rosengren, K.J, Payne, C. | Deposit date: | 2019-02-27 | Release date: | 2019-04-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | An Ancient Peptide Family Buried within Vicilin Precursors. Acs Chem.Biol., 14, 2019
|
|
6O3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3q by Molmil](/molmil-images/mine/6o3q) | |
2JM4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jm4 by Molmil](/molmil-images/mine/2jm4) | |
6GNZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gnz by Molmil](/molmil-images/mine/6gnz) | |
4A3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a3f by Molmil](/molmil-images/mine/4a3f) | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ... | Authors: | Cheung, A.C.M, Sainsbury, S, Cramer, P. | Deposit date: | 2011-09-30 | Release date: | 2011-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
|
|
5WXN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wxn by Molmil](/molmil-images/mine/5wxn) | Structure of the LKB1 and 14-3-3 complex | Descriptor: | 14-3-3 protein zeta/delta, Serine/threonine-protein kinase STK11 | Authors: | Ding, S, Shi, Z.B. | Deposit date: | 2017-01-08 | Release date: | 2017-04-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Structure of the complex of phosphorylated liver kinase B1 and 14-3-3 zeta Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5WYO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wyo by Molmil](/molmil-images/mine/5wyo) | Solution structure of E.coli HdeA | Descriptor: | Acid stress chaperone HdeA | Authors: | Yang, C, Hu, Y, Jin, C. | Deposit date: | 2017-01-14 | Release date: | 2017-11-22 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Characterizations of the Interactions between Escherichia coli Periplasmic Chaperone HdeA and Its Native Substrates during Acid Stress Biochemistry, 56, 2017
|
|