5M93
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4PG3
| Crystal structure of KRS complexed with inhibitor | Descriptor: | LYSINE, Lysine--tRNA ligase, cladosporin | Authors: | Sharma, A, Yogavel, M, Khan, S, Sharma, A, Belrhali, H. | Deposit date: | 2014-05-01 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin. J. Struct. Funct. Genomics, 15, 2014
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7VC3
| Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and L-proline at 1.97 A resolution | Descriptor: | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CHLORIDE ION, ETHANOLAMINE, ... | Authors: | Malhotra, N, Yogavel, M, Sharma, A. | Deposit date: | 2021-09-01 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.973 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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4AA1
| Crystal structure of ANCE in complex with Angiotensin-II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-2, ANGIOTENSIN-CONVERTING ENZYME, ... | Authors: | Isaac, R.E, Akif, M, Schwager, S.L.U, Masuyer, G, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2011-11-30 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural Basis of Peptide Recognition by the Angiotensin-I Converting Enzyme Homologue Ance from Drosophila Melanogaster FEBS J., 279, 2012
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4AA2
| Crystal structure of ANCE in complex with bradykinin potentiating peptide b | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, BRADYKININ-POTENTIATING PEPTIDE B, ... | Authors: | Isaac, R.E, Akif, M, Schwager, S.L.U, Masuyer, G, Sturrock, E.D, Acharya, K.R. | Deposit date: | 2011-11-30 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural Basis of Peptide Recognition by the Angiotensin-I Converting Enzyme Homologue Ance from Drosophila Melanogaster FEBS J., 279, 2012
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4ASQ
| Crystal structure of ANCE in complex with Bradykinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, BRADYKININ, ... | Authors: | Akif, M, Masuyer, G, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2012-05-02 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural Basis of Peptide Recognition by the Angiotensin-I Converting Enzyme Homologue Ance from Drosophila Melanogaster FEBS J., 279, 2012
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4ASR
| Crystal structure of ANCE in complex with Thr6-Bradykinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, BRADYKININ, ... | Authors: | Akif, M, Masuyer, G, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | Deposit date: | 2012-05-02 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis of Peptide Recognition by the Angiotensin-I Converting Enzyme Homologue Ance from Drosophila Melanogaster FEBS J., 279, 2012
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5X9D
| Crystal structure of homoserine dehydrogenase in complex with L-cysteine and NAD | Descriptor: | (2R)-3-[[(4S)-3-aminocarbonyl-1-[(2R,3R,4S,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4H-pyridin-4-yl]sulfanyl]-2-azanyl-propanoic acid, Homoserine dehydrogenase, L(+)-TARTARIC ACID | Authors: | Goto, M, Ogata, K, Kaneko, R, Yoshimune, K. | Deposit date: | 2017-03-06 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex Sci Rep, 8, 2018
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1IN7
| THERMOTOGA MARITIMA RUVB R170A | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, HOLLIDAY JUNCTION DNA HELICASE RUVB | Authors: | Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A. | Deposit date: | 2001-05-12 | Release date: | 2001-08-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
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1IN6
| THERMOTOGA MARITIMA RUVB K64R MUTANT | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... | Authors: | Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A. | Deposit date: | 2001-05-12 | Release date: | 2001-08-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
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1J7K
| THERMOTOGA MARITIMA RUVB P216G MUTANT | Descriptor: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, COBALT (II) ION, ... | Authors: | Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A. | Deposit date: | 2001-05-16 | Release date: | 2001-08-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
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7FAL
| Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with T36 and L-pro | Descriptor: | 4-[(3R)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, PROLINE, Prolyl-tRNA synthetase (ProRS) | Authors: | Malhotra, N, Mishra, S, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.219 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7FAN
| Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with T35 and L-pro | Descriptor: | 4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, PROLINE, Prolyl-tRNA synthetase (ProRS) | Authors: | Mishra, S, Malhotra, N, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.769 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7FAM
| Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with L97 and L-pro | Descriptor: | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, PROLINE, Prolyl-tRNA synthetase (ProRS) | Authors: | Mishra, S, Malhotra, N, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7FAK
| Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with L96 and L-pro | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, ACETATE ION, ... | Authors: | Malhotra, N, Mishra, S, Yogavel, M, Sharma, A. | Deposit date: | 2021-07-06 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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1IN4
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1IN8
| THERMOTOGA MARITIMA RUVB T158V | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, HOLLIDAY JUNCTION DNA HELICASE RUVB | Authors: | Putnam, C.D, Clancy, S.B, Tsuruta, H, Wetmur, J.G, Tainer, J.A. | Deposit date: | 2001-05-12 | Release date: | 2001-08-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of the RuvB Holliday junction branch migration motor. J.Mol.Biol., 311, 2001
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4XYG
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4XYB
| GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) IN COMPLEX WITH NADP(+) AND NaN3 | Descriptor: | 1,2-ETHANEDIOL, AZIDE ION, Formate dehydrogenase, ... | Authors: | Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. | Deposit date: | 2015-02-02 | Release date: | 2015-07-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
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4XYE
| GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) IN COMPLEX WITH NAD(+) | Descriptor: | Formate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. | Deposit date: | 2015-02-02 | Release date: | 2015-07-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
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3VQJ
| Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase | Descriptor: | Carbonyl sulfide hydrolase, SODIUM ION, ZINC ION | Authors: | Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. | Deposit date: | 2012-03-24 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
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3VRK
| Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase / Thiocyanate complex | Descriptor: | Carbonyl sulfide hydrolase, SODIUM ION, THIOCYANATE ION, ... | Authors: | Katayama, Y, Noguchi, K, Ogawa, T, Ohtaki, A, Odaka, M, Yohda, M. | Deposit date: | 2012-04-11 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the beta-Carbonic Anhydrase Family Enzymes J.Am.Chem.Soc., 135, 2013
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2K85
| p190-A RhoGAP FF1 domain | Descriptor: | Glucocorticoid receptor DNA-binding factor 1 | Authors: | Bonet, R, Ruiz, L, Martin-Malpartida, P, Macias, M. | Deposit date: | 2008-09-02 | Release date: | 2009-05-19 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structural studies on human p190-A RhoGAPFF1 revealed that domain phosphorylation by the PDGF-receptor alpha requires its previous unfolding. J.Mol.Biol., 389, 2009
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2LRQ
| Chemical Shift Assignment and Solution Structure of Fr822A from Drosophila melanogaster. Northeast Structural Genomics Consortium Target Fr822A | Descriptor: | NuA4 complex subunit EAF3 homolog | Authors: | Lee, H, Lee, D, Kohan, E, Janjua, H, Xiao, R, Acton, T, Everett, J.K, Montelione, G, Prestegard, J.H, Northeast Structural Genomics Consortium (NESG), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | Deposit date: | 2012-04-11 | Release date: | 2012-07-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of Fr822A from Drosophila melanogaster. To be Published
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1JNE
| Crystal structure of imaginal disc growth factor-2 | Descriptor: | Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J. | Deposit date: | 2001-07-23 | Release date: | 2002-05-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster. J.Biol.Chem., 277, 2002
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