PDB: 109 resultsInfo pagesStatus searchChemie searchBIRD

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8I1B	A COMPARISON OF THE HIGH RESOLUTION STRUCTURES OF HUMAN AND MURINE INTERLEUKIN-1B Descriptor: INTERLEUKIN-1 BETA Authors: Ohlendorf, D.H, Weber, P.C, Salemme, F.R. Deposit date: 1991-01-29 Release date: 1992-07-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Comparison of the High Resolution Structures of Human and Murine Interleukin-1B To be Published
8J6K	Crystal structure of pro-interleukin-18 and caspase-4 complex Descriptor: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ... Authors: Sun, Q, Hou, Y.J, Ding, J. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.12 Å) Cite: Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature, 624, 2023
8RYK	IL-1beta in complex with macrocyclic peptide hit Descriptor: Interleukin-1 beta, Macrocyclic peptide Authors: Rondeau, J.-M, Lehmann, S. Deposit date: 2024-02-09 Release date: 2024-05-22 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
8RYS	Human IL-1beta, unliganded Descriptor: Interleukin-1 beta, SULFATE ION Authors: Rondeau, J.-M, Lehmann, S. Deposit date: 2024-02-09 Release date: 2024-03-06 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.16 Å) Cite: Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
8RZB	IL-1beta in complex with covalent DEL hit Descriptor: 8-[4-methyl-3-(trifluoromethyl)phenyl]-2-[[(7S)-7-(2-morpholin-4-ylethylcarbamoyl)-4-(phenylsulfonyl)-1,4-diazepan-1-yl]carbonyl]imidazo[1,2-a]pyridine-6-carboxylic acid, Interleukin-1 beta Authors: Rondeau, J.-M, Lehmann, S. Deposit date: 2024-02-12 Release date: 2024-05-22 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.836 Å) Cite: Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
8SPB	Caspase-4/Pro-IL-18 complex Descriptor: Caspase-4 subunit p10, Caspase-4 subunit p20, Interleukin-18 Authors: Pascal, D, Dong, Y, Wu, H, Jon, K. Deposit date: 2023-05-02 Release date: 2023-11-22 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into cytokine cleavage by inflammatory caspase-4. Nature, 624, 2023
8SV1	Caspase-1 complex with interleukin-18 Descriptor: Caspase-1, Interleukin-18 Authors: Dong, Y, Pascal, D, Jon, K, Wu, H. Deposit date: 2023-05-15 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Caspase-1 complex with interleukin-18 To Be Published
8URV	Solution NMR structure of pro-IL-18 Descriptor: Interleukin-18 Authors: Bonin, J.P, Aramini, J.M, Kay, L.E. Deposit date: 2023-10-26 Release date: 2024-05-29 Method: SOLUTION NMR Cite: Structural transitions enable interleukin-18 maturation and signaling. Immunity, 2024
9ILB	HUMAN INTERLEUKIN-1 BETA Descriptor: PROTEIN (HUMAN INTERLEUKIN-1 BETA) Authors: Yu, B, Blaber, M, Gronenborn, A.M, Clore, G.M, Caspar, D.L.D. Deposit date: 1998-10-22 Release date: 1999-01-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography. Proc.Natl.Acad.Sci.USA, 96, 1999

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