7TRF
 
 | | Human telomerase catalytic core RNP with H2A/H2B | | Descriptor: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | | Deposit date: | 2022-01-28 | | Release date: | 2022-04-20 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
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7UIM
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7UIN
 | | CryoEM Structure of an Group II Intron Retroelement | | Descriptor: | AMMONIUM ION, DNA (37-MER), E.r IIC Intron, ... | | Authors: | Chung, K, Xu, L. | | Deposit date: | 2022-03-29 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structures of a mobile intron retroelement poised to attack its structured DNA target
Science, 378, 2022
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7TRD
 | | Human telomerase catalytic core structure at 3.3 Angstrom | | Descriptor: | Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ... | | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | | Deposit date: | 2022-01-28 | | Release date: | 2022-04-20 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
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7V99
 | | catalytic core of human telomerase holoenzyme | | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ... | | Authors: | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | | Deposit date: | 2021-08-24 | | Release date: | 2022-03-30 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
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3KYL
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6AR3
 | | Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Se-Met)) | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... | | Authors: | Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. | | Deposit date: | 2017-08-21 | | Release date: | 2017-11-29 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications.
Mol. Cell, 68, 2017
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6AR1
 | | Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Nat)) | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... | | Authors: | Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. | | Deposit date: | 2017-08-21 | | Release date: | 2017-11-29 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications.
Mol. Cell, 68, 2017
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8SXU
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8SXT
 | | Structure of LINE-1 ORF2p with template:primer hybrid | | Descriptor: | DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | | Authors: | van Eeuwen, T, Taylor, M.S, Rout, M.P. | | Deposit date: | 2023-05-24 | | Release date: | 2024-01-10 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
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8T2T
 | | Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state | | Descriptor: | AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ... | | Authors: | Xu, L, Liu, T, Chung, K, Pyle, A.M. | | Deposit date: | 2023-06-06 | | Release date: | 2023-11-22 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
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8T2R
 | | Structure of a group II intron ribonucleoprotein in the pre-ligation (pre-2F) state | | Descriptor: | 5'exon, AMMONIUM ION, CALCIUM ION, ... | | Authors: | Xu, L, Liu, T, Chung, K, Pyle, A.M. | | Deposit date: | 2023-06-06 | | Release date: | 2023-11-22 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
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8T2S
 | | Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state | | Descriptor: | AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ... | | Authors: | Xu, L, Liu, T, Chung, K, Pyle, A.M. | | Deposit date: | 2023-06-06 | | Release date: | 2023-11-22 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
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8TCK
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8TCL
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8TCJ
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8TCM
 | | Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and Xanthene-1,3,6,8-tetrol bound | | Descriptor: | 9H-xanthene-1,3,6,8-tetrol, PICRIC ACID, p51 subunit | | Authors: | Pedersen, L.C, London, R.E. | | Deposit date: | 2023-07-02 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and xanthene bound
To Be Published
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8UBB
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8UW3
 | | Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state | | Descriptor: | Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E. | | Deposit date: | 2023-11-06 | | Release date: | 2023-12-20 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Template and target-site recognition by human LINE-1 in retrotransposition.
Nature, 626, 2024
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8UBF
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8UB9
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8UBA
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8UB8
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8UBC
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8UB7
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