7YKT
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![BU of 7ykt by Molmil](/molmil-images/mine/7ykt) | Cryo-EM structure of Drg1 hexamer in helical state treated with ADP/AMPPNP/benzo-diazaborine | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family gene 2 protein | Authors: | Ma, C.Y, Wu, D.M, Chen, Q, Gao, N. | Deposit date: | 2022-07-23 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition. Nat Commun, 13, 2022
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8DAR
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![BU of 8dar by Molmil](/molmil-images/mine/8dar) | |
8DAU
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![BU of 8dau by Molmil](/molmil-images/mine/8dau) | |
8DAW
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![BU of 8daw by Molmil](/molmil-images/mine/8daw) | |
8DAS
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![BU of 8das by Molmil](/molmil-images/mine/8das) | |
8DAT
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![BU of 8dat by Molmil](/molmil-images/mine/8dat) | |
8DAV
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![BU of 8dav by Molmil](/molmil-images/mine/8dav) | |
7TFL
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![BU of 7tfl by Molmil](/molmil-images/mine/7tfl) | Atomic model of S. cerevisiae clamp loader RFC bound to DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2022-01-06 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
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7TFI
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![BU of 7tfi by Molmil](/molmil-images/mine/7tfi) | Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2022-01-06 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
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7TFK
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![BU of 7tfk by Molmil](/molmil-images/mine/7tfk) | Atomic model of S. cerevisiae clamp loader RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2022-01-06 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
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7TFJ
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![BU of 7tfj by Molmil](/molmil-images/mine/7tfj) | Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2022-01-06 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
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7TFH
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![BU of 7tfh by Molmil](/molmil-images/mine/7tfh) | Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2022-01-06 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
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7UIX
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![BU of 7uix by Molmil](/molmil-images/mine/7uix) | ClpAP complex bound to ClpS N-terminal extension, class I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIW
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![BU of 7uiw by Molmil](/molmil-images/mine/7uiw) | ClpAP complex bound to ClpS N-terminal extension, class IIb | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIZ
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![BU of 7uiz by Molmil](/molmil-images/mine/7uiz) | ClpAP complex bound to ClpS N-terminal extension, class IIc | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIV
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![BU of 7uiv by Molmil](/molmil-images/mine/7uiv) | ClpAP complex bound to ClpS N-terminal extension, class IIa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UJ0
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![BU of 7uj0 by Molmil](/molmil-images/mine/7uj0) | ClpAP complex bound to ClpS N-terminal extension, class IIIb | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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8CVT
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![BU of 8cvt by Molmil](/molmil-images/mine/8cvt) | Human 19S-20S proteasome, state SD2 | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | Authors: | Zhao, J. | Deposit date: | 2022-05-18 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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7UIY
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![BU of 7uiy by Molmil](/molmil-images/mine/7uiy) | ClpAP complex bound to ClpS N-terminal extension, class IIIa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-10-26 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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8A8V
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![BU of 8a8v by Molmil](/molmil-images/mine/8a8v) | Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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8A8U
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![BU of 8a8u by Molmil](/molmil-images/mine/8a8u) | Mycobacterium tuberculosis ClpC1 hexamer structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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8A8W
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![BU of 8a8w by Molmil](/molmil-images/mine/8a8w) | Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (4.29 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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7W46
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![BU of 7w46 by Molmil](/molmil-images/mine/7w46) | Crystal structure of Bacillus subtilis YjoB with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Uncharacterized ATPase YjoB | Authors: | Dahal, P, Kwon, E, Kim, D.Y. | Deposit date: | 2021-11-26 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and biochemical analysis suggest that YjoB ATPase is a putative substrate-specific molecular chaperone. Proc.Natl.Acad.Sci.USA, 119, 2022
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7WTL
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![BU of 7wtl by Molmil](/molmil-images/mine/7wtl) | Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Dis-D | Descriptor: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | Authors: | Cheng, J, La Venuta, G, Lau, B, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2022-02-05 | Release date: | 2022-10-19 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation. Nucleic Acids Res., 50, 2022
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7W42
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![BU of 7w42 by Molmil](/molmil-images/mine/7w42) | Crystal structure of Bacillus subtilis YjoB | Descriptor: | Uncharacterized ATPase YjoB | Authors: | Dahal, P, Kwon, E, Kim, D.Y. | Deposit date: | 2021-11-26 | Release date: | 2022-10-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.619 Å) | Cite: | Crystal structure and biochemical analysis suggest that YjoB ATPase is a putative substrate-specific molecular chaperone. Proc.Natl.Acad.Sci.USA, 119, 2022
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