7TFK

Atomic model of S. cerevisiae clamp loader RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end

Summary for 7TFK

• Entry DOI: 10.2210/pdb7tfk/pdb
• EMDB information: 25872 25873 25874 25875 25876
• Descriptor: Replication factor C subunit 1, ADENOSINE-5'-DIPHOSPHATE, Replication factor C subunit 4, ... (10 entities in total)
• Functional Keywords: dna replication, dna damage repair, rfc loader, pcna clamp, dna polymerase processivity factor, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 9
• Total formula weight: 288610.89

Authors

Zheng, F.,Georgescu, R.,Yao, Y.N.,O'Donnell, M.E.,Li, H. (deposition date: 2022-01-06, release date: 2022-11-16)

• Primary citation: Zheng, F.,Georgescu, R.,Yao, N.Y.,Li, H.,O'Donnell, M.E.; Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.; Elife, 11:-, 2022; PubMed: 35829698; DOI: 10.7554/eLife.77469

Experimental method

ELECTRON MICROSCOPY (3.25 Å)