7TFK

Atomic model of S. cerevisiae clamp loader RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000278	biological_process	mitotic cell cycle
A	0003677	molecular_function	DNA binding
A	0003689	molecular_function	DNA clamp loader activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005663	cellular_component	DNA replication factor C complex
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0006272	biological_process	leading strand elongation
A	0006281	biological_process	DNA repair
A	0006298	biological_process	mismatch repair
A	0016887	molecular_function	ATP hydrolysis activity
A	0051301	biological_process	cell division
B	0000077	biological_process	DNA damage checkpoint signaling
B	0003677	molecular_function	DNA binding
B	0003689	molecular_function	DNA clamp loader activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005663	cellular_component	DNA replication factor C complex
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0006272	biological_process	leading strand elongation
B	0006281	biological_process	DNA repair
B	0007062	biological_process	sister chromatid cohesion
B	0007064	biological_process	mitotic sister chromatid cohesion
B	0016887	molecular_function	ATP hydrolysis activity
B	0031389	cellular_component	Rad17 RFC-like complex
B	0031390	cellular_component	Ctf18 RFC-like complex
B	0031391	cellular_component	Elg1 RFC-like complex
B	0090618	biological_process	DNA clamp unloading
C	0000077	biological_process	DNA damage checkpoint signaling
C	0003677	molecular_function	DNA binding
C	0003689	molecular_function	DNA clamp loader activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005663	cellular_component	DNA replication factor C complex
C	0005829	cellular_component	cytosol
C	0006260	biological_process	DNA replication
C	0006261	biological_process	DNA-templated DNA replication
C	0006271	biological_process	DNA strand elongation involved in DNA replication
C	0006272	biological_process	leading strand elongation
C	0006281	biological_process	DNA repair
C	0006298	biological_process	mismatch repair
C	0007064	biological_process	mitotic sister chromatid cohesion
C	0016887	molecular_function	ATP hydrolysis activity
C	0031389	cellular_component	Rad17 RFC-like complex
C	0031390	cellular_component	Ctf18 RFC-like complex
C	0031391	cellular_component	Elg1 RFC-like complex
C	0090618	biological_process	DNA clamp unloading
D	0000076	biological_process	DNA replication checkpoint signaling
D	0000077	biological_process	DNA damage checkpoint signaling
D	0003677	molecular_function	DNA binding
D	0003689	molecular_function	DNA clamp loader activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005663	cellular_component	DNA replication factor C complex
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006271	biological_process	DNA strand elongation involved in DNA replication
D	0006272	biological_process	leading strand elongation
D	0006281	biological_process	DNA repair
D	0006298	biological_process	mismatch repair
D	0007062	biological_process	sister chromatid cohesion
D	0007064	biological_process	mitotic sister chromatid cohesion
D	0016887	molecular_function	ATP hydrolysis activity
D	0031389	cellular_component	Rad17 RFC-like complex
D	0031390	cellular_component	Ctf18 RFC-like complex
D	0031391	cellular_component	Elg1 RFC-like complex
D	0090618	biological_process	DNA clamp unloading
E	0000077	biological_process	DNA damage checkpoint signaling
E	0003677	molecular_function	DNA binding
E	0003689	molecular_function	DNA clamp loader activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005663	cellular_component	DNA replication factor C complex
E	0006260	biological_process	DNA replication
E	0006261	biological_process	DNA-templated DNA replication
E	0006271	biological_process	DNA strand elongation involved in DNA replication
E	0006272	biological_process	leading strand elongation
E	0006281	biological_process	DNA repair
E	0007062	biological_process	sister chromatid cohesion
E	0007064	biological_process	mitotic sister chromatid cohesion
E	0016887	molecular_function	ATP hydrolysis activity
E	0031389	cellular_component	Rad17 RFC-like complex
E	0031390	cellular_component	Ctf18 RFC-like complex
E	0031391	cellular_component	Elg1 RFC-like complex
E	0090618	biological_process	DNA clamp unloading

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
E	VAL5
E	SER17
E	GLY43
E	ARG231
D	ARG229
C	ARG206

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
D	MET1

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	SER40

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	THR63

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