7OZP
| RNA Polymerase II dimer (Class 3) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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7OZO
| RNA Polymerase II dimer (Class 2) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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7OZN
| RNA Polymerase II dimer (Class 1) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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5EJK
| Crystal structure of the Rous sarcoma virus intasome | Descriptor: | DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*TP*AP*CP*TP*C)-3'), DNA (5'-D(*AP*GP*TP*GP*TP*CP*TP*T)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*CP*TP*C)-3'), ... | Authors: | Yin, Z, Shi, K, Banerjee, S, Aihara, H. | Deposit date: | 2015-11-02 | Release date: | 2016-02-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal structure of the Rous sarcoma virus intasome. Nature, 530, 2016
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5LEJ
| The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | Descriptor: | DNA (30-MER), Listeriolysin regulatory protein | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-06-29 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5LRS
| The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30-bp operator PrfA-box motif | Descriptor: | DNA (30-MER), GLUTATHIONE, Listeriolysin positive regulatory factor A | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-08-19 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6UU0
| E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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8U3B
| Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A | Descriptor: | DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Liu, B, Kompaniiets, D, Wang, D. | Deposit date: | 2023-09-07 | Release date: | 2024-01-17 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural basis for transcription activation by the nitrate-responsive regulator NarL. Nucleic Acids Res., 52, 2024
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5DUI
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6TYE
| Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Molodtsov, V, Ebright, R.H. | Deposit date: | 2019-08-08 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.79 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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8TVP
| Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVV
| Cryo-EM structure of backtracked Pol II | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVX
| Cryo-EM structure of CPD-stalled Pol II (Conformation 2) | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVY
| Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVW
| Cryo-EM structure of CPD-stalled Pol II (conformation 1) | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVS
| Cryo-EM structure of backtracked Pol II in complex with Rad26 | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TUG
| Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) | Descriptor: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-16 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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6KOP
| Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt | Descriptor: | DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Li, L, Zhang, Y. | Deposit date: | 2019-08-12 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.303 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KOQ
| Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 10 nt | Descriptor: | DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Li, L, Zhang, Y. | Deposit date: | 2019-08-12 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.353 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KON
| Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt | Descriptor: | DNA (5'-D(P*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Li, L, Zhang, Y. | Deposit date: | 2019-08-12 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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3T79
| Ndc10: a platform for inner kinetochore assembly in budding yeast | Descriptor: | DNA (5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*AP*TP*AP*AP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*TP*TP*TP*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*TP*TP*TP*AP*TP*AP*AP*AP*AP*TP*T)-3'), ... | Authors: | Cho, U.S, Harrison, S.C. | Deposit date: | 2011-07-29 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.6113 Å) | Cite: | Ndc10 is a platform for inner kinetochore assembly in budding yeast. Nat.Struct.Mol.Biol., 19, 2011
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6KOO
| Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt | Descriptor: | DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Li, L, Zhang, Y. | Deposit date: | 2019-08-12 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6DVC
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Lin, W, Das, K, Feng, Y, Ebright, R.H. | Deposit date: | 2018-06-23 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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6KQE
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 4 nt | Descriptor: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Zhang, Y, Li, L, Ebright, R.H. | Deposit date: | 2019-08-17 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQM
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 5 nt | Descriptor: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Zhang, Y, Li, L, Ebright, R.H. | Deposit date: | 2019-08-18 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.197 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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