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3C90
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BU of 3c90 by Molmil
The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II
Descriptor: Phosphoribosyl-ATP pyrophosphatase
Authors:Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2008-02-14
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
3L9P
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BU of 3l9p by Molmil
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
Descriptor: Anaplastic lymphoma kinase, GLYCEROL
Authors:Lee, C.
Deposit date:2010-01-05
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
3LK3
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BU of 3lk3 by Molmil
Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, Leucine-rich repeat-containing protein 16A
Authors:Hernandez-Valladares, M, Kim, T, Kannan, B, Tung, A, Cooper, J.A, Robinson, R.C.
Deposit date:2010-01-27
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural characterization of a capping protein interaction motif defines a family of actin filament regulators.
Nat.Struct.Mol.Biol., 17, 2010
3CQF
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BU of 3cqf by Molmil
Crystal structure of anthrolysin O (ALO)
Descriptor: Thiol-activated cytolysin
Authors:Bourdeau, R.W, Malito, E, Tang, W.J.
Deposit date:2008-04-02
Release date:2009-03-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis
J.Biol.Chem., 284, 2009
3MGI
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BU of 3mgi by Molmil
Ternary complex of a DNA polymerase lambda loop mutant
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA, DNA (5'-D(*CP*AP*GP*TP*AP*T)-3'), ...
Authors:Garcia-Diaz, M, Bebenek, K, Zhou, R.Z, Povirk, L.F, Kunkel, T.
Deposit date:2010-04-06
Release date:2010-05-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Loop 1 modulates the fidelity of DNA polymerase lambda
Nucleic Acids Res., 38, 2010
3M37
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BU of 3m37 by Molmil
Factor XA in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC602)
Descriptor: 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Coagulation factor X
Authors:Alexander, R.S.
Deposit date:2010-03-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor.
J.Med.Chem., 46, 2003
3ML4
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BU of 3ml4 by Molmil
Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region
Descriptor: Muscle, skeletal receptor tyrosine-protein kinase, Protein Dok-7
Authors:Bergamin, E, Hubbard, S.R.
Deposit date:2010-04-16
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
Mol.Cell, 39, 2010
3EAR
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BU of 3ear by Molmil
Novel dimerization motif in the DEAD box RNA helicase Hera: form 1, partial dimer
Descriptor: Hera
Authors:Klostermeier, D, Rudolph, M.G.
Deposit date:2008-08-26
Release date:2008-12-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility.
Nucleic Acids Res., 37, 2009
3NF3
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BU of 3nf3 by Molmil
Crystal structure of BoNT/A LC with JTH-NB-7239 peptide
Descriptor: BoNT/A, JTH-NB72-39 inhibitor, NICKEL (II) ION, ...
Authors:Zuniga, J.E.
Deposit date:2010-06-09
Release date:2010-07-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A.
Plos One, 5, 2010
3EPE
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BU of 3epe by Molmil
Crystal Structure of the GluR4 Ligand-Binding domain in complex with glutamate
Descriptor: GLUTAMIC ACID, Glutamate receptor 4,Glutamate receptor
Authors:Gill, A, Madden, D.R.
Deposit date:2008-09-29
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
3N2G
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BU of 3n2g by Molmil
TUBULIN-NSC 613863: RB3 Stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
Deposit date:2010-05-18
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
3NBI
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BU of 3nbi by Molmil
Crystal structure of human RMI1 N-terminus
Descriptor: RecQ-mediated genome instability protein 1
Authors:Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
3MPP
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BU of 3mpp by Molmil
Botulinum Neurotoxin Type G Receptor Binding Domain
Descriptor: Botulinum neurotoxin type G
Authors:Schmitt, J.M, Lacy, D.B.
Deposit date:2010-04-27
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural analysis of botulinum neurotoxin type G receptor binding .
Biochemistry, 49, 2010
3E5X
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BU of 3e5x by Molmil
OCPA complexed CprK
Descriptor: (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, Cyclic nucleotide-binding protein
Authors:Levy, C.
Deposit date:2008-08-14
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator
Mol.Microbiol., 70, 2008
3EAS
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BU of 3eas by Molmil
Novel dimerization motif in the DEAD box RNA helicase Hera: form 1, complete dimer, asymmetric
Descriptor: Hera
Authors:Klostermeier, D, Rudolph, M.G.
Deposit date:2008-08-26
Release date:2008-12-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility.
Nucleic Acids Res., 37, 2009
3ERK
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BU of 3erk by Molmil
THE COMPLEX STRUCTURE OF THE MAP KINASE ERK2/SB220025
Descriptor: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, EXTRACELLULAR REGULATED KINASE 2
Authors:Wang, Z, Canagarajah, B, Boehm, J.C, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
Deposit date:1998-07-09
Release date:1999-07-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
3MVT
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BU of 3mvt by Molmil
Crystal structure of apo mADA at 2.2A resolution
Descriptor: Adenosine deaminase, CHLORIDE ION, GLYCEROL
Authors:Niu, W, Shu, Q, Chen, Z, Mathews, S, Di Cera, E, Frieden, C.
Deposit date:2010-05-04
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The role of Zn2+ on the structure and stability of murine adenosine deaminase.
J.Phys.Chem.B, 114, 2010
3MXN
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BU of 3mxn by Molmil
Crystal structure of the RMI core complex
Descriptor: BENZAMIDINE, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2
Authors:Hoadley, K.A, Xu, D, Xue, Y, Satyshur, K.A, Wang, W, Keck, J.L.
Deposit date:2010-05-07
Release date:2010-09-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome.
Structure, 18, 2010
3NKE
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BU of 3nke by Molmil
High resolution structure of the C-terminal domain CRISP-associated protein Cas1 from Escherichia coli str. K-12
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, SULFITE ION, ...
Authors:Nocek, B, Skarina, T, Beloglazova, N, Savchenko, A, Joachimiak, A, Yakunin, A.
Deposit date:2010-06-18
Release date:2010-08-25
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Mol.Microbiol., 79, 2011
3NB6
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BU of 3nb6 by Molmil
Crystal structure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin
Descriptor: Penicillin-binding protein 1A
Authors:Sliz, P, Yuan, Y, Walker, S, Kahne, D.
Deposit date:2010-06-02
Release date:2011-05-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.
Acs Chem.Biol., 5, 2010
3NFZ
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BU of 3nfz by Molmil
Crystal structure of murine aminoacylase 3 in complex with N-acetyl-L-tyrosine
Descriptor: Aspartoacylase-2, CHLORIDE ION, N-acetyl-L-tyrosine, ...
Authors:Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A.
Deposit date:2010-06-10
Release date:2010-10-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.147 Å)
Cite:Structures of aminoacylase 3 in complex with acetylated substrates.
Proc.Natl.Acad.Sci.USA, 107, 2010
3NB7
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BU of 3nb7 by Molmil
Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin
Descriptor: Penicillin-binding protein 1A
Authors:Sliz, P, Yuan, Y, Walker, S.
Deposit date:2010-06-02
Release date:2011-05-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.
Acs Chem.Biol., 5, 2010
3NBH
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BU of 3nbh by Molmil
Crystal structure of human RMI1C-RMI2 complex
Descriptor: RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2
Authors:Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
3NWQ
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X-ray structure of ester chemical analogue [O-Ile50,O-Ile50']HIV-1 protease complexed with MVT-101
Descriptor: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, protease
Authors:Torbeev, V.Y, Kent, S.B.H.
Deposit date:2010-07-10
Release date:2011-11-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
7LAF
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BU of 7laf by Molmil
15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor
Descriptor: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B
Authors:Newcomer, M.E, Gilbert, N.C, Neau, D.B.
Deposit date:2021-01-06
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg.Med.Chem., 46, 2021

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