2GCF
| Solution structure of the N-terminal domain of the coppper(I) ATPase PacS in its apo form | Descriptor: | Cation-transporting ATPase pacS | Authors: | Banci, L, Bertini, I, Ciofi-Baffoni, S, Kandias, N.G, Spyroulias, G.A, Robinson, N.J, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-03-14 | Release date: | 2006-05-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The delivery of copper for thylakoid import observed by NMR. Proc.Natl.Acad.Sci.Usa, 103, 2006
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5IH5
| Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A | Descriptor: | 6-(3-chlorophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ... | Authors: | Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. | Deposit date: | 2016-02-29 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
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2GD7
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7RWE
| Crystal structure of CDK2 liganded with compound GPHR787 | Descriptor: | 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid, Cyclin-dependent kinase 2 | Authors: | Sun, L, Schonbrunn, E. | Deposit date: | 2021-08-19 | Release date: | 2022-08-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. J.Med.Chem., 66, 2023
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5IHC
| MELK in complex with NVS-MELK12B | Descriptor: | 4-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]-3-[(piperidin-4-yl)methoxy]pyridine, Maternal embryonic leucine zipper kinase | Authors: | Sprague, E.R, Brazell, T. | Deposit date: | 2016-02-29 | Release date: | 2016-06-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J.Med.Chem., 59, 2016
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2ROK
| Solution structure of the cap-binding domain of PARN complexed with the cap analog | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, poly(A)-specific ribonuclease | Authors: | Nagata, T, Suzuki, S, Endo, R, Shirouzu, M, Terada, T, Inoue, M, Kigawa, T, Guntert, P, Hayashizaki, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-03-28 | Release date: | 2009-02-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition. Nucleic Acids Res., 36, 2008
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5IBN
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2RP3
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7RVI
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2GGZ
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7RV8
| Crystal structure of the BCL6 BTB domain in complex with OICR-10268 | Descriptor: | DIMETHYL SULFOXIDE, Isoform 2 of B-cell lymphoma 6 protein, N-[5-chloro-2-(morpholin-4-yl)pyridin-4-yl]-2-{5-(3-cyano-4-hydroxy-5-methylphenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide | Authors: | Kuntz, D.A, Prive, G.G. | Deposit date: | 2021-08-18 | Release date: | 2022-08-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure of the BCL6 BTB domain To Be Published
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2RPN
| A crucial role for high intrinsic specificity in the function of yeast SH3 domains | Descriptor: | Actin-binding protein, Actin-regulating kinase 1 | Authors: | Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A. | Deposit date: | 2008-06-12 | Release date: | 2009-06-16 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J.Biol.Chem., 284, 2009
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2GHT
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2RO8
| Solution structure of calcium bound soybean calmodulin isoform 1 N-terminal domain | Descriptor: | CALCIUM ION, Calmodulin | Authors: | Ishida, H, Huang, H, Yamniuk, A.P, Takaya, Y, Vogel, H.J. | Deposit date: | 2008-03-14 | Release date: | 2008-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structures of two soybean calmodulin isoforms provide a structural basis for their selective target activation properties J.Biol.Chem., 283, 2008
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2GIB
| Crystal structure of the SARS coronavirus nucleocapsid protein dimerization domain | Descriptor: | Nucleocapsid protein, SULFATE ION | Authors: | Yu, I.M, Oldham, M.L, Zhang, J, Chen, J. | Deposit date: | 2006-03-28 | Release date: | 2006-04-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between corona- and arteriviridae. J.Biol.Chem., 281, 2006
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7RVL
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5ICH
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2RQ4
| Refinement of RNA binding domain 3 in CUG triplet repeat RNA-binding protein 1 | Descriptor: | CUG-BP- and ETR-3-like factor 1 | Authors: | Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Inoue, M, Terada, T, Kobayashi, N, Shirouzu, M, Kigawa, T, Guntert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-01-19 | Release date: | 2009-08-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 Nucleic Acids Res., 2009
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2FVX
| CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57T REDUCED (277K) | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | Deposit date: | 1996-12-19 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
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2ROL
| Structural Basis of PxxDY motif recognition in SH3 binding | Descriptor: | 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain, Epidermal growth factor receptor kinase substrate 8-like protein 1 | Authors: | Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Paakkonen, K, Saksela, K, Permi, P. | Deposit date: | 2008-04-02 | Release date: | 2009-03-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of PxxDY motif recognition in SH3 binding J.Mol.Biol., 382, 2008
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5IJ6
| Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-1) in complex with lipoic acid | Descriptor: | CHLORIDE ION, LIPOIC ACID, Lipoate--protein ligase, ... | Authors: | Hughes, S.J, Lyle, A.G, Song, J.H, Antoshchenko, T, Park, H. | Deposit date: | 2016-03-01 | Release date: | 2017-03-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-1) in complex with lipoic acid to be published
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2FMR
| KH1 FROM THE FRAGILE X PROTEIN FMR1, NMR, 18 STRUCTURES | Descriptor: | FMR1 PROTEIN | Authors: | Musco, G, Kharrat, A, Stier, G, Fraternali, F, Gibson, T.J, Nilges, M, Pastore, A. | Deposit date: | 1997-10-06 | Release date: | 1998-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome. Nat.Struct.Biol., 4, 1997
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2RQQ
| Structure of C-terminal region of Cdt1 | Descriptor: | DNA replication factor Cdt1 | Authors: | Jee, J.G, Mizuno, T, Kamada, K, Tochio, H, Hiroaki, H, Hanaoka, F, Shirakawa, M. | Deposit date: | 2009-10-14 | Release date: | 2010-03-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins J.Biol.Chem., 285, 2010
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5IJG
| Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution | Descriptor: | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE | Authors: | Boyko, K.M, Nikolaeva, A.Y, Koolikova, V.V, Kotlov, M.I, Demidkina, T.V, Popov, V.O. | Deposit date: | 2016-03-02 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution To Be Published
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2FOW
| THE RNA BINDING DOMAIN OF RIBOSOMAL PROTEIN L11: THREE-DIMENSIONAL STRUCTURE OF THE RNA-BOUND FORM OF THE PROTEIN, NMR, 26 STRUCTURES | Descriptor: | RIBOSOMAL PROTEIN L11 | Authors: | Hinck, A.P, Markus, M.A, Huang, S, Grzesiek, S, Kustanovich, I, Draper, D.E, Torchia, D.A. | Deposit date: | 1997-05-26 | Release date: | 1997-11-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The RNA binding domain of ribosomal protein L11: three-dimensional structure of the RNA-bound form of the protein and its interaction with 23 S rRNA. J.Mol.Biol., 274, 1997
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