PDB: 105044 resultsInfo pagesStatus searchChemie searchBIRD

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4J9H	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH 8 Descriptor: P7, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
6SDM	NADH-dependent variant of TBADH Descriptor: NADP-dependent isopropanol dehydrogenase, ZINC ION Authors: Selles Vidal, L, Murray, J.W, Heap, J.T. Deposit date: 2019-07-28 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Versatile selective evolutionary pressure using synthetic defect in universal metabolism. Nat Commun, 12, 2021
6HEQ	Prion nanobody 484 Descriptor: Prion nanobody 484 Authors: Soror, S.H, Abskharon, R.N, Wohlkonig, A. Deposit date: 2018-08-20 Release date: 2019-12-04 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion. Plos Pathog., 15, 2019
6SCW	SH3-subunit of chicken alpha spectrin solved by NMR Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11 Authors: Grohe, K, Hebrank, C, Linser, R. Deposit date: 2019-07-25 Release date: 2020-08-12 Last modified: 2024-01-31 Method: SOLUTION NMR Cite: Protein Motional Details Revealed by Complementary Structural Biology Techniques. Structure, 28, 2020
6HF2	The structure of BoMan26B, a GH26 beta-mannanase from Bacteroides ovatus Descriptor: CALCIUM ION, CHLORIDE ION, Glycosyl hydrolase family 26 Authors: Bagenholm, V, Logan, D.T, Stalbrand, H. Deposit date: 2018-08-21 Release date: 2019-04-24 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.69 Å) Cite: A surface-exposed GH26 beta-mannanase fromBacteroides ovatus: Structure, role, and phylogenetic analysis ofBoMan26B. J.Biol.Chem., 294, 2019
6HF4	The structure of BoMan26B, a GH26 beta-mannanase from Bacteroides ovatus, complexed with G1M4 Descriptor: CALCIUM ION, CHLORIDE ION, Glycosyl hydrolase family 26, ... Authors: Bagenholm, V, Logan, D.T, Stalbrand, H. Deposit date: 2018-08-21 Release date: 2019-04-24 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.781 Å) Cite: A surface-exposed GH26 beta-mannanase fromBacteroides ovatus: Structure, role, and phylogenetic analysis ofBoMan26B. J.Biol.Chem., 294, 2019
8S84	KOD-H4 DNA polymerase mutant in a ternary complex with DNA/DNA and non-hydrolyzable triphosphate Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*CP*A*(XG4))-3'), DNA (5'-D(P*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... Authors: Gutfreund, C, Betz, K. Deposit date: 2024-03-05 Release date: 2024-11-13 Last modified: 2025-01-22 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural insights into a DNA polymerase reading the xeno nucleic acid HNA. Nucleic Acids Res., 53, 2025
6IPX	Crystal structure of the apo form transcription factor Descriptor: AimR transcriptional regulator Authors: Oy, S.Y, Zhen, X, Zhou, H, Ding, W. Deposit date: 2018-11-05 Release date: 2019-01-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.634 Å) Cite: Structural basis of AimP signaling molecule recognition by AimR in Spbeta group of bacteriophages. Protein Cell, 10, 2019
7QDU	Twist-corrected RNA origami 5-helix Tile A Descriptor: Chains: Q Authors: McRae, E.K.S, Andersen, E.S. Deposit date: 2021-11-30 Release date: 2022-12-14 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (5.14 Å) Cite: Structure, folding and flexibility of co-transcriptional RNA origami. Nat Nanotechnol, 18, 2023
7QDL	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 with I-BET567 Descriptor: (2S,4R)-1-acetyl-4-((5-chloropyrimidin-2-yl)amino)-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 Authors: Chung, C. Deposit date: 2021-11-27 Release date: 2022-12-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate. J.Med.Chem., 65, 2022
6IS8	Crystal structure of ZmMoc1 D115N mutant in complex with Holliday junction Descriptor: DNA (33-MER), MAGNESIUM ION, Monokaryotic chloroplast 1, ... Authors: Lin, Z, Lin, H, Zhang, D, Yuan, C. Deposit date: 2018-11-15 Release date: 2019-10-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
8S7H	Fructose 6-phosphate aldolase (FSA) from Escherichia coli Descriptor: Fructose-6-phosphate aldolase 1 Authors: Hebert, H, Widersten, M. Deposit date: 2024-03-01 Release date: 2025-03-12 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: The Structure of an Engineered Aldolase Catalyzing Carboligation of Arylated Ketones and Aldehydes, Capturing the Iminium Reaction Intermediate, Points Towards a Conserved Tyrosine Residue as Catalytic Acid/Base To Be Published
8S7I	Fructose 6-phosphate aldolase, L107C/A129G/R134V/L163C/S166G mutant Descriptor: Fructose-6-phosphate aldolase 1 Authors: Hebert, H, Widersten, M. Deposit date: 2024-03-01 Release date: 2025-03-12 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The Structure of an Engineered Aldolase Catalyzing Carboligation of Arylated Ketones and Aldehydes, Capturing the Iminium Reaction Intermediate, Points Towards a Conserved Tyrosine Residue as Catalytic Acid/Base To Be Published
5OQ7	Structure of CHK1 8-pt. mutant complex with arylbenzamide LRRK2 inhibitor Descriptor: 5-(4-methylpiperazin-1-yl)-2-phenylmethoxy-~{N}-pyridin-3-yl-benzamide, Serine/threonine-protein kinase Chk1 Authors: Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. Deposit date: 2017-08-10 Release date: 2017-10-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1). J. Med. Chem., 60, 2017
6JKC	Crystal structure of tetrameric PepTSo2 in P4212 space group Descriptor: Proton:oligopeptide symporter POT family Authors: Nagamura, R, Fukuda, M, Ishitani, R, Nureki, O. Deposit date: 2019-02-28 Release date: 2019-05-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2. Acta Crystallogr.,Sect.F, 75, 2019
6JRF	Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium Descriptor: CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ... Authors: Lin, Z, Lin, H, Zhang, D, Yuan, C. Deposit date: 2019-04-03 Release date: 2019-10-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.047 Å) Cite: Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
8R4I	Cryo-EM structure of human islet amyloid polypeptide (hIAPP) Descriptor: Islet amyloid polypeptide Authors: Ooi, S.A, Valli, D, Maj, M. Deposit date: 2023-11-13 Release date: 2024-03-06 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (4.01 Å) Cite: Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins. Biophys.J., 123, 2024
1XC6	Native Structure Of Beta-Galactosidase from Penicillium sp. in complex with Galactose Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Rojas, A.L, Nagem, R.A.P, Neustroev, K.N, Arand, M, Adamska, M, Eneyskaya, E.V, Kulminskaya, A.A, Garratt, R.C, Golubev, A.M, Polikarpov, I. Deposit date: 2004-09-01 Release date: 2004-11-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structures of beta-Galactosidase from Penicillium sp. and its Complex with Galactose J.Mol.Biol., 343, 2004
6RS9	X-ray crystal structure of LsAA9B (xylotetraose soak) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AA9, BICINE, ... Authors: Frandsen, K.E.H, Tovborg, M, Poulsen, J.C.N, Johansen, K.S, Lo Leggio, L. Deposit date: 2019-05-21 Release date: 2019-09-11 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. J.Biol.Chem., 294, 2019
8PON	TEAD2 in complex with an inhibitor Descriptor: 4-fluoranyl-2-[(3-phenylmethoxyphenyl)amino]benzoic acid, MYRISTIC ACID, Transcriptional enhancer factor TEF-4 Authors: Guichou, J.F. Deposit date: 2023-07-05 Release date: 2023-11-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg.Med.Chem.Lett., 95, 2023
8POM	TEAD2 in complex with an inhibitor Descriptor: 2-[[3-(2-phenylethoxy)phenyl]amino]pyridine-3-carboxylic acid, GLYCEROL, Transcriptional enhancer factor TEF-4 Authors: Guichou, J.F. Deposit date: 2023-07-05 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg.Med.Chem.Lett., 95, 2023
8POJ	TEAD2 in complex with an inhibitor Descriptor: 4-fluoranyl-2-[(3-phenylphenyl)amino]benzoic acid, MYRISTIC ACID, Transcriptional enhancer factor TEF-4 Authors: Guichou, J.F. Deposit date: 2023-07-05 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg.Med.Chem.Lett., 95, 2023
5O40	SOD1 bound to Ebselen Descriptor: N-phenyl-2-selanylbenzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ... Authors: Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. Deposit date: 2017-05-25 Release date: 2018-06-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9, 2018
8TH1	Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein D3L mutant Descriptor: Nucleoprotein, Ras GTPase-activating protein-binding protein 1 Authors: Hughes, M.P, Taylor, J.P, Yang, Z. Deposit date: 2023-07-13 Release date: 2023-12-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity. Cell Rep, 43, 2024
1I10	HUMAN MUSCLE L-LACTATE DEHYDROGENASE M CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETATE ION, L-LACTATE DEHYDROGENASE M CHAIN, ... Authors: Read, J.A, Winter, V.J, Eszes, C.M, Sessions, R.B, Brady, R.L. Deposit date: 2001-01-30 Release date: 2001-03-28 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase. Proteins, 43, 2001

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