9I8M
 
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6UDK
 | | HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | | Descriptor: | 1-55 Fab Heavy Chain, 1-55 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | | Authors: | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | | Deposit date: | 2019-09-19 | | Release date: | 2020-01-29 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
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9ITT
 | | Chloroflexus aurantiacus ADP-bound ATP synthase, state 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Zhang, X, Wu, J, Xu, X. | | Deposit date: | 2024-07-20 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Structure of ATP synthase from an early photosynthetic bacterium Chloroflexus aurantiacus.
Proc.Natl.Acad.Sci.USA, 122, 2025
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8FLR
 | | Human PTH1R in complex with PTHrP and Gs | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Cary, B.P, Belousoff, M.J, Piper, S.J, Wootten, D, Sexton, P.M. | | Deposit date: | 2022-12-22 | | Release date: | 2023-04-26 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Molecular insights into peptide agonist engagement with the PTH receptor.
Structure, 31, 2023
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9ITU
 | | Chloroflexus aurantiacus ADP-bound ATP synthase, state 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Zhang, X, Wu, J, Xu, X. | | Deposit date: | 2024-07-20 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Structure of ATP synthase from an early photosynthetic bacterium Chloroflexus aurantiacus.
Proc.Natl.Acad.Sci.USA, 122, 2025
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2BET
 | | Structure of Mycobacterium tuberculosis Ribose-5-Phosphate Isomerase, RpiB, Rv2465c, in complex with 4-phospho-D-erythronate. | | Descriptor: | 4-PHOSPHO-D-ERYTHRONATE, CARBOHYDRATE-PHOSPHATE ISOMERASE | | Authors: | Roos, A.K, Ericsson, D.J, Mowbray, S.L. | | Deposit date: | 2004-11-30 | | Release date: | 2004-12-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Competitive Inhibitors of Mycobacterium Tuberculosis Ribose-5-Phosphate Isomerase B Reveal New Information About the Reaction Mechanism
J.Biol.Chem., 280, 2005
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9ITS
 | | Chloroflexus aurantiacus ADP-bound ATP synthase, state 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Zhang, X, Wu, J, Xu, X. | | Deposit date: | 2024-07-20 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure of ATP synthase from an early photosynthetic bacterium Chloroflexus aurantiacus.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6X2K
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2C38
 | | RNase PH core of the archaeal exosome in complex with A5 RNA | | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ... | | Authors: | Lorentzen, E, Conti, E. | | Deposit date: | 2005-10-04 | | Release date: | 2005-11-23 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
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9I8N
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7QDK
 | | A trimeric de novo coiled-coil assembly: CC-TypeN-LaLd | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CC-TypeN-LaLd, GLYCEROL, ... | | Authors: | Kumar, P, Paterson, N.G, Woolfson, D.N. | | Deposit date: | 2021-11-27 | | Release date: | 2022-04-27 | | Last modified: | 2022-07-27 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | De novo design of discrete, stable 3 10 -helix peptide assemblies.
Nature, 607, 2022
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9HNY
 | | Mitoribosomal small subunit in complex with Mettl15 and Mettl17 | | Descriptor: | 30S ribosomal protein S8, 9S RNA, ACETYL COENZYME *A, ... | | Authors: | Zgadzay, Y, Aibara, S, Gahura, O, Amunts, A. | | Deposit date: | 2024-12-11 | | Release date: | 2025-03-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome.
Biorxiv, 2025
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9ITL
 | | Chloroflexus aurantiacus ATP synthase, state 3 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ... | | Authors: | Zhang, X, Wu, J, Xu, X. | | Deposit date: | 2024-07-20 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Structure of ATP synthase from an early photosynthetic bacterium Chloroflexus aurantiacus.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6WWC
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9ITK
 | | Chloroflexus aurantiacus ATP synthase, state 2 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ... | | Authors: | Zhang, X, Wu, J, Xu, X. | | Deposit date: | 2024-07-20 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure of ATP synthase from an early photosynthetic bacterium Chloroflexus aurantiacus.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6ZKO
 | | Native complex I, closed | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE MONOPHOSPHATE, ... | | Authors: | Kampjut, D, Sazanov, L.A. | | Deposit date: | 2020-06-30 | | Release date: | 2020-10-07 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
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6ZFB
 | | Structure of the B. subtilis RNA POLYMERASE in complex with HelD (dimer) | | Descriptor: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | | Deposit date: | 2020-06-17 | | Release date: | 2020-10-14 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling.
Nat Commun, 11, 2020
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9JVP
 | | CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, ... | | Authors: | Zhou, B, Zhao, H, Gao, Y, Chen, X, Zhang, T, He, J, Xiong, X. | | Deposit date: | 2024-10-09 | | Release date: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (2.15 Å) | | Cite: | Activation mechanism of caseinolytic chaperone-protease system in Mycobacterium tuberculosis by the anti-cancer drug bortezomib
To Be Published
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9ITJ
 | | Chloroflexus aurantiacus ATP synthase, state 1 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ... | | Authors: | Zhang, X, Wu, J, Xu, X. | | Deposit date: | 2024-07-20 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-30 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structure of ATP synthase from an early photosynthetic bacterium Chloroflexus aurantiacus.
Proc.Natl.Acad.Sci.USA, 122, 2025
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2BZI
 | | CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU2 | | Descriptor: | PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1, RU-PYRIDOCARBAZOLE-2 | | Authors: | Debreczeni, J.E, Bullock, A, Knapp, S, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A. | | Deposit date: | 2005-08-18 | | Release date: | 2005-12-08 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the Human Pim1 in Complex with Ruthenium Organometallic Ligands
To be Published
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6ZJM
 | | Atomic model of Andes virus glycoprotein spike tetramer generated by fitting into a Tula virus reconstruction | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein, ... | | Authors: | Stass, R, Huiskonen, J.T, Rey, F, Guardado-Calvo, P. | | Deposit date: | 2020-06-29 | | Release date: | 2020-10-14 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (11.4 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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6ZKK
 | | Complex I inhibited by rotenone, closed | | Descriptor: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | Authors: | Kampjut, D, Sazanov, L.A. | | Deposit date: | 2020-06-30 | | Release date: | 2020-10-07 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
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6ZLO
 | | E2 core of the fungal Pyruvate dehydrogenase complex with asymmetric interior PX30 component | | Descriptor: | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | | Authors: | Forsberg, B.O, Howard, R.J, Aibara, S, Mortesaei, N, Lindahl, E. | | Deposit date: | 2020-06-30 | | Release date: | 2020-09-23 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex.
Nat Commun, 11, 2020
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1XTN
 | | crystal structure of CISK-PX domain with sulfates | | Descriptor: | SULFATE ION, Serine/threonine-protein kinase Sgk3 | | Authors: | Xing, Y, Liu, D, Zhang, R, Joachimiak, A, Songyang, Z, Xu, W. | | Deposit date: | 2004-10-22 | | Release date: | 2004-11-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX)
J.Biol.Chem., 279, 2004
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2CLX
 | | 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects | | Descriptor: | 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, CELL DIVISION PROTEIN KINASE 2 | | Authors: | Krystof, V, Cankar, P, Frysova, I, Slouka, J, Kontopidis, G, Dzubak, P, Hajduch, M, Deazevedo, W.F, Paprskarova, M, Orsag, M, Rolcik, J, Latr, A, Fischer, P.M, Strnad, M. | | Deposit date: | 2006-05-02 | | Release date: | 2006-11-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | 4-Arylazo-3,5-Diamino-1H-Pyrazole Cdk Inhibitors: Sar Study, Crystal Structure in Complex with Cdk2, Selectivity, and Cellular Effects
J.Med.Chem., 49, 2006
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