4V7B
| Visualization of two tRNAs trapped in transit during EF-G-mediated translocation | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Ramrath, D.J.F, Lancaster, L, Sprink, T, Mielke, T, Loerke, J, Noller, H.F, Spahn, C.M.T. | Deposit date: | 2013-10-27 | Release date: | 2014-07-09 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation. Proc.Natl.Acad.Sci.USA, 110, 2013
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5SSG
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8GZC
| Crystal structure of EP300 HAT domain in complex with compound 10 | Descriptor: | (2~{R},4~{R})-4-fluoranyl-1-[1-(4-methoxyphenyl)cyclohexyl]carbonyl-~{N}-(1~{H}-pyrazolo[4,3-b]pyridin-5-yl)pyrrolidine-2-carboxamide, Histone acetyltransferase p300, ZINC ION | Authors: | Takahashi, M, Hanzawa, H. | Deposit date: | 2022-09-26 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor. J.Med.Chem., 66, 2023
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4V7Q
| Atomic model of an infectious rotavirus particle | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Core scaffold protein, ... | Authors: | Settembre, E.C, Chen, J.Z, Dormitzer, P.R, Grigorieff, N, Harrison, S.C. | Deposit date: | 2010-05-13 | Release date: | 2014-07-09 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic model of an infectious rotavirus particle. Embo J., 30, 2011
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2RJI
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8HMR
| Crystal Structure of PKM2 mutant L144P | Descriptor: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... | Authors: | Upadhyay, S, Kumar, A, Patel, A.K. | Deposit date: | 2022-12-05 | Release date: | 2023-01-11 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published
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4V5A
| Structure of the Ribosome Recycling Factor bound to the Thermus thermophilus 70S ribosome with mRNA, ASL-Phe and tRNA-fMet | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Weixlbaumer, A, Petry, S, Dunham, C.M, Selmer, M, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2007-06-28 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of the ribosome recycling factor bound to the ribosome. Nat. Struct. Mol. Biol., 14, 2007
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5SS2
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5SQD
| PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5010894382 - (R,R) and (S,S) isomers | Descriptor: | (1R,2R)-4-hydroxy-1-{[2-(hydroxymethyl)-1H-benzimidazole-5-carbonyl]amino}-2,3-dihydro-1H-indene-2-carboxylic acid, (1S,2S)-4-hydroxy-1-{[2-(hydroxymethyl)-1H-benzimidazole-5-carbonyl]amino}-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 | Authors: | Correy, G.J, Fraser, J.S. | Deposit date: | 2022-06-09 | Release date: | 2022-07-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GZ3
| Structure of human phagocyte NADPH oxidase in the resting state | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, ... | Authors: | Chen, L, Liu, R. | Deposit date: | 2022-09-24 | Release date: | 2022-12-21 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of human phagocyte NADPH oxidase in the resting state. Elife, 11, 2022
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4V7X
| Structure of the Thermus thermophilus ribosome complexed with erythromycin. | Descriptor: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. | Deposit date: | 2010-08-17 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
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5SQH
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2RFC
| Ligand bound (4-phenylimidazole) Crystal Structure of a Cytochrome P450 from the Thermoacidophilic Archaeon Picrophilus Torridus | Descriptor: | 4-PHENYL-1H-IMIDAZOLE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ho, W.W, Li, H, Poulos, T.L, Nishida, C.R, Ortiz de Montellano, P.R. | Deposit date: | 2007-09-28 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure and Properties of CYP231A2 from the Thermoacidophilic Archaeon Picrophilus torridus. Biochemistry, 47, 2008
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8H8C
| Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form | Descriptor: | C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein | Authors: | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | Deposit date: | 2022-10-22 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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8HC5
| SARS-CoV-2 wildtype S1 in complex with YB9-258 Fab and R1-32 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, Heavy chain of YB9-258 Fab, ... | Authors: | Liu, B, Gao, X, Chen, Q, Li, Z, Su, M, He, J, Xiong, X. | Deposit date: | 2022-11-01 | Release date: | 2023-01-25 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants. Nat Commun, 14, 2023
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5SQG
| PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5010894430 - (R,R) and (S,S) isomers | Descriptor: | (1R,2R)-1-{[6-(cyclopropylcarbamamido)pyridine-3-carbonyl]amino}-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid, (1S,2S)-1-{[6-(cyclopropylcarbamamido)pyridine-3-carbonyl]amino}-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid, Non-structural protein 3 | Authors: | Correy, G.J, Fraser, J.S. | Deposit date: | 2022-06-09 | Release date: | 2022-07-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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4V8V
| Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex | Descriptor: | FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE | Authors: | Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M. | Deposit date: | 2013-04-18 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex. Structure, 21, 2013
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8H8B
| Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form | Descriptor: | Putative Rhs-family protein | Authors: | Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H. | Deposit date: | 2022-10-22 | Release date: | 2023-01-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Rep, 41, 2022
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2RKF
| HIV-1 PR resistant mutant + LPV | Descriptor: | GLYCEROL, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, PROTEASE RETROPEPSIN, ... | Authors: | Rezacova, P, Brynda, J, Kozisek, M, Saskova, K.G, Konvalinka, J. | Deposit date: | 2007-10-16 | Release date: | 2008-08-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region J.Virol., 82, 2008
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5SSH
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8HDS
| Cyanophage Pam3 portal-adaptor | Descriptor: | Pam3 adaptor protein, Pam3 portal protein | Authors: | Yang, F, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2022-11-06 | Release date: | 2023-01-18 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Fine structure and assembly pattern of a minimal myophage Pam3. Proc.Natl.Acad.Sci.USA, 120, 2023
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5SS1
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2RKQ
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4W6S
| Crystal Structure of Full-Length Split GFP Mutant K126C Disulfide Dimer, P 43 21 2 Space Group | Descriptor: | GLYCEROL, PHOSPHATE ION, fluorescent protein E124H/K126C | Authors: | Leibly, D.J, Waldo, G.S, Yeates, T.O. | Deposit date: | 2014-08-20 | Release date: | 2015-02-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure, 23, 2015
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8HAO
| Human parathyroid hormone receptor-1 dimer | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha, ... | Authors: | Zhao, L, Xu, H.E, Yuan, Q. | Deposit date: | 2022-10-26 | Release date: | 2022-12-21 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1. Acta Pharmacol.Sin., 44, 2023
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