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7U0G
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structure of LIN28b nucleosome bound 3 OCT4
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-02-18
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0J
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Structure of 162bp LIN28b nucleosome
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-02-18
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0I
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Structure of LIN28b nucleosome bound 2 OCT4
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Tengfei, L, Guan, R, Bai, Y.
Deposit date:2022-02-18
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
4XZR
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Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
Descriptor: Importin subunit alpha, Inner nuclear membrane protein SRC1
Authors:Lokareddy, R.K, Cingolani, G.
Deposit date:2015-02-04
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
7T0W
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Complex of GABA-A synaptic receptor with autoimmune antibody Fab115
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab115 Heavy Chain, IgG1, ...
Authors:Noviello, C.M, Hibbs, R.E, Kreye, J, Teng, J, Pruss, H.
Deposit date:2021-11-30
Release date:2022-07-13
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanisms of GABA A receptor autoimmune encephalitis.
Cell, 185, 2022
8DIN
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BU of 8din by Molmil
The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant
Descriptor: High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, MAGNESIUM ION, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2022-06-29
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
7TPS
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Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Demonte, D.W, Maurer, M.F, Akutsu, M, Kimbung, Y.R, Logan, D.T, Walse, B.
Deposit date:2022-01-26
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.
Nat Commun, 13, 2022
8DIR
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The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant
Descriptor: High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, SODIUM ION, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2022-06-29
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
8IP2
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Escherichia coli OpgG mutant-D361N with beta-1,2-glucan
Descriptor: Glucans biosynthesis protein G, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose
Authors:Motouchi, S, Nakajima, M.
Deposit date:2023-03-13
Release date:2024-03-13
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Identification of enzymatic functions of osmo-regulated periplasmic glucan biosynthesis proteins from Escherichia coli reveals a novel glycoside hydrolase family
Commun Biol, 6, 2023
7NWF
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Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with hybrid-type glycan (GalGlcNAcMan5GlcNAc) product
Descriptor: Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Trastoy, B, Du, J.J, Garcia-Alija, M, Sundberg, E.J, Guerin, M.E.
Deposit date:2021-03-16
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:GH18 endo-beta-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans.
J.Biol.Chem., 297, 2021
7O0W
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Cryo-EM structure of the RC-dLH complex (model_1b) from Gemmatimonas phototrophica at 2.47 A
Descriptor: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
Authors:Qian, P, Koblizek, M.
Deposit date:2021-03-27
Release date:2022-03-02
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
7O0U
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Cryo-EM structure (model_1a) of the RC-dLH complex from Gemmatimonas phototrophica at 2.4 A
Descriptor: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
Authors:Qian, P, Koblizek, M.
Deposit date:2021-03-27
Release date:2022-03-02
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
7O0X
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Cryo-EM structure (model_2b) of the RC-dLH complex from Gemmatimonas phototrophica at 2.44 A
Descriptor: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
Authors:Qian, P, Koblizek, M.
Deposit date:2021-03-28
Release date:2022-03-02
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
7O0V
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Cryo-EM structure (model_2a) of the RC-dLH complex from Gemmatimonas phototrophica at 2.5 A
Descriptor: (19R,22S)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9Z)-hexadec-9-enoate, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, ...
Authors:Qian, P, Koblizek, M.
Deposit date:2021-03-27
Release date:2022-03-02
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:2.4- angstrom structure of the double-ring Gemmatimonas phototrophica photosystem.
Sci Adv, 8, 2022
8BY3
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BU of 8by3 by Molmil
FimH lectin domain in complex with oligomannose-6
Descriptor: NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ...
Authors:Bouckaert, J, Bourenkov, G.P.
Deposit date:2022-12-11
Release date:2023-04-12
Last modified:2023-04-26
Method:X-RAY DIFFRACTION (3.186 Å)
Cite:Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors.
J.Biol.Chem., 299, 2023
7T0Z
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Complex of GABA-A synaptic receptor with autoimmune antibody Fab175
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab175 IgG1 heavy chain, ...
Authors:Noviello, C.M, Hibbs, R.E, Kreye, J, Teng, J, Pruss, H.
Deposit date:2021-11-30
Release date:2022-07-13
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanisms of GABA A receptor autoimmune encephalitis.
Cell, 185, 2022
7T2P
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The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-06
Release date:2022-10-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
7T4G
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The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-09
Release date:2022-10-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
8JBA
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BU of 8jba by Molmil
Discovery and Crystallography Study of Novel Oxadiazole Analogs as Small Molecule PD-1/PD-L1 inhibitors
Descriptor: (2~{S})-2-[[3-[[5-[(2-methyl-3-phenyl-phenoxy)methyl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]methylamino]-3-oxidanyl-propanoic acid, Programmed cell death 1 ligand 1
Authors:Cheng, Y, Xiao, Y.B.
Deposit date:2023-05-08
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery and Crystallography Study of Novel Biphenyl Ether and Oxadiazole Thioether (Non-Arylmethylamine)-Based Small-Molecule PD-1/PD-L1 Inhibitors as Immunotherapeutic Agents.
J.Med.Chem., 66, 2023
8J6Z
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BU of 8j6z by Molmil
Cryo-EM structure of the Arabidopsis thaliana photosystem I(PSI-LHCII-ST2)
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Chen, S.J.B, Wu, J.H, Sui, S.F, Zhang, L.X.
Deposit date:2023-04-26
Release date:2023-11-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Regulatory dynamics of the higher-plant PSI-LHCI supercomplex during state transitions.
Mol Plant, 16, 2023
8J7A
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BU of 8j7a by Molmil
Coordinates of Cryo-EM structure of the Arabidopsis thaliana PSI in state 1 (PSI-ST1)
Descriptor: (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
Authors:Chen, S.J.B, Wu, J.H, Sui, S.F, Zhang, L.X.
Deposit date:2023-04-27
Release date:2023-11-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Regulatory dynamics of the higher-plant PSI-LHCI supercomplex during state transitions.
Mol Plant, 16, 2023
8J7B
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BU of 8j7b by Molmil
Coordinates of Cryo-EM structure of the Arabidopsis thaliana PSI in state 2 (PSI-ST2)
Descriptor: (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
Authors:Chen, S.J.B, Wu, J.H, Sui, S.F, Zhang, L.X.
Deposit date:2023-04-27
Release date:2023-11-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Regulatory dynamics of the higher-plant PSI-LHCI supercomplex during state transitions.
Mol Plant, 16, 2023
4YEE
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beta2 carbohydrate binding module (CBM) of AMP-activated protein kinase (AMPK) in complex with glucosyl-beta-cyclodextrin
Descriptor: 5'-AMP-activated protein kinase subunit beta-2, Cyclic alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-[alpha-D-glucopyranose-(1-6)]alpha-D-glucopyranose, GLYCEROL
Authors:Mobbs, J, Gorman, M.A, Parker, M.W, Gooley, P.R, Griffin, M.
Deposit date:2015-02-24
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Biochem.J., 468, 2015
4YMI
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BU of 4ymi by Molmil
Crystal structure of probable nicotinate-nucleotide adenylyltransferase from Mycobacterium abcessus in complex with NADP
Descriptor: ADENINE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable nicotinate-nucleotide adenylyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-03-06
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of probable nicotinate-nucleotide adenylyltransferase from Mycobacterium abcessus in complex with NADP
to be published
7RGF
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Protocadherin gammaC4 EC1-4 crystal structure disrupted trans interface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L.
Deposit date:2021-07-15
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.
Elife, 11, 2022

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