1E2Y
 
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4EO3
 | | Peroxiredoxin Nitroreductase Fusion Enzyme | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, Bacterioferritin comigratory protein/NADH dehydrogenase, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Prosper, P, Haouz, A, Navaza, A, Jacquot, J.-P, Rouhier, N. | | Deposit date: | 2012-04-13 | | Release date: | 2012-10-17 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.649 Å) | | Cite: | In the absence of thioredoxins, what are the reductants for peroxiredoxins in Thermotoga maritima?
Antioxid Redox Signal, 18, 2013
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5JCG
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5XBR
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5XBQ
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6P0W
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5JLY
 | | Structure of Peroxiredoxin-1 from Schistosoma japonicum | | Descriptor: | Thioredoxin peroxidase-1 | | Authors: | Wu, Q, Huang, F, Zeng, D, Liu, X, Zhao, J, Wang, H, Peng, Y, Li, P, Li, Y. | | Deposit date: | 2016-04-27 | | Release date: | 2017-05-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.051 Å) | | Cite: | Crystal structure of Peroxiredoxin-1 from Schistosoma japonicum
To Be Published
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6E0G
 | | Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein | | Descriptor: | mitochondrial 2-cys-peroxiredoxin | | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | | Deposit date: | 2018-07-06 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
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6E0F
 | | Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress | | Descriptor: | mitochondrial 2-cys-peroxiredoxin | | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | | Deposit date: | 2018-07-06 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
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6Q5V
 | | 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus | | Descriptor: | Peroxiredoxin | | Authors: | Stroobants, S, Maes, D, Peeters, E, van Molle, I. | | Deposit date: | 2018-12-09 | | Release date: | 2019-05-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.747 Å) | | Cite: | Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus.
Acta Crystallogr.,Sect.F, 75, 2019
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7WEU
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7WET
 | | Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela | | Descriptor: | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1 | | Authors: | Zhang, H, Luo, C. | | Deposit date: | 2021-12-24 | | Release date: | 2022-12-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
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8HH0
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8HLA
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8EKW
 | | Cryo-EM structure of human PRDX4 | | Descriptor: | Peroxiredoxin-4 | | Authors: | Su, C.C. | | Deposit date: | 2022-09-22 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
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3TJG
 | | Crystal Structure of human peroxiredoxin IV C51A mutant in oxidized form | | Descriptor: | Peroxiredoxin-4 | | Authors: | Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. | | Deposit date: | 2011-08-24 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle.
J.Biol.Chem., 286, 2011
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6KRR
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3TKS
 | | Crystal structure of full-length human peroxiredoxin 4 in three different redox states | | Descriptor: | PEROXIDE ION, Peroxiredoxin-4 | | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | Deposit date: | 2011-08-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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6KRM
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3TKP
 | | Crystal structure of full-length human peroxiredoxin 4 in the reduced form | | Descriptor: | Peroxiredoxin-4 | | Authors: | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | Deposit date: | 2011-08-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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6KRS
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5UKA
 | | Salmonella typhimurium AhpC E49Q mutant | | Descriptor: | Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, POTASSIUM ION, ... | | Authors: | Perkins, A, Nelson, K, Parsonage, D, Poole, L, Karplus, P.A. | | Deposit date: | 2017-01-20 | | Release date: | 2018-01-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
Antioxid.Redox Signal., 28, 2018
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2NVL
 | | Crystal structure of archaeal peroxiredoxin, thioredoxin peroxidase from Aeropyrum pernix K1 (sulfonic acid form) | | Descriptor: | Probable peroxiredoxin | | Authors: | Nakamura, T, Yamamoto, T, Abe, M, Matsumura, H, Hagihara, Y, Goto, T, Yamaguchi, T, Inoue, T. | | Deposit date: | 2006-11-13 | | Release date: | 2007-11-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5UCX
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2PN8
 | | Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase) | | Descriptor: | Peroxiredoxin-4 | | Authors: | Pilka, E.S, Kavanagh, K.L, Cooper, C, von Delft, F, Sundstrom, M, Arrowsmith, C.A, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-04-24 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase).
To be Published
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