3QUL
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![BU of 3qul by Molmil](/molmil-images/mine/3qul) | Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 altered peptide ligand (Y4S) | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Allerbring, E, Duru, A.D, Uchtenhagen, H, Madhurantakam, C, Grimm, S, Tomek, M.B, Mazumdar, P.A, Spetz, A, Friemann, R, Sandalova, T, Uhlin, M, Nygren, P, Achour, A. | Deposit date: | 2011-02-24 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics. Eur.J.Immunol., 42, 2012
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2BVQ
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![BU of 2bvq by Molmil](/molmil-images/mine/2bvq) | Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression | Descriptor: | BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y. | Deposit date: | 2005-07-01 | Release date: | 2005-09-07 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression. J Immunol., 175, 2005
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2NY2
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![BU of 2ny2 by Molmil](/molmil-images/mine/2ny2) | HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ... | Authors: | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | Deposit date: | 2006-11-20 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
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5VVP
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![BU of 5vvp by Molmil](/molmil-images/mine/5vvp) | HLA-B*57:03 presenting LSSPVTKSW | Descriptor: | Beta-2-microglobulin, LEU-SER-SER-PRO-VAL-THR-LYS-SER-TRP, MHC class I antigen | Authors: | Pymm, P, Rossjohn, J, Vivian, J.P. | Deposit date: | 2017-05-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
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2NY3
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![BU of 2ny3 by Molmil](/molmil-images/mine/2ny3) | HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | Authors: | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | Deposit date: | 2006-11-20 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
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3P9L
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![BU of 3p9l by Molmil](/molmil-images/mine/3p9l) | Crystal Structure of H2-Kb in complex with the chicken ovalbumin epitope OVA | Descriptor: | Beta-2-microglobulin, CALCIUM ION, H-2 class I histocompatibility antigen, ... | Authors: | Wesselingh, R, Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J. | Deposit date: | 2010-10-18 | Release date: | 2011-10-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses J.Immunol., 187, 2011
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8ECQ
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![BU of 8ecq by Molmil](/molmil-images/mine/8ecq) | Bovine Fab 2G3 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2022-09-02 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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2NXY
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![BU of 2nxy by Molmil](/molmil-images/mine/2nxy) | HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ... | Authors: | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | Deposit date: | 2006-11-20 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
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4NQX
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![BU of 4nqx by Molmil](/molmil-images/mine/4nqx) | |
3LKN
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![BU of 3lkn by Molmil](/molmil-images/mine/3lkn) | Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | Authors: | Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. | Deposit date: | 2010-01-27 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses. Proc.Natl.Acad.Sci.USA, 107, 2010
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5WSH
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![BU of 5wsh by Molmil](/molmil-images/mine/5wsh) | Structure of HLA-A2 P130 | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ... | Authors: | Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S. | Deposit date: | 2016-12-07 | Release date: | 2017-12-20 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress. J. Virol., 92, 2018
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7FAB
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![BU of 7fab by Molmil](/molmil-images/mine/7fab) | |
2Q76
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![BU of 2q76 by Molmil](/molmil-images/mine/2q76) | Mouse anti-hen egg white lysozyme antibody F10.6.6 Fab fragment | Descriptor: | Fab F10.6.6 fragment Heavy Chain, Fab F10.6.6 fragment Light Chain | Authors: | Cauerhff, A, Klinke, S, Acierno, J.P, Goldbaum, F.A, Braden, B.C. | Deposit date: | 2007-06-06 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies. J.Mol.Biol., 374, 2007
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3V5D
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![BU of 3v5d by Molmil](/molmil-images/mine/3v5d) | HLA-A2.1 KVAELVHFL | Descriptor: | Beta-2-microglobulin, HIV peptide KVAELVHFL, HLA class I histocompatibility antigen, ... | Authors: | Collins, E.J, Lee, H.Y. | Deposit date: | 2011-12-16 | Release date: | 2012-12-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Prediction of conformation and immunogenicity of peptides bound to MHC molecules To be Published
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2CLR
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![BU of 2clr by Molmil](/molmil-images/mine/2clr) | |
5KSA
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![BU of 5ksa by Molmil](/molmil-images/mine/5ksa) | Bel602-DQ8.5-glia-gamma1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel602 alpha TRAV20*01, Bel602 beta TRBV9*01, ... | Authors: | Petersen, J, Rossjohn, J, Reid, H.H. | Deposit date: | 2016-07-08 | Release date: | 2016-09-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution. Structure, 24, 2016
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4NO2
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![BU of 4no2 by Molmil](/molmil-images/mine/4no2) | Crystal structure of RQA_V phosphopeptide bound to HLA-A2 | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Mohammed, F, Stones, D.H, Willcox, B.E. | Deposit date: | 2013-11-19 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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6E9H
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![BU of 6e9h by Molmil](/molmil-images/mine/6e9h) | |
5VUD
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![BU of 5vud by Molmil](/molmil-images/mine/5vud) | HLA-B*57:01 presenting LSSPVTKSW | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | Authors: | Pymm, P, Rossjohn, J, Vivian, J.P. | Deposit date: | 2017-05-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
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6CW9
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![BU of 6cw9 by Molmil](/molmil-images/mine/6cw9) | Structure of alpha-GC[8,16P] bound by CD1d and in complex with the Va14Vb8.2 TCR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, J, Zajonc, D. | Deposit date: | 2018-03-30 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides. J.Biol.Chem., 294, 2019
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1T0M
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![BU of 1t0m by Molmil](/molmil-images/mine/1t0m) | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | Descriptor: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | Authors: | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | Deposit date: | 2004-04-12 | Release date: | 2004-11-23 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173, 2004
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25C8
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![BU of 25c8 by Molmil](/molmil-images/mine/25c8) | CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX | Descriptor: | IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION | Authors: | Gruber, K, Wilson, I.A. | Deposit date: | 1998-03-18 | Release date: | 1999-03-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for antibody catalysis of a disfavored ring closure reaction. Biochemistry, 38, 1999
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2R2H
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![BU of 2r2h by Molmil](/molmil-images/mine/2r2h) | Structure of S25-2 in Complex with Ko | Descriptor: | Fab, antibody fragment (IgG1k), heavy chain, ... | Authors: | Brooks, C.L, Evans, S.V. | Deposit date: | 2007-08-25 | Release date: | 2008-12-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
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5T6Z
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![BU of 5t6z by Molmil](/molmil-images/mine/5t6z) | KIR3DL1 in complex with HLA-B*57:01-TW10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-THR-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ... | Authors: | Pymm, P, Rossjohn, J, Vivian, J.P. | Deposit date: | 2016-09-02 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nat. Struct. Mol. Biol., 24, 2017
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1LO2
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![BU of 1lo2 by Molmil](/molmil-images/mine/1lo2) | Retro-Diels-Alderase Catalytic Antibody | Descriptor: | If kappa light chain, Ig gamma 2a heavy chain, [2'-CARBOXYLETHYL]-10-METHYL-ANTHRACENE ENDOPEROXIDE | Authors: | Hugot, M, Reymond, J.L, Baumann, U. | Deposit date: | 2002-05-06 | Release date: | 2002-06-26 | Last modified: | 2021-07-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue. Proc.Natl.Acad.Sci.USA, 99, 2002
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