2Q76

Mouse anti-hen egg white lysozyme antibody F10.6.6 Fab fragment

Summary for 2Q76

• Entry DOI: 10.2210/pdb2q76/pdb
• Related: 1MLB 1MLC 1P2C
• Descriptor: Fab F10.6.6 fragment Light Chain, Fab F10.6.6 fragment Heavy Chain (3 entities in total)
• Functional Keywords: antibody, fab fragment, lysozyme, affinity maturation, vh-vl interface., immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 93038.87

Authors

Cauerhff, A.,Klinke, S.,Acierno, J.P.,Goldbaum, F.A.,Braden, B.C. (deposition date: 2007-06-06, release date: 2008-03-18, Last modification date: 2023-08-30)

• Primary citation: Acierno, J.P.,Braden, B.C.,Klinke, S.,Goldbaum, F.A.,Cauerhff, A.; Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies.; J.Mol.Biol., 374:130-146, 2007; PubMed: 17916365; DOI: 10.1016/j.jmb.2007.09.005

Experimental method

X-RAY DIFFRACTION (2 Å)