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5HYF
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Glycosylated Knob-Knob Fc fragment (P6122)
Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kuglstatter, A, Stihle, M, Benz, J.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products.
Protein Eng. Des. Sel., 30, 2017
3LSF
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BU of 3lsf by Molmil
Piracetam bound to the ligand binding domain of GluA2
Descriptor: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ...
Authors:Ahmed, A.H, Ptak, C.P, Oswald, R.E.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
6XJB
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IgA1 Protease
Descriptor: Immunoglobulin A1 protease
Authors:Eisenmesser, E.Z, Zheng, H.
Deposit date:2020-06-23
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease.
Nat Commun, 11, 2020
5HYE
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BU of 5hye by Molmil
Glycosylated Knob-Knob Fc fragment (P212121)
Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kuglstatter, A, Stihle, M, Benz, J.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products.
Protein Eng. Des. Sel., 30, 2017
6XTY
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CryoEM structure of human CMG bound to AND-1 (CMGA)
Descriptor: Cell division control protein 45 homolog, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Rzechorzek, N.J, Pellegrini, L, Chirgadze, D.Y, Hardwick, S.W.
Deposit date:2020-01-16
Release date:2020-05-27
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (6.77 Å)
Cite:CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
Nucleic Acids Res., 48, 2020
5HZV
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BU of 5hzv by Molmil
Crystal structure of the zona pellucida module of human endoglin/CD105
Descriptor: GLYCEROL, Maltose-binding periplasmic protein,Endoglin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Bokhove, M, Saito, T, Jovine, L.
Deposit date:2016-02-03
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
5HY9
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BU of 5hy9 by Molmil
Glycosylated, disulfide-linked Knob-into-Hole Fc fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kuglstatter, A, Stihle, M, Benz, J.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products.
Protein Eng. Des. Sel., 30, 2017
6XWW
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BU of 6xww by Molmil
Constitutive decay element CDE1 from human 3'UTR
Descriptor: CDE1
Authors:Schwalbe, H, Binas, O.
Deposit date:2020-01-24
Release date:2020-05-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the recognition of transiently structured AU-rich elements by Roquin.
Nucleic Acids Res., 48, 2020
6XW6
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BU of 6xw6 by Molmil
Crystal structure of murine norovirus P domain in complex with Nanobody NB-5853
Descriptor: 1,2-ETHANEDIOL, Capsid protein, MAGNESIUM ION, ...
Authors:Kilic, T, Sabin, C, Hansman, G.
Deposit date:2020-01-23
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Nanobody-Mediated Neutralization Reveals an Achilles Heel for Norovirus.
J.Virol., 94, 2020
3LSL
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BU of 3lsl by Molmil
Piracetam bound to the ligand binding domain of GluA2 (flop form)
Descriptor: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ...
Authors:Ahmed, A.H, Oswald, R.E.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.122 Å)
Cite:Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
5HQP
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BU of 5hqp by Molmil
Crystal structure of the ERp44-peroxiredoxin 4 complex
Descriptor: Endoplasmic reticulum resident protein 44, Peroxiredoxin-4
Authors:Yang, K, Li, D.F, Wang, X, Wang, C.C.
Deposit date:2016-01-22
Release date:2016-10-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention.
Structure, 24, 2016
6XX0
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BU of 6xx0 by Molmil
Crystal structure of NEMO in complex with Ubv-LIN
Descriptor: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b, ...
Authors:Akutsu, M, Skenderovic, A, Garcia-Pardo, J, Maculins, T, Dikic, I.
Deposit date:2020-01-26
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell Chem Biol, 27, 2020
6XW4
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BU of 6xw4 by Molmil
Crystal structure of murine norovirus P domain in complex with Nanobody NB-5867
Descriptor: 1,2-ETHANEDIOL, Capsid protein, Nanobody NB-5867
Authors:Kilic, T, Sabin, C, Hansman, G.
Deposit date:2020-01-23
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Nanobody-Mediated Neutralization Reveals an Achilles Heel for Norovirus.
J.Virol., 94, 2020
5HYC
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BU of 5hyc by Molmil
Structure based function annotation of a hypothetical protein MGG_01005 related to the development of rice blast fungus
Descriptor: Cytoplasmic dynein 1 intermediate chain 2, Uncharacterized protein
Authors:Liu, J, Li, G, Huang, J, Peng, Y.-l.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3.
Sci Rep, 8, 2018
7ZFW
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BU of 7zfw by Molmil
Structure of human 80S ribosome obtained from ssDNA coated grid
Descriptor: RNA (615-MER)
Authors:Hrebik, D, Plevka, P.
Deposit date:2022-04-01
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules.
Acta Crystallogr D Struct Biol, 78, 2022
6S1R
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BU of 6s1r by Molmil
Structure of fission yeast Mis16 bound to histone H4
Descriptor: Histone H4, Histone acetyltransferase type B subunit 2
Authors:Lefevre, S, Korntner-Vetter, M, Singleton, M.R.
Deposit date:2019-06-19
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Subunit interactions and arrangements in the fission yeast Mis16-Mis18-Mis19 complex.
Life Sci Alliance, 2, 2019
7YQK
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BU of 7yqk by Molmil
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1
Descriptor: DNA (145-MER), Histone H2AX, Histone H2B, ...
Authors:Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L.
Deposit date:2022-08-07
Release date:2022-08-17
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.
J.Am.Chem.Soc., 144, 2022
7ZE1
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BU of 7ze1 by Molmil
Tribolium castaneum hexamerin 2
Descriptor: Larval serum protein 1 gamma chain-like Protein
Authors:Valentova, L, Fuzik, T, Plevka, P.
Deposit date:2022-03-30
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules.
Acta Crystallogr D Struct Biol, 78, 2022
6XJ7
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BU of 6xj7 by Molmil
Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni
Descriptor: Pgp2
Authors:Lin, C.S, Chan, A.C, Murphy, M.E.
Deposit date:2020-06-23
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.
J.Biol.Chem., 296, 2021
6XJ6
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BU of 6xj6 by Molmil
Crystal structure of the helical cell shape determining protein Pgp2 from Campylobacter jejuni
Descriptor: Pgp2
Authors:Lin, C.S, Chan, A.C, Murphy, M.E.
Deposit date:2020-06-23
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.
J.Biol.Chem., 296, 2021
7ZG7
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BU of 7zg7 by Molmil
Structure of human Apoferritin obtained from ssDNA coated grid
Descriptor: Ferritin heavy chain, SODIUM ION, ZINC ION
Authors:Hrebik, D, Plevka, P.
Deposit date:2022-04-02
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (1.77 Å)
Cite:Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules.
Acta Crystallogr D Struct Biol, 78, 2022
7CMJ
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BU of 7cmj by Molmil
Crystal structure of L.donovani Hypoxanthine-guanine phosphoribosyl transferase (HGPRT)
Descriptor: BARIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Parihar, P.S, Pratap, J.V.
Deposit date:2020-07-27
Release date:2021-08-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The L.donovani Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) oligomer is distinct from the human homolog.
Biochem.Biophys.Res.Commun., 532, 2020
6M17
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BU of 6m17 by Molmil
The 2019-nCoV RBD/ACE2-B0AT1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Guo, Y.Y, Zhou, Q.
Deposit date:2020-02-24
Release date:2020-03-11
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.
Science, 367, 2020
5I05
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BU of 5i05 by Molmil
Crystal structure of human BMP9 at 1.87 A resolution
Descriptor: GLYCEROL, Growth/differentiation factor 2
Authors:Saito, T, Bokhove, M, Jovine, L.
Deposit date:2016-02-03
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
7YNY
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BU of 7yny by Molmil
Crystal structure of baculovirus LEF-3 from Helicoverpa armigera nucleopolyhedrovirus
Descriptor: Lef3
Authors:Yin, J, Li, Z, Cao, S.
Deposit date:2022-08-01
Release date:2023-01-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Structural transitions during the cooperative assembly of baculovirus single-stranded DNA-binding protein on ssDNA.
Nucleic Acids Res., 50, 2022

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