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6B7M
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BU of 6b7m by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) in complex with Ubiquitin
Descriptor: Polyubiquitin-C, SdeD (lpg2509)
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6B7O
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BU of 6b7o by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin
Descriptor: Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6EML
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BU of 6eml by Molmil
Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae
Descriptor: 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ...
Authors:Heuer, A, Thomson, E, Schmidt, C, Berninghausen, O, Becker, T, Hurt, E, Beckmann, R.
Deposit date:2017-10-02
Release date:2017-11-29
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of a late pre-40S ribosomal subunit fromSaccharomyces cerevisiae.
Elife, 6, 2017
6EI1
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BU of 6ei1 by Molmil
Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA
Descriptor: GLYCEROL, MALONATE ION, Polyubiquitin-B, ...
Authors:Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T.
Deposit date:2017-09-16
Release date:2018-03-07
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.732 Å)
Cite:A family of unconventional deubiquitinases with modular chain specificity determinants.
Nat Commun, 9, 2018
5YDR
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BU of 5ydr by Molmil
Structure of DNMT1 RFTS domain in complex with ubiquitin
Descriptor: DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ...
Authors:Qian, C.
Deposit date:2017-09-14
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.
Nucleic Acids Res., 46, 2018
5YDK
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BU of 5ydk by Molmil
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, tetrameric form
Descriptor: E3 ubiquitin-protein ligase RNF168, GLYCEROL, Ubiquitin-40S ribosomal protein S27a
Authors:Takahashi, T.S, Sato, Y, Fukai, S.
Deposit date:2017-09-13
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.505 Å)
Cite:Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168
Nat Commun, 9, 2018
6AZ1
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BU of 6az1 by Molmil
Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin
Descriptor: E-site tRNA, LACK1, MAGNESIUM ION, ...
Authors:Shalev-Benami, M, Zhang, Y, Rozenberg, H, Matzov, D, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
5YCA
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BU of 5yca by Molmil
Crystal structure of inner membrane protein Bqt4 in complex with LEM2
Descriptor: Lap-Emerin-Man domain protein 2, Ubiquitin-like protein SMT3,Bouquet formation protein 4
Authors:Chen, Y, Hu, C.
Deposit date:2017-09-07
Release date:2018-11-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast.
Nucleic Acids Res., 47, 2019
5OXH
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BU of 5oxh by Molmil
C-terminally retracted ubiquitin T66V/L67N mutant
Descriptor: SULFATE ION, Ubiquitin T66V/L67N mutant
Authors:Gladkova, C, Schubert, A.F, Wagstaff, J.L, Pruneda, J.P, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
5YC2
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BU of 5yc2 by Molmil
Crystal structure of inner membrane protein Bqt4 in complex with telomeric protein Rap1
Descriptor: DNA-binding protein rap1, Ubiquitin-like protein SMT3,Bouquet formation protein 4
Authors:Chen, Y, Hu, C.
Deposit date:2017-09-06
Release date:2018-11-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast.
Nucleic Acids Res., 47, 2019
5OXI
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BU of 5oxi by Molmil
C-terminally retracted ubiquitin L67S mutant
Descriptor: SULFATE ION, Ubiquitin L67S mutant
Authors:Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
6ASR
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BU of 6asr by Molmil
REV1 UBM2 domain complex with ubiquitin
Descriptor: DNA repair protein REV1, NICKEL (II) ION, Ubiquitin
Authors:Miller, D.J.
Deposit date:2017-08-25
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.356 Å)
Cite:Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction.
J. Mol. Biol., 430, 2018
6AQR
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BU of 6aqr by Molmil
SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin
Descriptor: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ...
Authors:Morrow, M.E, Morgan, M.T, Wolberger, C.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins.
EMBO Rep., 19, 2018
5OPT
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BU of 5opt by Molmil
Structure of KSRP in context of Trypanosoma cruzi 40S
Descriptor: 18S rRNA, 40S ribosomal protein S10, putative, ...
Authors:Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y.
Deposit date:2017-08-10
Release date:2017-11-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017
5OHV
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BU of 5ohv by Molmil
K33-specific affimer bound to K33 diUb
Descriptor: GLYCEROL, K33-specific affimer, SULFATE ION, ...
Authors:Michel, M.A, Komander, D.
Deposit date:2017-07-18
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Mol. Cell, 68, 2017
5OHN
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BU of 5ohn by Molmil
Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (low resolution)
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION
Authors:Gersch, M, Komander, D.
Deposit date:2017-07-17
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
5OHP
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BU of 5ohp by Molmil
Crystal structure of USP30 (C77A) in complex with Lys6-linked diubiquitin
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION
Authors:Gersch, M, Komander, D.
Deposit date:2017-07-17
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
5OHK
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BU of 5ohk by Molmil
Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (high resolution)
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ...
Authors:Gersch, M, Komander, D.
Deposit date:2017-07-17
Release date:2017-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
5OHL
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BU of 5ohl by Molmil
K6-specific affimer bound to K6 diUb
Descriptor: GLYCEROL, K6-specific affimer, POLYETHYLENE GLYCOL (N=34), ...
Authors:Michel, M.A, Komander, D.
Deposit date:2017-07-17
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Mol. Cell, 68, 2017
5OHM
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BU of 5ohm by Molmil
K33-specific affimer bound to K33 diUb
Descriptor: K33-specific affimer, POLYETHYLENE GLYCOL (N=34), Polyubiquitin-C
Authors:Michel, M.A, Komander, D.
Deposit date:2017-07-17
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Mol. Cell, 68, 2017
5WFI
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BU of 5wfi by Molmil
X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
Descriptor: FORMIC ACID, GLYCEROL, Ubiquitin, ...
Authors:Mesecar, A.D, Chen, Y.
Deposit date:2017-07-12
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
To Be Published
5OE7
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BU of 5oe7 by Molmil
Structure of OTULIN bound to the Met1-linked diubiquitin activity probe
Descriptor: Polyubiquitin-C, Ubiquitin thioesterase otulin
Authors:Elliott, P.R, Komander, D.
Deposit date:2017-07-07
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017
5XY3
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BU of 5xy3 by Molmil
Large subunit of Trichomonas vaginalis ribosome
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
Deposit date:2017-07-06
Release date:2017-08-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
5XXU
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BU of 5xxu by Molmil
Small subunit of Toxoplasma gondii ribosome
Descriptor: 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ...
Authors:LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
Deposit date:2017-07-05
Release date:2017-08-30
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
5XVE
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BU of 5xve by Molmil
Crystal structure of human USP2 C276S mutant in complex with ubiquitin
Descriptor: Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin-40S ribosomal protein S27a, ZINC ION
Authors:Chou, C.Y, Tang, H.C.
Deposit date:2017-06-27
Release date:2018-02-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2
Sci Rep, 8, 2018

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