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6O65	Crystal Structure of Arabidopsis thaliana Spermidine Synthase isoform 1 (AtSPDS1) in complex with decarboxylated S-adenosylmethionine and cyclohexylamine Descriptor: 1,2-ETHANEDIOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, CYCLOHEXYLAMMONIUM ION, ... Authors: Sekula, B, Dauter, Z. Deposit date: 2019-03-05 Release date: 2019-06-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Spermidine Synthase (SPDS) Undergoes Concerted Structural Rearrangements Upon Ligand Binding - A Case Study of the Two SPDS Isoforms FromArabidopsis thaliana. Front Plant Sci, 10, 2019
8TYS	Adaptive mechanism of collagen IV scaffold assembly in Drosophila: crystal structure of tissue-extracted NC1 hexamer Descriptor: CALCIUM ION, CHLORIDE ION, Collagen IV, ... Authors: Boudko, S.P. Deposit date: 2023-08-25 Release date: 2023-11-08 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Collagen IV of basement membranes: IV. Adaptive mechanism of collagen IV scaffold assembly in Drosophila. J.Biol.Chem., 299, 2023
8TXN	Adaptive mechanism of collagen IV scaffold assembly in Drosophila: crystal structure of recombinant NC1 hexamer Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Collagen alpha-1(IV) chain, ... Authors: Boudko, S.P. Deposit date: 2023-08-23 Release date: 2023-11-08 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Collagen IV of basement membranes: IV. Adaptive mechanism of collagen IV scaffold assembly in Drosophila. J.Biol.Chem., 299, 2023
7BUT	N-terminal domain (NTD) Solution structure of aciniform spidroin (AcSpN) from Nephila antipodiana. Descriptor: Aciniform Spidroin Authors: Fan, J.S, Yang, D.W. Deposit date: 2020-04-08 Release date: 2020-07-22 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural Basis of Oligomerization of N-Terminal Domain of Spider Aciniform Silk Protein. Int J Mol Sci, 21, 2020
3MZG	Crystal structure of a human prolactin receptor antagonist in complex with the extracellular domain of the human prolactin receptor Descriptor: CHLORIDE ION, Prolactin, Prolactin receptor, ... Authors: Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. Deposit date: 2010-05-12 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
7CA3	Cryo-EM structure of human GABA(B) receptor bound to the positive allosteric modulator rac-BHFF Descriptor: (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... Authors: Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. Deposit date: 2020-06-08 Release date: 2020-11-11 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
7CLA	Crystal structure of HTH-type transcriptional regulator SkgA from Caulobacter crescentus Descriptor: HTH-type transcriptional regulator SkgA Authors: Jiang, X, Zhang, L, Teng, M, Li, X. Deposit date: 2020-07-20 Release date: 2020-10-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Antibiotic binding releases autoinhibition of the TipA multidrug-resistance transcriptional regulator. J.Biol.Chem., 295, 2020
6OKS	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
3N06	A mutant human Prolactin receptor antagonist H27A in complex with the extracellular domain of the human prolactin receptor Descriptor: CHLORIDE ION, Prolactin, Prolactin receptor, ... Authors: Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. Deposit date: 2010-05-13 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
7PVI	dTDP-sugar epimerase Descriptor: CITRATE ANION, SODIUM ION, alpha-D-xylopyranose, ... Authors: Cross, A.R, Harmer, N.J, Isupov, M.N. Deposit date: 2021-10-04 Release date: 2022-04-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.434 Å) Cite: Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
7PWB	dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ... Authors: Cross, A.R, Harmer, N.J, Isupov, M.N. Deposit date: 2021-10-06 Release date: 2022-04-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
7PWH	Structure of the dTDP-sugar epimerase StrM Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ... Authors: Cross, A.R, Harmer, N.J, Isupov, M.N. Deposit date: 2021-10-06 Release date: 2022-04-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
7PWI	Structure of the dTDP-sugar epimerase StrM Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase Authors: Cross, A.R, Harmer, N.J, Isupov, M.N. Deposit date: 2021-10-06 Release date: 2022-04-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.326 Å) Cite: Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases. J.Biol.Chem., 298, 2022
8U1R	Prefusion-stabilized Langya virus F protein, variant G99C/I109C Descriptor: Fusion glycoprotein F Authors: Byrne, P.O, McLellan, J.S. Deposit date: 2023-09-01 Release date: 2023-12-27 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Prefusion stabilization of the Hendra and Langya virus F proteins. J.Virol., 98, 2024
7CAF	Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state Descriptor: ABC sugar transporter, permease component, ABC transporter, ... Authors: Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. Deposit date: 2020-06-08 Release date: 2020-12-02 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
6O63	Crystal Structure of Arabidopsis thaliana Spermidine Synthase isoform 1 (AtSPDS1) Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... Authors: Sekula, B, Dauter, Z. Deposit date: 2019-03-05 Release date: 2019-06-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Spermidine Synthase (SPDS) Undergoes Concerted Structural Rearrangements Upon Ligand Binding - A Case Study of the Two SPDS Isoforms FromArabidopsis thaliana. Front Plant Sci, 10, 2019
7CM5	Full-length Sarm1 in a self-inhibited state Descriptor: NAD(+) hydrolase SARM1 Authors: Zhang, Z, Jiang, Y. Deposit date: 2020-07-24 Release date: 2020-10-21 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588, 2020
3N0P	A mutant human Prolactin receptor antagonist H30A in complex with the extracellular domain of the human prolactin receptor Descriptor: CHLORIDE ION, Prolactin, Prolactin receptor, ... Authors: Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. Deposit date: 2010-05-14 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
7CFL	X-ray structure of autolysin Acd24020 catalytic domain from Clostridium difficile Descriptor: CITRATE ANION, Putative cell wall hydrolase phosphatase-associated protein Authors: Kamitori, S, Tamai, E. Deposit date: 2020-06-26 Release date: 2020-11-25 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Structural and biochemical characterizations of the novel autolysin Acd24020 from Clostridioides difficile and its full-function catalytic domain as a lytic enzyme. Mol.Microbiol., 115, 2021
6OAS	Structure of canine parvovirus in complex with transferrin receptor type-1 Descriptor: Capsid protein VP1 Authors: Lee, H, Hafenstein, S. Deposit date: 2019-03-18 Release date: 2019-09-18 Last modified: 2019-12-04 Method: ELECTRON MICROSCOPY (3 Å) Cite: Transferrin receptor binds virus capsid with dynamic motion. Proc.Natl.Acad.Sci.USA, 116, 2019
7CA5	Cryo-EM structure of human GABA(B) receptor in apo state Descriptor: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2 Authors: Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. Deposit date: 2020-06-08 Release date: 2020-11-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (7.6 Å) Cite: Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
8EQI	Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with cyclopeptide des4.2.0 Descriptor: Cyclopeptide des4.2.0, Hdac6 protein, POTASSIUM ION, ... Authors: Watson, P.R, Christianson, D.W. Deposit date: 2022-10-07 Release date: 2023-04-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6. Acs Chem.Biol., 18, 2023
7CFM	Cryo-EM structure of the P395-bound GPBAR-Gs complex Descriptor: 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... Authors: Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. Deposit date: 2020-06-27 Release date: 2020-09-09 Last modified: 2020-12-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
8EYW	Beetroot dimer bound to ThT Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, POTASSIUM ION, RNA (49-MER) Authors: Passalacqua, L.F.M, Ferre-D'Amare, A.R. Deposit date: 2022-10-28 Release date: 2023-05-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun, 14, 2023
8ERL	CryoEM Structure of Lipoprotein Lipase Dimer Descriptor: Lipoprotein lipase Authors: Gunn, K.H, Neher, S.B. Deposit date: 2022-10-12 Release date: 2023-05-03 Last modified: 2023-05-17 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of dimeric lipoprotein lipase reveals a pore adjacent to the active site. Nat Commun, 14, 2023

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