5YE4
| Crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment | Descriptor: | 1A9D7 L chain, 1A9D7 VH CH1 chain, ZINC ION, ... | Authors: | Matsuda, T, Ito, T, Wakamori, M, Umehara, T. | Deposit date: | 2017-09-15 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13, 2018
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8K3A
| SOD1 and Nanobody2 complex | Descriptor: | NB2, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Cheng, S. | Deposit date: | 2023-07-14 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | SOD1 and Nanobody1 complex To Be Published
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8K3L
| SOD1 and Nanobody3 complex | Descriptor: | COPPER (II) ION, NB3, Superoxide dismutase [Cu-Zn], ... | Authors: | Cheng, S, Liu, R, Ding, Y. | Deposit date: | 2023-07-16 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | SOD1 and Nanobody1 complex To Be Published
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8K33
| SOD1 and Nanobody1 complex | Descriptor: | NB1, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Cheng, S. | Deposit date: | 2023-07-14 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | SOD1 and Nanobody1 complex To Be Published
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1DY5
| Deamidated derivative of bovine pancreatic ribonuclease | Descriptor: | ACETATE ION, ISOPROPYL ALCOHOL, RIBONUCLEASE A, ... | Authors: | Esposito, L, Vitagliano, L, Sica, F, Zagari, A, Mazzarella, L. | Deposit date: | 2000-01-27 | Release date: | 2000-03-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (0.87 Å) | Cite: | The Ultrahigh Resolution Crystal Structure of Ribonuclease A Containing an Isoaspartyl Residue: Hydration and Sterochemical Analysis. J.Mol.Biol., 297, 2000
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6IC7
| Human cathepsin-C in complex with dipeptidyl cyclopropyl nitrile inhibitor 3 | Descriptor: | 1-azanyl-~{N}-[(1~{R},2~{R})-1-cyano-2-[4-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]cyclopropyl]cyclohexane-1-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Hakansson, M, Logan, D.T, Korkmaz, B, Lesner, A, Wysocka, M, Gieldon, A, Gauthier, F, Jenne, D, Lauritzen, C, Pedersen, J. | Deposit date: | 2018-12-02 | Release date: | 2019-04-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C. Biochem. Pharmacol., 164, 2019
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5YCO
| Complex structure of PCNA with UHRF2 | Descriptor: | E3 ubiquitin-protein ligase UHRF2, GLYCEROL, Proliferating cell nuclear antigen, ... | Authors: | Wu, M, Chen, W, Hang, T, Wang, C, Zhang, X, Zang, J. | Deposit date: | 2017-09-07 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA. Biochem. Biophys. Res. Commun., 494, 2017
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4WI4
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation S254A | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | Deposit date: | 2014-09-25 | Release date: | 2015-09-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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4WI9
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A/H310A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, ... | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | Deposit date: | 2014-09-25 | Release date: | 2015-09-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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5YE3
| Crystal structure of the complex of di-acetylated histone H4 and 2A7D9 Fab fragment | Descriptor: | 2A7D9 L chain, 2A7D9 VH CH1 chain, di-acetylated histone H4 | Authors: | Matsuda, T, Ito, T, Wakamori, M, Umehara, T. | Deposit date: | 2017-09-15 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13, 2018
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1DCL
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6IC6
| Human cathepsin-C in complex with cyclopropyl peptidyl nitrile inhibitor 1 | Descriptor: | (2~{S})-~{N}-[(1~{R},2~{R})-1-(aminomethyl)-2-[4-[4-(trifluoromethyl)phenyl]phenyl]cyclopropyl]-2-azanyl-butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Hakansson, M, Logan, D.T, Korkmaz, B, Lesner, A, Wysocka, M, Gieldon, A, Gauthier, F, Jenne, D, Lauritzen, C, Pedersen, J. | Deposit date: | 2018-12-02 | Release date: | 2019-04-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C. Biochem. Pharmacol., 164, 2019
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1H0T
| An affibody in complex with a target protein: structure and coupled folding | Descriptor: | IMMUNOGLOBULIN G BINDING PROTEIN A, ZSPA-1 AFFIBODY | Authors: | Wahlberg, E, Lendel, C, Helgstrand, M, Allard, P, Dincbas-Renqvist, V, Hedqvist, A, Berglund, H, Nygren, P.-A, Hard, T. | Deposit date: | 2002-06-27 | Release date: | 2003-02-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | An Affibody in Complex with a Target Protein: Structure and Coupled Folding Proc.Natl.Acad.Sci.USA, 100, 2003
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5YPZ
| Crystal structure of minor pilin CofB from CFA/III complexed with N-terminal peptide fragment of CofJ | Descriptor: | CofB, CofJ | Authors: | Oki, H, Kawahara, K, Maruno, T, Imai, T, Muroga, Y, Fukakusa, S, Iwashita, T, Kobayashi, Y, Matsuda, S, Kodama, T, Iida, T, Yoshida, T, Ohkubo, T, Nakamura, S. | Deposit date: | 2017-11-04 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.521 Å) | Cite: | Interplay of a secreted protein with type IVb pilus for efficient enterotoxigenicEscherichia colicolonization. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1H2O
| SOLUTION STRUCTURE OF THE MAJOR CHERRY ALLERGEN PRU AV 1 MUTANT E45W | Descriptor: | MAJOR ALLERGEN PRU AV 1 | Authors: | Neudecker, P, Lehmann, K, Nerkamp, J, Schweimer, K, Sticht, H, Boehm, M, Scheurer, S, Vieths, S, Roesch, P. | Deposit date: | 2002-08-12 | Release date: | 2003-08-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mutational Epitope Analysis of Pru Av 1 and Api G 1, the Major Allergens of Cherry (Prunus Avium) and Celery (Apium Graveolens): Correlating Ige Reactivity with Three-Dimensional Structure Biochem.J., 376, 2003
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5FF6
| Cetuximab Fab in complex with L10Q meditope variant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ... | Authors: | Bzymek, K.P, Williams, J.C. | Deposit date: | 2015-12-17 | Release date: | 2016-10-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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5EK5
| STRUCTURAL CHARACTERIZATION OF IRMA FROM ESCHERICHIA COLI | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | Authors: | Heras, B, Moriel, D.G, Paxman, J.J, Schembri, M.A. | Deposit date: | 2015-11-03 | Release date: | 2016-03-09 | Last modified: | 2016-07-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein. Mbio, 7, 2016
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4WI3
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | Deposit date: | 2014-09-25 | Release date: | 2015-09-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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4WI6
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation N434A | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | Authors: | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | Deposit date: | 2014-09-25 | Release date: | 2015-09-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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1D1U
| USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS | Descriptor: | DNA (5'-D(*AP*CP*GP*GP*CP*AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*TP*G)-3'), PROTEIN (REVERSE TRANSCRIPTASE) | Authors: | Cote, M.L, Yohannan, S, Georgiadis, M.M. | Deposit date: | 1999-09-21 | Release date: | 2000-04-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs. Acta Crystallogr.,Sect.D, 56, 2000
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6KA7
| The complex structure of Human IgG Fc and its binding Repebody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, repebody | Authors: | Choi, J, Kim, H. | Deposit date: | 2019-06-21 | Release date: | 2020-06-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The complex structure of Human IgG Fc and its binding Repebody To Be Published
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1CG2
| CARBOXYPEPTIDASE G2 | Descriptor: | CARBOXYPEPTIDASE G2, ZINC ION | Authors: | Rowsell, S, Pauptit, R.A, Tucker, A.D, Melton, R.G, Blow, D.M, Brick, P. | Deposit date: | 1996-12-20 | Release date: | 1997-12-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy. Structure, 5, 1997
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5EGC
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4X7D
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5WC8
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