5YE4
Crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment
Summary for 5YE4
Entry DOI | 10.2210/pdb5ye4/pdb |
Descriptor | 1A9D7 VH CH1 chain, 1A9D7 L chain, di-acetylated histone H4, ... (5 entities in total) |
Functional Keywords | antibody, histone, complex, nuclear protein |
Biological source | Mus musculus More |
Total number of polymer chains | 6 |
Total formula weight | 96832.36 |
Authors | Matsuda, T.,Ito, T.,Wakamori, M.,Umehara, T. (deposition date: 2017-09-15, release date: 2018-08-22, Last modification date: 2023-11-22) |
Primary citation | Handoko, L.,Kaczkowski, B.,Hon, C.C.,Lizio, M.,Wakamori, M.,Matsuda, T.,Ito, T.,Jeyamohan, P.,Sato, Y.,Sakamoto, K.,Yokoyama, S.,Kimura, H.,Minoda, A.,Umehara, T. JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13:410-431, 2018 Cited by PubMed: 30080437DOI: 10.1080/15592294.2018.1469891 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.799 Å) |
Structure validation
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