4YDP
 
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6AR4
 | | Crystal structure of PICK1 in complex with the small molecule inhibitor 1o | | Descriptor: | N-[4-(4-bromophenyl)-1-{[2-(trifluoromethyl)phenyl]methyl}piperidine-4-carbonyl]-3-cyclopropyl-L-alanine, PRKCA-binding protein | | Authors: | Marcotte, D. | | Deposit date: | 2017-08-21 | | Release date: | 2018-08-22 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.
Sci Rep, 8, 2018
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4G69
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6EZI
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6ESP
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7MFW
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6BJO
 | | PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. | | Descriptor: | (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein | | Authors: | Marcotte, D.J. | | Deposit date: | 2017-11-06 | | Release date: | 2018-01-10 | | Last modified: | 2018-02-28 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.
Protein Sci., 27, 2018
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6BJN
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4GVD
 | | Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide | | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ... | | Authors: | Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J. | | Deposit date: | 2012-08-30 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
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4Z33
 | | Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2 | | Descriptor: | ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ... | | Authors: | Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P. | | Deposit date: | 2015-03-30 | | Release date: | 2016-06-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
To Be Published
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6GBE
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4GVC
 | | Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with phosphorylated Syndecan1 Peptide | | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ... | | Authors: | Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J. | | Deposit date: | 2012-08-30 | | Release date: | 2013-03-13 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
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4HOP
 | | Crystal structure of the computationally designed NNOS-Syntrophin complex | | Descriptor: | Alpha-1-syntrophin, Nitric oxide synthase, brain | | Authors: | Harwood, I.M, Melero, C, Ollikainen, N, Kortemme, T. | | Deposit date: | 2012-10-22 | | Release date: | 2013-11-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4YYX
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5A2P
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4Z8J
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6BXG
 | | 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. | | Descriptor: | CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ... | | Authors: | Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-12-18 | | Release date: | 2018-01-03 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide.
To Be Published
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7NTJ
 | | PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex | | Descriptor: | Envelope small membrane protein, MAGUK p55 subfamily member 5 | | Authors: | Javorsky, A, Kvansakul, M. | | Deposit date: | 2021-03-10 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
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7NTK
 | | PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ... | | Authors: | Javorsky, A, Kvansakul, M. | | Deposit date: | 2021-03-10 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
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6GBD
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4H11
 | | Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy | | Descriptor: | ACETATE ION, Disks large homolog 2, SULFATE ION | | Authors: | Fiorentini, M, Kastrup, J.S, Gajhede, M. | | Deposit date: | 2012-09-10 | | Release date: | 2013-04-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy.
Acta Crystallogr.,Sect.D, 69, 2013
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7CQF
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7E0B
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7D6F
 | | The crystal structure of ARMS-PBM/MAGI2-PDZ4 | | Descriptor: | GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ... | | Authors: | Ye, J, Zhang, Y, Zhong, Z, Wang, C. | | Deposit date: | 2020-09-30 | | Release date: | 2020-11-04 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode.
Neurochem.Int., 149, 2021
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7FSV
 | | SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 | | Descriptor: | 1,2-ETHANEDIOL, ALANINE, D-GLUTAMIC ACID, ... | | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | Deposit date: | 2023-01-24 | | Release date: | 2023-02-15 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | SDCBP PanDDA analysis group deposition
To Be Published
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