5RZG
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![BU of 5rzg by Molmil](/molmil-images/mine/5rzg) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z133729708 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZW
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![BU of 5rzw by Molmil](/molmil-images/mine/5rzw) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2574937229 | Descriptor: | (S)-1-(4-methoxyphenyl)-1-phenylmethanamine, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZ9
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![BU of 5rz9 by Molmil](/molmil-images/mine/5rz9) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z943693514 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZP
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![BU of 5rzp by Molmil](/molmil-images/mine/5rzp) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z33546965 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RYN
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![BU of 5ryn by Molmil](/molmil-images/mine/5ryn) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1545312521 | Descriptor: | (2S)-N-(3-chloro-2-methylphenyl)oxolane-2-carboxamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RYW
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![BU of 5ryw by Molmil](/molmil-images/mine/5ryw) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434829 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZC
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![BU of 5rzc by Molmil](/molmil-images/mine/5rzc) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z300245038 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZT
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![BU of 5rzt by Molmil](/molmil-images/mine/5rzt) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z763030030 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RYU
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![BU of 5ryu by Molmil](/molmil-images/mine/5ryu) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1545196403 | Descriptor: | 1,2-ETHANEDIOL, 2-fluoro-N-[(1H-pyrazol-3-yl)methyl]aniline, DIMETHYL SULFOXIDE, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZ3
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![BU of 5rz3 by Molmil](/molmil-images/mine/5rz3) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1259341037 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZQ
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![BU of 5rzq by Molmil](/molmil-images/mine/5rzq) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z100642432 | Descriptor: | 1,2-ETHANEDIOL, 2-bromo-4-fluoro-N,N-dimethylbenzamide, DIMETHYL SULFOXIDE, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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5RZ7
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![BU of 5rz7 by Molmil](/molmil-images/mine/5rz7) | EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z57472297 | Descriptor: | 1,2-ETHANEDIOL, 1-[2-methyl-1,3-bis(oxidanyl)propan-2-yl]-3-phenyl-urea, DIMETHYL SULFOXIDE, ... | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2020-10-30 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | EPB41L3 PanDDA analysis group deposition To Be Published
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7C3M
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![BU of 7c3m by Molmil](/molmil-images/mine/7c3m) | Structure of FERM protein | Descriptor: | Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3 | Authors: | Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G. | Deposit date: | 2020-05-13 | Release date: | 2020-06-03 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state. Plos Biol., 18, 2020
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7BYJ
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![BU of 7byj by Molmil](/molmil-images/mine/7byj) | Crystal structure of the FERM domain of FRMPD4 | Descriptor: | FERM and PDZ domain-containing protein 4 | Authors: | Lin, L, Wang, M, Wang, C, Zhu, J. | Deposit date: | 2020-04-23 | Release date: | 2020-12-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability. Biochem.J., 477, 2020
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6XTJ
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![BU of 6xtj by Molmil](/molmil-images/mine/6xtj) | The high resolution structure of the FERM domain of human FERMT2 | Descriptor: | CITRIC ACID, Fermitin family homolog 2,Fermitin family homolog 2,Fermitin family homolog 2 | Authors: | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-16 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The high resolution structure of the FERM domain of human FERMT2 To Be Published
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6TY3
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![BU of 6ty3 by Molmil](/molmil-images/mine/6ty3) | FAK structure from single particle analysis of 2D crystals | Descriptor: | Focal adhesion kinase 1 | Authors: | Acebron, I, Righetto, R, Biyani, N, Chami, M, Boskovic, J, Stahlberg, H, Lietha, D. | Deposit date: | 2020-01-15 | Release date: | 2020-08-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (6.32 Å) | Cite: | Structural basis of Focal Adhesion Kinase activation on lipid membranes. Embo J., 39, 2020
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6TY4
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![BU of 6ty4 by Molmil](/molmil-images/mine/6ty4) | FAK structure with AMP-PNP from single particle analysis of 2D crystals | Descriptor: | Focal adhesion kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Acebron, I, Righetto, R, Biyani, N, Chami, M, Boskovic, J, Stahlberg, H, Lietha, D. | Deposit date: | 2020-01-15 | Release date: | 2020-08-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (5.96 Å) | Cite: | Structural basis of Focal Adhesion Kinase activation on lipid membranes. Embo J., 39, 2020
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6TXS
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![BU of 6txs by Molmil](/molmil-images/mine/6txs) | The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide | Descriptor: | CD44 antigen, Moesin | Authors: | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-14 | Release date: | 2020-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
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6TXQ
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![BU of 6txq by Molmil](/molmil-images/mine/6txq) | The high resolution structure of the FERM domain and helical linker of human moesin | Descriptor: | ACETATE ION, Moesin | Authors: | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-14 | Release date: | 2020-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
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6VGU
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![BU of 6vgu by Molmil](/molmil-images/mine/6vgu) | |
6V97
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![BU of 6v97 by Molmil](/molmil-images/mine/6v97) | Kindlin-3 double deletion mutant short form | Descriptor: | Fermitin family homolog 3 | Authors: | Xu, Z, Zhang, T.L, Xu, Z, Sun, J.J, Ding, J.P, Ma, Y.Q. | Deposit date: | 2019-12-13 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.381 Å) | Cite: | Structure basis of the FERM domain of kindlin-3 in supporting integrin alpha IIb beta 3 activation in platelets. Blood Adv, 4, 2020
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6V9G
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![BU of 6v9g by Molmil](/molmil-images/mine/6v9g) | Kindlin-3 double deletion mutant long form | Descriptor: | Fermitin family homolog 3 | Authors: | Xu, Z, Zhang, T.L, Xu, Z, Sun, J.J, Ding, J.P, Ma, Y.Q. | Deposit date: | 2019-12-13 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure basis of the FERM domain of kindlin-3 in supporting integrin alpha IIb beta 3 activation in platelets. Blood Adv, 4, 2020
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6UZK
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![BU of 6uzk by Molmil](/molmil-images/mine/6uzk) | |
6T36
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![BU of 6t36 by Molmil](/molmil-images/mine/6t36) | Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide | Descriptor: | BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3 | Authors: | Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C. | Deposit date: | 2019-10-10 | Release date: | 2021-01-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein. Sci Rep, 11, 2021
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6U4K
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![BU of 6u4k by Molmil](/molmil-images/mine/6u4k) | Human talin2 residues 1-403 | Descriptor: | Talin-2 | Authors: | Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. | Deposit date: | 2019-08-26 | Release date: | 2020-07-08 | Last modified: | 2020-09-23 | Method: | X-RAY DIFFRACTION (2.555 Å) | Cite: | A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
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