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6QPG
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BU of 6qpg by Molmil
Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205
Descriptor: Nanobody NB8205, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M.
Deposit date:2019-02-13
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6ABI
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BU of 6abi by Molmil
The apo-structure of D-lactate dehydrogenase from Fusobacterium nucleatum
Descriptor: D-lactate dehydrogenase, GLYCEROL, SULFATE ION
Authors:Furukawa, N, Miyanaga, A, Nakajima, M, Taguchi, H.
Deposit date:2018-07-21
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Sequential Allosteric Transitions in Tetrameric d-Lactate Dehydrogenases from Three Gram-Negative Bacteria
Biochemistry, 57, 2018
6ABJ
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BU of 6abj by Molmil
The apo-structure of D-lactate dehydrogenase from Pseudomonas aeruginosa
Descriptor: ACETATE ION, D-lactate dehydrogenase (Fermentative)
Authors:Furukawa, N, Miyanaga, A, Nakajima, M, Taguchi, H.
Deposit date:2018-07-21
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Basis of Sequential Allosteric Transitions in Tetrameric d-Lactate Dehydrogenases from Three Gram-Negative Bacteria
Biochemistry, 57, 2018
6QXE
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BU of 6qxe by Molmil
Influenza A virus (A/NT/60/1968) polymerase dimer of hetermotrimer in complex with 3'5' cRNA promoter and Nb8205
Descriptor: Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
Deposit date:2019-03-07
Release date:2019-09-04
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6QX8
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BU of 6qx8 by Molmil
Influenza A virus (A/NT/60/1968) polymerase dimer of heterotrimer in complex with 5' cRNA promoter
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*CP*AP*AP*AP*AP*GP*CP*AP*GP*A)-3'), ...
Authors:Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
Deposit date:2019-03-07
Release date:2019-09-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
8DVX
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BU of 8dvx by Molmil
Structure of acetylated Pig somatic Cytochrome c (Aly39) at 1.5A
Descriptor: Cytochrome c, HEME C, HEXACYANOFERRATE(3-)
Authors:Edwards, B.F.P, Huettemann, M, Vaishnav, A, Brunzelle, J, Morse, P, Wan, J.
Deposit date:2022-07-30
Release date:2023-07-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Nat Commun, 14, 2023
8DZL
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BU of 8dzl by Molmil
Structure of the K39Q mutant of rat somatic Cytochrome c at 1.36A
Descriptor: Cytochrome c, somatic, HEME C
Authors:Edwards, B.F.P, Huettemann, M, Vaishnav, A, Brunzelle, J, Morse, P, Wan, J.
Deposit date:2022-08-08
Release date:2023-07-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Nat Commun, 14, 2023
6RR7
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BU of 6rr7 by Molmil
Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ...
Authors:Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
Deposit date:2019-05-17
Release date:2019-09-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
7DL5
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BU of 7dl5 by Molmil
Crystal structure of Thermotoga Maritima ferritin mutant at 2.3 Angstrom resolution
Descriptor: FE (III) ION, Ferritin, MAGNESIUM ION
Authors:Liu, Y, Leng, X, Zang, J, Zhao, G.
Deposit date:2020-11-26
Release date:2021-12-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A short helix regulates conversion of dimeric and 24-meric ferritin architectures.
Int.J.Biol.Macromol., 203, 2022
6SAW
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BU of 6saw by Molmil
Chromophore binding domain of bacteriophytochrome linked diguanylyl cyclase from Idiomarina species A28L (dimeric Pfr-like state).
Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, CHLORIDE ION, Diguanylate cyclase (GGDEF) domain-containing protein
Authors:Gourinchas, G, Winkler, A.
Deposit date:2019-07-18
Release date:2019-12-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Distinct chromophore-protein environments enable asymmetric activation of a bacteriophytochrome-activated diguanylate cyclase.
J.Biol.Chem., 295, 2020
1XD5
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BU of 1xd5 by Molmil
Crystal structures of novel monomeric monocot mannose-binding lectins from Gastrodia elata
Descriptor: SULFATE ION, antifungal protein GAFP-1
Authors:Liu, W, Yang, N, Wang, M, Huang, R.H, Hu, Z, Wang, D.C.
Deposit date:2004-09-04
Release date:2005-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Mechanism Governing the Quaternary Organization of Monocot Mannose-binding Lectin Revealed by the Novel Monomeric Structure of an Orchid Lectin
J.Biol.Chem., 280, 2005
1XD6
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BU of 1xd6 by Molmil
Crystal structures of novel monomeric monocot mannose-binding lectins from Gastrodia elata
Descriptor: SULFATE ION, gastrodianin-4
Authors:Liu, W, Yang, N, Wang, M, Huang, R.H, Hu, Z, Wang, D.C.
Deposit date:2004-09-04
Release date:2005-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Mechanism Governing the Quaternary Organization of Monocot Mannose-binding Lectin Revealed by the Novel Monomeric Structure of an Orchid Lectin
J.Biol.Chem., 280, 2005
6VA7
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BU of 6va7 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase P396L mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VA8
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BU of 6va8 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase F381L mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VA9
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BU of 6va9 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase R393H mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VA0
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BU of 6va0 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase W509A mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-16
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6YCS
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BU of 6ycs by Molmil
Human Transcription Cofactor PC4 DNA-binding domain in complex with full phosphorothioate 5-10-5 2'-O-methyl DNA gapmer antisense oligonucleotide.
Descriptor: DNA (5'-D(P*(OKQ))-D(P*(OKT))-R(P*(RFJ))-D(*(OKQ)P*(OKT)P*(AS)P*(GS)P*(OKN)P*(OKN)P*(PST)P*(OKN)P*(PST)P*(GS)P*(GS)P*(AS)P*(OKT)P*(OKT))-3'), PC4 protein, SODIUM ION, ...
Authors:Hyjek-Skladanowska, M, Vickers, T.A, Napiorkowska, A, Anderson, B, Tanowitz, M, Crooke, S.T, Liang, X, Seth, P.P, Nowotny, M.
Deposit date:2020-03-19
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins.
J.Am.Chem.Soc., 142, 2020
6TMR
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BU of 6tmr by Molmil
Mokola virus glycoprotein, monomeric post-fusion conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, TERBIUM(III) ION
Authors:Belot, L, Roche, S, Legrand, P, Gaudin, Y, Albertini, A.
Deposit date:2019-12-05
Release date:2020-02-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:Crystal structure of Mokola virus glycoprotein in its post-fusion conformation.
Plos Pathog., 16, 2020
6BSY
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BU of 6bsy by Molmil
HIV-1 Rev assembly domain (residues 1-69)
Descriptor: PHOSPHATE ION, Protein Rev
Authors:Watts, N.R, Eren, E, Zhuang, X, Wang, Y.X, Steven, A.C, Wingfield, P.T.
Deposit date:2017-12-04
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export.
J. Struct. Biol., 203, 2018
6VAQ
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BU of 6vaq by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase V394L mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6CK2
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BU of 6ck2 by Molmil
Insulin analog containing a YB26W mutation
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Rege, N.K, Yee, V.C, Weiss, M.A.
Deposit date:2018-02-27
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-based stabilization of insulin as a therapeutic protein assembly via enhanced aromatic-aromatic interactions.
J. Biol. Chem., 293, 2018
4RUV
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BU of 4ruv by Molmil
Crystal structure of thioredoxin 2 from Staphylococcus aureus NCTC8325
Descriptor: Thioredoxin
Authors:Bose, M, Biswas, R, Roychowdhury, A, Bhattacharyya, S, Ghosh, A.K, Das, A.K.
Deposit date:2014-11-22
Release date:2015-12-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Elucidation of the mechanism of disulfide exchange between staphylococcal thioredoxin2 and thioredoxin reductase2: A structural insight.
Biochimie, 160, 2019
2FH5
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BU of 2fh5 by Molmil
The Structure of the Mammalian SRP Receptor
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Signal recognition particle receptor alpha subunit, ...
Authors:Schlenker, O, Wild, K, Sinning, I.
Deposit date:2005-12-23
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains.
J.Biol.Chem., 281, 2006
5DK0
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BU of 5dk0 by Molmil
Fc Heterodimer Design 20.8.34 Y349S/T366M/K370Y/K409V + E356G/E357D/S364Q/Y407A
Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-02
Release date:2016-03-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
4UXR
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BU of 4uxr by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014

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