PDB: 870 resultsInfo pagesStatus searchChemie searchBIRD

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7TYS	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the up conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-14 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7TYT	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-14 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1E	CryoEM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the down conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-21 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (4.52 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1Q	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-21 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7X07	Cryo-EM structure of human ABCD1 in the presence of C26:0 Descriptor: ATP-binding cassette sub-family D member 1, hexacosanoic acid Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-21 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7U1S	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-22 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7X0Z	Cryo-EM structure of human ABCD1 E630Q in the presence of ATP and Magnesium in outward-facing state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1, MAGNESIUM ION Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-22 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7X0T	Cryo-EM structure of human ABCD1 E630Q in the presence of C26:0-CoA and ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1, OCTANOYL-COENZYME A Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-22 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7X0Q	Crystal structure of ATPase Clo1313_2554 from Clostridium thermocellum Descriptor: ABC transporter related protein Authors: Dong, S, Yao, X, Feng, Y. Deposit date: 2022-02-22 Release date: 2022-09-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Deciphering Cellodextrin and Glucose Uptake in Clostridium thermocellum. Mbio, 13, 2022
7U24	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-23 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7Z19	E. coli C-P lyase bound to a single PhnK ABC domain Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... Authors: Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. Deposit date: 2022-02-24 Release date: 2022-05-25 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (2.57 Å) Cite: Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
7Z18	E. coli C-P lyase bound to a PhnK ABC dimer and ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, ... Authors: Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. Deposit date: 2022-02-24 Release date: 2022-05-25 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (1.98 Å) Cite: Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
7Z17	E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... Authors: Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. Deposit date: 2022-02-24 Release date: 2022-05-25 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (2.57 Å) Cite: Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
7Z16	E. coli C-P lyase bound to PhnK/PhnL dual ABC dimer with AMPPNP and PhnK E171Q mutation Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI, ... Authors: Amstrup, S.K, Sofus, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. Deposit date: 2022-02-24 Release date: 2022-06-22 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (2.09 Å) Cite: Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
7Z15	E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ... Authors: Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E. Deposit date: 2022-02-24 Release date: 2022-06-22 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (1.93 Å) Cite: Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase. Nat Commun, 14, 2023
7X1W	Cryo-EM structure of human ABCD1 E630Q in the presence of ATP in inward-facing state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1 Authors: Chao, X, Li-Na, J, Lin, T. Deposit date: 2022-02-24 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP. Signal Transduct Target Ther, 8, 2023
7U2X	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-02-25 Release date: 2022-08-31 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U6Y	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-03-06 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (7.4 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U7M	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-03-07 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7UAA	CryoEM structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state with Kir6.2-CTD in the up conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 Authors: Shyng, S.L, Sung, M.W, Driggers, C.M. Deposit date: 2022-03-11 Release date: 2022-08-31 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7ZDF	IF(heme/confined) conformation of CydDC in AMP-PNP(CydD) bound state (Dataset-4) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDU	Occ(apo/return) conformation of CydDC mutant (E500Q.C) in ATP(CydC)/ATP(CydD) bound state (Dataset-19) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDC	IF(heme/confined) conformation of CydDC in ADP(CydD) bound state (Dataset-3) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDA	IF(apo/asym) conformation of CydDC in ADP+Pi(CydC)/ATP(CydD) bound state (Dataset-2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding/permease protein CydC, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023
7ZDK	IF(apo/asym) conformation of CydDC in AMP-PNP(CydC)/AMP-PNP(CydD) bound state (Dataset-8) Descriptor: ATP-binding/permease protein CydC, ATP-binding/permease protein CydD, MAGNESIUM ION, ... Authors: Wu, D, Safarian, S. Deposit date: 2022-03-29 Release date: 2023-04-19 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Dissecting the conformational complexity and mechanism of a bacterial heme transporter. Nat.Chem.Biol., 19, 2023

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