7X0T

Cryo-EM structure of human ABCD1 E630Q in the presence of C26:0-CoA and ATP

Summary for 7X0T

• Entry DOI: 10.2210/pdb7x0t/pdb
• EMDB information: 32924
• Descriptor: ATP-binding cassette sub-family D member 1, OCTANOYL-COENZYME A, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: membrane protein, ligand, complex, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 171789.16

Authors

Chao, X.,Li-Na, J.,Lin, T. (deposition date: 2022-02-22, release date: 2023-03-22, Last modification date: 2024-06-26)

• Primary citation: Xiong, C.,Jia, L.N.,Xiong, W.X.,Wu, X.T.,Xiong, L.L.,Wang, T.H.,Zhou, D.,Hong, Z.,Liu, Z.,Tang, L.; Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.; Signal Transduct Target Ther, 8:74-74, 2023; PubMed: 36810450; DOI: 10.1038/s41392-022-01280-9

Experimental method

ELECTRON MICROSCOPY (3.3 Å)