7X0T
Cryo-EM structure of human ABCD1 E630Q in the presence of C26:0-CoA and ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | ATP-binding cassette sub-family D member 1 | polymer | 763 | 85194.1 | 2 | UniProt (P33897) Pfam (PF06472) Pfam (PF00005) In PDB | Homo sapiens (human) | Adrenoleukodystrophy protein,ALDP |
2 | A | OCTANOYL-COENZYME A | non-polymer | 893.7 | 1 | Chemie (CO8) | |||
3 | B | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A, B: 1 - 745 (UniProt: P33897)
PDB | External Database | Details |
---|---|---|
Met -17 | - | initiating methionine |
Asp -16 | - | expression tag |
Tyr -15 | - | expression tag |
Lys -14 | - | expression tag |
Asp -13 | - | expression tag |
Asp -12 | - | expression tag |
Asp -11 | - | expression tag |
Asp -10 | - | expression tag |
Lys -9 | - | expression tag |
Gly -8 | - | expression tag |
Ser -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Gln 630 | Glu 630 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 170388.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1400.9 | |
All* | Total formula weight | 171789.2 |