PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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4DTU	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-02-21 Release date: 2012-06-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
8B8V	Crystal structure of the Rabies virus RNA free nucleoprotein- phosphoprotein complex Descriptor: DI(HYDROXYETHYL)ETHER, Nucleoprotein, Phosphoprotein Authors: Gerard, F.C.A, Jamin, M, Bourhis, J.M. Deposit date: 2022-10-05 Release date: 2023-03-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module. Viruses, 14, 2022
4DTN	RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-02-21 Release date: 2012-06-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTS	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... Authors: Xia, S, Wang, J, Konigsberg, W.H. Deposit date: 2012-02-21 Release date: 2012-06-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
1Q1H	An extended winged helix domain in general transcription factor E/IIE alpha Descriptor: Transcription Factor E Authors: Meinhart, A, Blobel, J, Cramer, P. Deposit date: 2003-07-21 Release date: 2003-12-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: An Extended Winged Helix Domain in General Transcription Factor E/IIE alpha J.Biol.Chem., 278, 2003
5V3H	Crystal structure of SMYD2 with SAM and EPZ033294 Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Boriack-Sjodin, P.A. Deposit date: 2017-03-07 Release date: 2018-04-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation. Plos One, 13, 2018
3TN9	X-ray structure of the HRV2 empty capsid (B-particle) Descriptor: Protein VP1, Protein VP2, Protein VP3 Authors: Garriga, D, Pickl-Herk, A, Luque, D, Wruss, J, Caston, J.R, Blaas, D, Verdaguer, N. Deposit date: 2011-09-01 Release date: 2012-03-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Insights into minor group rhinovirus uncoating: the X-ray structure of the HRV2 empty capsid. Plos Pathog., 8, 2012
2OUG	Crystal structure of the RfaH transcription factor at 2.1A resolution Descriptor: Transcriptional activator rfaH Authors: Vassylyev, D.G, Vassylyeva, M.N, Svetlov, V, Artsimovitch, I. Deposit date: 2007-02-10 Release date: 2007-05-01 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for converting a general transcription factor into an operon-specific virulence regulator. Mol.Cell, 26, 2007
6CKX	Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide Descriptor: Cyclin-K, Cyclin-dependent kinase 12, MAGNESIUM ION, ... Authors: Klein, M.G. Deposit date: 2018-03-01 Release date: 2018-08-29 Last modified: 2018-09-26 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors. J. Med. Chem., 61, 2018
8D33	Human mitochondrial DNA polymerase gamma ternary complex with GC basepair Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ... Authors: Park, J, Yin, Y.W. Deposit date: 2022-05-31 Release date: 2023-05-24 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (2.46 Å) Cite: Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30, 2023
3BLH	Crystal Structure of Human CDK9/cyclinT1 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell division protein kinase 9, Cyclin-T1 Authors: Baumli, S, Lolli, G, Lowe, E.D, Johnson, L.N. Deposit date: 2007-12-11 Release date: 2008-07-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.48 Å) Cite: The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation Embo J., 27, 2008
7M09	Pre-catalytic quaternary complex of DNA Polymerase Lambda with blunt-ended DSB substrate and incoming dUMPNPP Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining. Nat Commun, 13, 2022
7M0D	Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound complementary DSB substrate and incoming dUMPNPP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining. Nat Commun, 13, 2022
7M0B	Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound mismatched DSB and incoming dUMPNPP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining. Nat Commun, 13, 2022
3BLR	Crystal Structure of Human CDK9/cyclinT1 in complex with Flavopiridol Descriptor: 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, Cell division protein kinase 9, Cyclin-T1, ... Authors: Baumli, S, Lolli, G, Lowe, E.D, Johnson, L.N. Deposit date: 2007-12-11 Release date: 2008-07-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation Embo J., 27, 2008
4C0B	Structure of wild-type Clp1p-Pcf11p (454 -563) complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MRNA CLEAVAGE AND POLYADENYLATION FACTOR CLP1, ... Authors: Fribourg, S, Dupin, A.F. Deposit date: 2013-08-01 Release date: 2014-02-19 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Structural basis for ATP loss by Clp1p in a G135R mutant protein. Biochimie, 101, 2014
2IVX	Crystal structure of human cyclin T2 at 1.8 A resolution Descriptor: 1,2-ETHANEDIOL, CYCLIN-T2 Authors: Debreczeni, J.E, Bullock, A.N, Fedorov, O, Savitsky, P, Berridge, G, Das, S, Pike, A.C.W, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Gorrec, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. Deposit date: 2006-06-21 Release date: 2006-07-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation. EMBO J., 27, 2008
5HBM	Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase Descriptor: (7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MANGANESE (II) ION, ... Authors: Kirby, K.A, Sarafianos, S.G. Deposit date: 2015-12-31 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.043 Å) Cite: Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase To Be Published
6DU3	Structure of Scp1 D96N bound to REST-pS861/4 peptide Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861 Authors: Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. Deposit date: 2018-06-19 Release date: 2018-09-26 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). J. Biol. Chem., 293, 2018
6DU2	Structure of Scp1 D96N bound to REST-pS861/4 peptide Descriptor: MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2 Authors: Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. Deposit date: 2018-06-19 Release date: 2018-09-26 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). J. Biol. Chem., 293, 2018
3BLQ	Crystal Structure of Human CDK9/cyclinT1 in Complex with ATP Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Cell division protein kinase 9, ... Authors: Baumli, S, Lolli, G, Lowe, E.D, Johnson, L.N. Deposit date: 2007-12-11 Release date: 2008-07-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation Embo J., 27, 2008
3RBD	Dpo4 extension ternary complex with 3'-terminal primer C base opposite the 3-methylcytosine (m3c) lesion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... Authors: Rechkoblit, O, Patel, D.J. Deposit date: 2011-03-29 Release date: 2011-06-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure, 19, 2011
3RB4	Dpo4 extension ternary complex with 3'-terminal primer G base opposite the 3-methylcytosine (m3c) lesion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ... Authors: Rechkoblit, O, Patel, D.J. Deposit date: 2011-03-28 Release date: 2011-06-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.805 Å) Cite: Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure, 19, 2011
3RB6	Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 3-methylcytosine (m3c) lesion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... Authors: Rechkoblit, O, Patel, D.J. Deposit date: 2011-03-28 Release date: 2011-06-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure, 19, 2011
3RBE	Dpo4 extension ternary complex with 3'-terminal primer t base opposite the 3-methylcytosine (m3c) lesion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ... Authors: Rechkoblit, O, Patel, D.J. Deposit date: 2011-03-29 Release date: 2011-06-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure, 19, 2011

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