8WWY
| Crystal structure of mouse TIFA/TIFAB heterodimer | Descriptor: | (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B | Authors: | Nakamura, T. | Deposit date: | 2023-10-27 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA. Proc.Natl.Acad.Sci.USA, 121, 2024
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1FBI
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6M62
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4Q4N
| Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at H432 | Descriptor: | Peptidoglycan endopeptidase RipA | Authors: | Squeglia, F, Ruggiero, A, Romano, M, Vitagliano, L, Berisio, R. | Deposit date: | 2014-04-15 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: evidence for the L-to-D inversion of configuration of the catalytic cysteine. Acta Crystallogr.,Sect.D, 70, 2014
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4Q4T
| Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at E444 | Descriptor: | FORMIC ACID, GLYCEROL, Peptidoglycan endopeptidase RipA | Authors: | Squeglia, F, Ruggiero, A, Romano, M, Vitagliano, L, Berisio, R. | Deposit date: | 2014-04-15 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: evidence for the L-to-D inversion of configuration of the catalytic cysteine. Acta Crystallogr.,Sect.D, 70, 2014
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4Q4G
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3OJ8
| Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain | Descriptor: | (S)-[(2S)-6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl](5-pyridin-2-yl-1,3-oxazol-2-yl)methanol, CHLORIDE ION, Fatty-acid amide hydrolase 1 | Authors: | Mileni, M, Stevens, R.C, Boger, D.L. | Deposit date: | 2010-08-20 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain J.Med.Chem., 54, 2011
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8QRM
| mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-09 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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8QRL
| mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2 | Descriptor: | 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-09 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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8QRK
| mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-09 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (6.69 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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6Q1F
| Atomic structure of the Human Herpesvirus 6B Capsid and Capsid-Associated Tegument Complexes | Descriptor: | Large structural phosphoprotein, Major capsid protein, Small capsomere-interacting protein, ... | Authors: | Zhang, Y.B, Liu, W, Li, Z.H, Kumar, V, Alvarez-Cabrera, A.L, Leibovitch, E, Cui, Y.X, Mei, Y, Bi, G.Q, Jacobson, S, Zhou, Z.H. | Deposit date: | 2019-08-03 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes. Nat Commun, 10, 2019
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8QRN
| mt-SSU in GTPBP8 knock-out cells, state 4 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-09 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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8QMO
| Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. | Deposit date: | 2023-09-24 | Release date: | 2024-01-10 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
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7LVS
| The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide | Descriptor: | Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION | Authors: | Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E. | Deposit date: | 2021-02-26 | Release date: | 2021-07-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | The molecular basis of allostery in a facilitated dissociation process. Structure, 29, 2021
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2N9E
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1H6V
| Mammalian thioredoxin reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOREDOXIN REDUCTASE | Authors: | Sandalova, T, Zhong, L, Lindqvist, Y, Holmgren, A, Schneider, G. | Deposit date: | 2001-06-27 | Release date: | 2001-08-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Three-Dimensional Structure of a Mammalian Thioredoxin Reductase: Implication for Mechanism and Evolution of a Selenocysteine Dependent Enzyme Proc.Natl.Acad.Sci.USA, 98, 2001
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9PAP
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9B9L
| RPRD1B C-terminal interacting domain bound to a pThr4 CTD peptide | Descriptor: | Regulation of nuclear pre-mRNA domain-containing protein 1B, SER-PRO-THR-SER-PRO-SER-TYR-SER-PRO-TPO-SER-PRO-SER-TYR-SER | Authors: | Moreno, R.Y, Zhang, Y.J. | Deposit date: | 2024-04-02 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Thr4 phosphorylation primes Ser2 phosphorylation on RNA polymerase II and mediates regulation in elongation and 3'end processing To Be Published
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7P73
| The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 | Descriptor: | CALCIUM ION, GLYCEROL, Protein Tax-1, ... | Authors: | Gogl, G, Cousido-Siah, A, Trave, G. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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7P74
| The PDZ domain of SYNJ2BP complexed with the phosphorylated PDZ-binding motif of RSK1 | Descriptor: | CALCIUM ION, GLYCEROL, Ribosomal protein S6 kinase alpha-1, ... | Authors: | Gogl, G, Cousido-Siah, A, Trave, G. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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7P70
| The PDZ-domain of SNTB1 complexed with the PDZ-binding motif of HPV35-E6 | Descriptor: | Beta-1-syntrophin,Annexin A2, CALCIUM ION, GLYCEROL, ... | Authors: | Gogl, G, Cousido-Siah, A, Trave, G. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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7P72
| The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E | Descriptor: | CALCIUM ION, Envelope small membrane protein, GLYCEROL, ... | Authors: | Gogl, G, Cousido-Siah, A, Trave, G. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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6M6I
| Structure of HSV2 B-capsid portal vertex | Descriptor: | Coiled coils chain 1, Coiled coils chain 2, Major capsid protein, ... | Authors: | Wang, X.X, Wang, N. | Deposit date: | 2020-03-14 | Release date: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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6M6H
| Structure of HSV2 C-capsid portal vertex | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | Authors: | Wang, X.X, Wang, N. | Deposit date: | 2020-03-14 | Release date: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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6M6G
| Structure of HSV2 viron capsid portal vertex | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Coiled coils, ... | Authors: | Wang, X.X, Wang, N. | Deposit date: | 2020-03-14 | Release date: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (5.39 Å) | Cite: | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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