8PEN
| fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-14 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PIM
| fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-22 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PFG
| autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex), not fully complementary scaffold | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-15 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PIB
| autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-21 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PHK
| fully recruited RfaH bound to E. coli transcription complex paused at ops site | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | Deposit date: | 2023-06-20 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8ONE
| Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Asp190Ser mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose | Descriptor: | 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Mattoteia, D, De Marco, M, Pinnola, A, Faravelli, S, Scietti, L, Forneris, F. | Deposit date: | 2023-04-02 | Release date: | 2023-07-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of Regulatory Molecular "Hot Spots" for LH/PLOD Collagen Glycosyltransferase Activity. Int J Mol Sci, 24, 2023
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6G6R
| Human Methionine Adenosyltransferase II with SAMe and PPNP | Descriptor: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | Authors: | Panmanee, J, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2018-04-02 | Release date: | 2019-04-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Control and regulation of S-Adenosylmethionine biosynthesis by the regulatory beta subunit and quinolone-based compounds. Febs J., 286, 2019
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6OT2
| Structure of the TRPV3 K169A sensitized mutant in apo form at 4.1 A resolution | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y. | Deposit date: | 2019-05-02 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Regulatory switch at the cytoplasmic interface controls TRPV channel gating. Elife, 8, 2019
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6OT5
| Structure of the TRPV3 K169A sensitized mutant in the presence of 2-APB at 3.6 A resolution | Descriptor: | 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y. | Deposit date: | 2019-05-02 | Release date: | 2019-05-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Regulatory switch at the cytoplasmic interface controls TRPV channel gating. Elife, 8, 2019
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5E44
| Crystal structure of holo-FNR of A. fischeri | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FNR regulator, IRON/SULFUR CLUSTER | Authors: | Volbeda, A, Fontecilla-Camps, J.C. | Deposit date: | 2015-10-05 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium. Sci Adv, 1, 2015
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1QVP
| C terminal SH3-like domain from Diphtheria toxin Repressor residues 144-226. | Descriptor: | Diphtheria toxin repressor | Authors: | Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Marin, V, Bhattacharya, N, Love, J.F, Murphy, J.R, Logan, T.M. | Deposit date: | 2003-08-28 | Release date: | 2004-11-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry, 44, 2005
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6K4Y
| CryoEM structure of sigma appropriation complex | Descriptor: | 10 kDa anti-sigma factor, DNA (60-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Shi, J, Wen, A, Feng, Y. | Deposit date: | 2019-05-27 | Release date: | 2019-08-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Structural basis of sigma appropriation. Nucleic Acids Res., 47, 2019
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4YT2
| Hmd II from Methanocaldococcus jannaschii | Descriptor: | DI(HYDROXYETHYL)ETHER, H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338, TRIETHYLENE GLYCOL | Authors: | Fujishiro, T, Ermler, U, Shima, S. | Deposit date: | 2015-03-17 | Release date: | 2015-07-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Towards a functional identification of catalytically inactive [Fe]-hydrogenase paralogs. Febs J., 282, 2015
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6XNU
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6XNV
| CRYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES CBPB PROTEIN (LMO1009) IN COMPLEX WITH C-DI-AMP | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CBS domain-containing protein | Authors: | Luo, S, Tong, L. | Deposit date: | 2020-07-04 | Release date: | 2020-09-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes. Mbio, 11, 2020
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1QW1
| Solution Structure of the C-Terminal Domain of DtxR residues 110-226 | Descriptor: | Diphtheria toxin repressor | Authors: | Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Love, J.F, Murphy, J.R, Logan, T.M. | Deposit date: | 2003-08-29 | Release date: | 2005-03-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry, 44, 2005
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7D80
| Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase, trigger factor, and methionine aminopeptidase | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Akbar, S, Bhakta, S, Sengupta, J. | Deposit date: | 2020-10-06 | Release date: | 2021-04-07 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into the interplay of protein biogenesis factors with the 70S ribosome. Structure, 29, 2021
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7D6Z
| Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase and trigger factor | Descriptor: | 16S ribosomal rRNA, 23S ribosomal rRNA, 30S ribosomal protein S10, ... | Authors: | Akbar, S, Bhakta, S, Sengupta, J. | Deposit date: | 2020-10-02 | Release date: | 2021-04-07 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the interplay of protein biogenesis factors with the 70S ribosome. Structure, 29, 2021
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3P4L
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6S2W
| Structure of S. pombe Erh1, a protein important for meiotic mRNA decay in mitosis and meiosis progression. | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, ... | Authors: | Hazra, D, Graille, M. | Deposit date: | 2019-06-22 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Formation of S. pombe Erh1 homodimer mediates gametogenic gene silencing and meiosis progression. Sci Rep, 10, 2020
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2A02
| Solution NMR Structure of the Periplasmic Signaling Domain of the Outer Membrane Iron Transporter PupA from Pseudomonas putida. | Descriptor: | Ferric-pseudobactin 358 receptor | Authors: | Ferguson, A.D, Amezcua, C.A, Chelliah, Y, Rosen, M.K, Deisenhofer, J. | Deposit date: | 2005-06-15 | Release date: | 2006-09-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Signal transduction pathway of TonB-dependent transporters. Proc.Natl.Acad.Sci.Usa, 2, 2006
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8G9O
| Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8G9L
| DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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6SAR
| E coli BepA/YfgC | Descriptor: | Beta-barrel assembly-enhancing protease, SULFATE ION, ZINC ION | Authors: | Lovering, A.L, Cadby, I.T. | Deposit date: | 2019-07-17 | Release date: | 2020-08-26 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure-Function Characterization of the Conserved Regulatory Mechanism of the Escherichia coli M48 Metalloprotease BepA. J.Bacteriol., 203, 2020
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7S1G
| wild-type Escherichia coli stalled ribosome with antibiotic linezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2021-11-17 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.48 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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