PDB: 219118 resultsInfo pagesStatus searchChemie searchBIRD

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2CQK	Solution structure of the La domain of c-Mpl binding protein Descriptor: C-Mpl binding protein Authors: Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-20 Release date: 2005-11-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the La domain of c-Mpl binding protein To be Published
9FBX	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5-(1-benzyl-4-chloro-1H-imidazol-2-yl)-1,3-dimethylpyridin-2(1H)-one Descriptor: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 5-(1-benzyl-4-chloro-1H-imidazol-2-yl)-1,3-dimethylpyridin-2(1H)-one, ... Authors: Chung, C. Deposit date: 2024-05-14 Release date: 2024-06-26 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787. J.Med.Chem., 67, 2024
8PR3	Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1 Descriptor: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... Authors: Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. Deposit date: 2023-07-12 Release date: 2024-03-27 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
8PR2	Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI Descriptor: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... Authors: Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. Deposit date: 2023-07-12 Release date: 2024-03-27 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
6SYI	C-TERMINAL DOMAIN OF INFLUENZA POLYMERASE PA SUBUNIT AND OPTIMIZED SMALL PEPTIDE INHIBITOR Descriptor: 1,2-ETHANEDIOL, PB1-11, Polymerase acidic protein, ... Authors: Hejdanek, J, Pachl, P. Deposit date: 2019-09-30 Release date: 2020-11-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Res., 185, 2020
6Z7F	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-(2-(1H-imidazol-4-yl)ethyl)-4-acetamido-3-(benzyloxy)benzamide Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 2, DI(HYDROXYETHYL)ETHER, ... Authors: Chung, C. Deposit date: 2020-05-30 Release date: 2020-07-29 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.605 Å) Cite: Design and Synthesis of a Highly Selective andIn Vivo-Capable Inhibitor of the Second Bromodomain of the Bromodomain and Extra Terminal Domain Family of Proteins. J.Med.Chem., 63, 2020
5CV1	C. elegans PGL-1 Dimerization Domain Descriptor: P granule abnormality protein 1 Authors: Aoki, S.T, Bingman, C.A, Wickens, M, Kimble, J.E. Deposit date: 2015-07-25 Release date: 2016-02-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.599 Å) Cite: PGL germ granule assembly protein is a base-specific, single-stranded RNase. Proc.Natl.Acad.Sci.USA, 113, 2016
4PBO	Crystal structure of zebrafish short-chain pentraxin protein without calcium ions Descriptor: C-reactive protein Authors: Chen, R, Qi, J.X, George, F.G, Xia, C. Deposit date: 2014-04-13 Release date: 2015-03-25 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.701 Å) Cite: Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces. J.Struct.Biol., 189, 2015
5F22	C-terminal domain of SARS-CoV nsp8 complex with nsp7 Descriptor: Non-structural protein, Non-structural protein 7 Authors: Li, S. Deposit date: 2015-12-01 Release date: 2016-01-27 Last modified: 2016-02-03 Method: X-RAY DIFFRACTION (2.155 Å) Cite: C-terminal domain of SARS-CoV nsp8 complex with nsp7 To Be Published
8R07	C-terminal Rel-homology Domain of NFAT1 Descriptor: Nuclear factor of activated T-cells, cytoplasmic 2 Authors: Zak, K.M, Boettcher, J. Deposit date: 2023-10-30 Release date: 2024-03-06 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Ligandability assessment of the C-terminal Rel-homology domain of NFAT1. Arch Pharm, 357, 2024
6E0T	C-terminal domain of Fission Yeast OFD1 Descriptor: Prolyl 3,4-dihydroxylase ofd1 Authors: Bianchet, M.A, Amzel, L.M, Espenshade, P.J, Yeh, T. Deposit date: 2018-07-06 Release date: 2019-09-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.02 Å) Cite: The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor. Structure, 19, 2011
5TD6	C. elegans FOG-3 BTG/Tob domain - H47N, C117A Descriptor: FOG-3 protein, SULFATE ION Authors: Aoki, S.T, Bingman, C.A, Wickens, M, Kimble, J.E. Deposit date: 2016-09-17 Release date: 2017-09-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.034 Å) Cite: An RNA-Binding Multimer Specifies Nematode Sperm Fate. Cell Rep, 23, 2018
5XR1	Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2 Descriptor: C-terminal peptide of Integrin beta-2,Filamin-A IG21 domain Authors: Chatterjee, D, Lu, L.Z, Bhattacharjya, S. Deposit date: 2017-06-07 Release date: 2018-06-13 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2 To Be Published
5XEK	C-terminal zinc finger of RING finger protein 141 Descriptor: RING finger protein 141, ZINC ION Authors: Miyamoto, K. Deposit date: 2017-04-05 Release date: 2018-05-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: C-terminal zinc finger of RING finger protein 141 To Be Published
6M75	C-Myc DNA binding protein complex Descriptor: DNA (5'-D(*TP*CP*TP*TP*AP*TP*T)-3'), RNA-binding motif, single-stranded-interacting protein 1, ... Authors: Aggarwal, P, Bhavesh, N.S. Deposit date: 2020-03-17 Release date: 2021-03-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter. Nucleic Acids Res., 49, 2021
6F1V	C terminal region of the dynein heavy chains in the dynein tail/dynactin/BICDR1 complex Descriptor: Cytoplasmic dynein 1 heavy chain 1 Authors: Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. Deposit date: 2017-11-23 Release date: 2018-01-17 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
7SCA	Synechocystis PCC 6803 Phycobilisome rod from OCP-PBS complex sample Descriptor: C-phycocyanin alpha subunit, C-phycocyanin beta subunit, PHYCOCYANOBILIN, ... Authors: Sauer, P.V, Sutter, M, Dominguez-Martin, M.A, Kirst, H, Kerfeld, C.A. Deposit date: 2021-09-27 Release date: 2022-08-31 Last modified: 2022-10-05 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Structures of a phycobilisome in light-harvesting and photoprotected states. Nature, 609, 2022
7SC8	Synechocystis PCC 6803 Phycobilisome rod from PBS sample Descriptor: C-phycocyanin alpha subunit, C-phycocyanin beta subunit, PHYCOCYANOBILIN, ... Authors: Sauer, P.V, Sutter, M, Dominguez-Martin, M.A, Kirst, H, Kerfeld, C.A. Deposit date: 2021-09-27 Release date: 2022-08-31 Last modified: 2022-10-05 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Structures of a phycobilisome in light-harvesting and photoprotected states. Nature, 609, 2022
7NQ8	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-ethyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-(pyridin-2-ylmethoxy)benzamide Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 2, N-ethyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-(pyridin-2-ylmethoxy)benzamide Authors: Chung, C.W. Deposit date: 2021-03-01 Release date: 2021-03-24 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors. J.Med.Chem., 64, 2021
7NQI	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 2-benzyl-N-cyclopropyl-6-(1-methyl-1H-1,2,3-triazol-4-yl)isonicotinamide Descriptor: 1,2-ETHANEDIOL, 2-benzyl-N-cyclopropyl-6-(1-methyl-1H-1,2,3-triazol-4-yl)isonicotinamide, Bromodomain-containing protein 2 Authors: Chung, C.W. Deposit date: 2021-03-01 Release date: 2021-03-24 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.603 Å) Cite: Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors. J.Med.Chem., 64, 2021
7NQ9	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 2-benzyl-N-cyclopropyl-6-(1-methyl-1H-1,2,3-triazol-4-yl)isonicotinamide Descriptor: 1,2-ETHANEDIOL, 6-benzyl-N4-((1r,3r)-3-hydroxycyclobutyl)-N2-methylpyridine-2,4-dicarboxamide, Bromodomain-containing protein 2 Authors: Chung, C.W. Deposit date: 2021-03-01 Release date: 2021-03-24 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors. J.Med.Chem., 64, 2021
6WIW	c-Src Bound to ATP-Competitive Inhibitor I14 Descriptor: N-(3-{[4-amino-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl}-4-methylphenyl)acetamide, Proto-oncogene tyrosine-protein kinase Src Authors: Vilas-Boas, J, Thakur, M.K, Fang, L, Maly, D, Seeliger, M.A. Deposit date: 2020-04-10 Release date: 2020-06-17 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture. Acs Chem.Biol., 15, 2020
5COW	C. remanei PGL-1 Dimerization Domain Descriptor: 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION Authors: Aoki, S.T, Bingman, C.A, Wickens, M, Kimble, J.E. Deposit date: 2015-07-20 Release date: 2016-02-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: PGL germ granule assembly protein is a base-specific, single-stranded RNase. Proc.Natl.Acad.Sci.USA, 113, 2016
8R3F	C-terminal Rel-homology Domain of NFAT1 Descriptor: (4~{S})-6-fluoranyl-3,4-dihydro-2~{H}-chromen-4-amine, Nuclear factor of activated T-cells, cytoplasmic 2 Authors: Zak, K.M, Boettcher, J. Deposit date: 2023-11-08 Release date: 2024-03-06 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Ligandability assessment of the C-terminal Rel-homology domain of NFAT1. Arch Pharm, 357, 2024
8PX2	C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1,3-dimethyl-5-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one Descriptor: 1,3-dimethyl-5-[1-(oxan-4-ylmethyl)benzimidazol-2-yl]pyridin-2-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bromodomain-containing protein 2 Authors: Chung, C.W. Deposit date: 2023-07-22 Release date: 2023-10-18 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.622 Å) Cite: Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe. J.Med.Chem., 66, 2023

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