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4G3V
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BU of 4g3v by Molmil
Crystal structure of A. Aeolicus nlh2 gaf domain in an inactive state
Descriptor: CHLORIDE ION, Transcriptional regulator nlh2
Authors:Batchelor, J.D, Lee, P, Wang, A, Doucleff, M, Wemmer, D.E.
Deposit date:2012-07-15
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus
J.Mol.Biol., 425, 2013
5DFX
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BU of 5dfx by Molmil
Structure of the parental state of GAF3 from Slr1393 of Synechocystis sp. PCC6803 (in vivo assembled protein/chromophore)
Descriptor: Histidine kinase, PHYCOCYANOBILIN
Authors:Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A.
Deposit date:2015-08-27
Release date:2016-09-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural elements regulating the photochromicity in a cyanobacteriochrome
Proc.Natl.Acad.Sci.USA, 2020
2Y8H
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BU of 2y8h by Molmil
STRUCTURE OF THE FIRST GAF DOMAIN E87G MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS
Descriptor: CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, TWO COMPONENT SENSOR HISTIDINE KINASE DEVS
Authors:Cho, H.Y, Cho, H.J, Kang, B.S.
Deposit date:2011-02-07
Release date:2011-02-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
FEBS Lett., 585, 2011
5DFY
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BU of 5dfy by Molmil
Structure of the parental state of GAF3 from Slr1393 of Synechocystis sp. PCC6803 (in vitro assembled protein/chromophore)
Descriptor: Histidine kinase, PHYCOCYANOBILIN
Authors:Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A.
Deposit date:2015-08-27
Release date:2016-09-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural elements regulating the photochromicity in a cyanobacteriochrome
Proc.Natl.Acad.Sci.USA, 2020
2XSS
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BU of 2xss by Molmil
Crystal structure of GAFb from the human phosphodiesterase 5
Descriptor: CGMP-SPECIFIC 3', 5'-CYCLIC PHOSPHODIESTERASE
Authors:Schlicker, C, Russwurm, M, Steegborn, C.
Deposit date:2010-09-30
Release date:2011-05-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Gaf-B Domain from Human Phosphodiesterase 5.
Proteins, 79, 2011
3K2N
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BU of 3k2n by Molmil
The crystal structure of sigma-54-dependent transcriptional regulator domain from Chlorobium Tepidum TLS
Descriptor: Sigma-54-dependent transcriptional regulator
Authors:Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-30
Release date:2010-01-19
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of sigma-54-dependent transcriptional regulator domain from Chlorobium
To be Published
4FOF
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BU of 4fof by Molmil
Crystal Structure of the blue-light absorbing form of the Thermosynechococcus elongatus PixJ GAF-domain
Descriptor: Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form, ...
Authors:Burgie, E.S, Walker, J.M, Phillips Jr, G.N, Vierstra, R.D.
Deposit date:2012-06-20
Release date:2013-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.416 Å)
Cite:A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes.
Structure, 21, 2013
4G3K
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BU of 4g3k by Molmil
Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state
Descriptor: Transcriptional regulator nlh1
Authors:Wemmer, D.E, Batchelor, J.D, Wang, A, Lee, P, Doucleff, M.
Deposit date:2012-07-14
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus
J.Mol.Biol., 425, 2013
3P01
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BU of 3p01 by Molmil
Crystal structure of two-component response regulator from Nostoc sp. PCC 7120
Descriptor: Two-component response regulator
Authors:Chang, C, Mack, J, Feldman, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-09-27
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of two-component response regulator from Nostoc sp. PCC 7120
TO BE PUBLISHED
8W26
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BU of 8w26 by Molmil
X-ray crystal structure of the GAF-PHY domains of SyB-Cph1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, PHYCOCYANOBILIN, ...
Authors:Burgie, E.S, Vierstra, R.D.
Deposit date:2024-02-20
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Photosensory Module from a PAS-Less Cyanobacterial Phytochrome Reveals a Hybrid Activated Conformation in the Dark-Adapted Pr State
To Be Published
4YOF
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BU of 4yof by Molmil
DosS GAFA Domain Reduced Nitric Oxide Bound Crystal Structure
Descriptor: NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE, Redox sensor histidine kinase response regulator DevS
Authors:Madrona, Y.
Deposit date:2015-03-11
Release date:2016-03-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.
J.Biol.Chem., 290, 2015
3OOV
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BU of 3oov by Molmil
Crystal structure of a methyl-accepting chemotaxis protein, residues 122 to 287
Descriptor: GLYCEROL, Methyl-accepting chemotaxis protein, putative
Authors:Joachimiak, A, Duke, N.E.C, Hatzos-Skintges, C, Mulligan, R, Clancy, S, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-08-31
Release date:2010-09-08
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a methyl-accepting chemotaxis protein, residues 122 to 287
To be Published
2LB5
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BU of 2lb5 by Molmil
Refined Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form
Descriptor: PHYCOCYANOBILIN, Sensor histidine kinase
Authors:Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L.
Deposit date:2011-03-23
Release date:2011-06-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for the photoconversion of a phytochrome to the activated Pfr form.
Nature, 463, 2010
3LFV
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BU of 3lfv by Molmil
crystal structure of unliganded PDE5A GAF domain
Descriptor: cGMP-specific 3',5'-cyclic phosphodiesterase
Authors:Wang, H, Robinson, H, Ke, H.
Deposit date:2010-01-18
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
J.Biol.Chem., 285, 2010
2LB9
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BU of 2lb9 by Molmil
Refined solution structure of a cyanobacterial phytochrome gaf domain in the red light-absorbing ground state (corrected pyrrole ring planarity)
Descriptor: PHYCOCYANOBILIN, Sensor histidine kinase
Authors:Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L.
Deposit date:2011-03-23
Release date:2011-06-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of a cyanobacterial phytochrome GAF domain in the red-light-absorbing ground state.
J.Mol.Biol., 383, 2008
2M7V
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BU of 2m7v by Molmil
Green Light-Absorbing State of TePixJ, an Active Cyanobacteriochrome Domain
Descriptor: Methyl-accepting chemotaxis protein, PHYCOVIOLOBILIN
Authors:Cornilescu, G, Cornilescu, C.C, Burgie, S.E, Walker, J.M, Markley, J.L, Ulijasz, A.T, Vierstra, R.D.
Deposit date:2013-05-01
Release date:2014-01-01
Last modified:2024-03-13
Method:SOLUTION NMR
Cite:Structural and Flexibility Variations Between the Ground and Photoactivated States of a Blue/Green Light-Absorbing Cyanobacteriochrome
To be Published
2M7U
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BU of 2m7u by Molmil
Blue Light-Absorbing State of TePixJ, an Active Cyanobacteriochrome Domain
Descriptor: Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form
Authors:Cornilescu, G, Cornilescu, C.C, Burgie, S.E, Walker, J.M, Markley, J.L, Ulijasz, A.T, Vierstra, R.D.
Deposit date:2013-05-01
Release date:2014-01-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and Flexibility Variations Between the Ground and Photoactivated States of a Blue/Green Light-Absorbing Cyanobacteriochrome
To be Published
6BHN
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BU of 6bhn by Molmil
Red Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Descriptor: Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Yu, Q, Lim, S, Rockwell, N.C, Martin, S.S, Lagarias, J.C, Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3O5Y
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BU of 3o5y by Molmil
The Crystal Structure of the GAF domain of a two-component sensor histidine kinase from Bacillus halodurans to 2.45A
Descriptor: ACETATE ION, Sensor protein
Authors:Stein, A.J, Mack, J, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-07-28
Release date:2010-08-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Crystal Structure of the GAF domain of a two-component sensor histidine kinase from Bacillus halodurans to 2.45A
To be Published
3MF0
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BU of 3mf0 by Molmil
Crystal structure of PDE5A GAF domain (89-518)
Descriptor: cGMP-specific 3',5'-cyclic phosphodiesterase
Authors:Wang, H, Robinson, H, Ke, H.
Deposit date:2010-04-01
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
J.Biol.Chem., 285, 2010
6BHO
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BU of 6bho by Molmil
Green Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Descriptor: Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN
Authors:Lim, S, Yu, Q, Rockwell, N.C, Martin, S.S, Lagarias, J.C, Ames, J.B.
Deposit date:2017-10-31
Release date:2018-04-18
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5M82
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BU of 5m82 by Molmil
Three-dimensional structure of the photoproduct state of GAF3 from Slr1393 of Synechocystis sp. PCC6803
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, PHYCOCYANOBILIN, SODIUM ION, ...
Authors:Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A.
Deposit date:2016-10-28
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural elements regulating the photochromicity in a cyanobacteriochrome
Proc.Natl.Acad.Sci.USA, 2020
5M85
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BU of 5m85 by Molmil
Three-dimensional structure of the intermediate state of GAF3 from Slr1393 of Synechocystis sp. PCC6803
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHYCOCYANOBILIN, ...
Authors:Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A.
Deposit date:2016-10-28
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural elements regulating the photochromicity in a cyanobacteriochrome
Proc.Natl.Acad.Sci.USA, 2020
2W3F
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BU of 2w3f by Molmil
Reduced structure of the first GAF domain of Mycobacterium tuberculosis DosS
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, TWO COMPONENT SENSOR HISTIDINE KINASE DEVS (GAF FAMILY PROTEIN)
Authors:Kang, B.S, Cho, H.Y, Cho, H.J.
Deposit date:2008-11-12
Release date:2009-03-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.
J.Biol.Chem., 284, 2009
2VZW
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BU of 2vzw by Molmil
X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis
Descriptor: ACETATE ION, OXYGEN MOLECULE, PROBABLE HISTIDINE KINASE RESPONSE REGULATOR, ...
Authors:Podust, L.M, Ioanoviciu, A, Ortiz de Montellano, P.R.
Deposit date:2008-08-06
Release date:2009-03-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:2.3 A X-Ray Structure of the Heme-Bound Gaf Domain of Sensory Histidine Kinase Dost of Mycobacterium Tuberculosis.
Biochemistry, 47, 2008

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