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2PT9
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The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA)
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ...
Authors:Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
Deposit date:2007-05-08
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
2PTA
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PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES
Descriptor: PANDINUS TOXIN K-ALPHA
Authors:Tenenholz, T.C, Rogowski, R.S, Collins, J.H, Blaustein, M.P, Weber, D.J.
Deposit date:1996-11-26
Release date:1997-12-10
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.
Biochemistry, 36, 1997
2PTC
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THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
Descriptor: BETA-TRYPSIN, CALCIUM ION, TRYPSIN INHIBITOR
Authors:Huber, R, Deisenhofer, J.
Deposit date:1982-09-27
Release date:1983-01-18
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Geometry of the Reactive Site and of the Peptide Groups in Trypsin, Trypsinogen and its Complexes with Inhibitors
Acta Crystallogr.,Sect.B, 39, 1983
2PTD
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PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D198E
Descriptor: PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Authors:Heinz, D.W.
Deposit date:1997-07-16
Release date:1998-01-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
2PTF
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Crystal structure of protein MTH_863 from Methanobacterium thermoautotrophicum bound to FMN
Descriptor: FLAVIN MONONUCLEOTIDE, Uncharacterized protein MTH_863
Authors:Bonanno, J.B, Rutter, M, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-05-08
Release date:2007-05-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of protein MTH_863 from Methanobacterium thermoautotrophicum bound to FMN.
To be Published
2PTG
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Crystal structure of Eimeria tenella enoyl reductase
Descriptor: Enoyl-acyl carrier reductase
Authors:Lu, J.Z, Prigge, S.T.
Deposit date:2007-05-08
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Type I and type II fatty acid biosynthesis in Eimeria tenella: Enoyl reductase activity and structure
Parasitology, 134, 2007
2PTH
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PEPTIDYL-TRNA HYDROLASE FROM ESCHERICHIA COLI
Descriptor: PEPTIDYL-TRNA HYDROLASE
Authors:Schmitt, E, Mechulam, Y, Fromant, M, Plateau, P, Blanquet, S.
Deposit date:1997-03-25
Release date:1998-03-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure at 1.2 A resolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase.
EMBO J., 16, 1997
2PTK
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BU of 2ptk by Molmil
CHICKEN SRC TYROSINE KINASE
Descriptor: TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC
Authors:Williams, J.C, Wierenga, R.
Deposit date:1997-06-17
Release date:1997-12-24
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions
J.Mol.Biol., 274, 1997
2PTL
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BU of 2ptl by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN-BINDING DOMAIN OF PROTEIN L. COMPARISON WITH THE IGG-BINDING DOMAINS OF PROTEIN G
Descriptor: PROTEIN L
Authors:Wikstroem, M, Drakenberg, T, Forsen, S, Sjoebring, U, Bjoerck, L.
Deposit date:1994-08-12
Release date:1994-10-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G.
Biochemistry, 33, 1994
2PTM
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Structure and rearrangements in the carboxy-terminal region of SpIH channels
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT HEXAMMINE(III), Hyperpolarization-activated (Ih) channel
Authors:Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N.
Deposit date:2007-05-08
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure and rearrangements in the carboxy-terminal region of SpIH channels.
Structure, 15, 2007
2PTN
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ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
Descriptor: CALCIUM ION, TRYPSIN
Authors:Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
Deposit date:1981-10-26
Release date:1982-03-04
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
2PTQ
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BU of 2ptq by Molmil
Crystal structure of Escherichia coli adenylosuccinate lyase mutant H171N with bound AMP and fumarate
Descriptor: ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, FUMARIC ACID
Authors:Tsai, M, Howell, P.L.
Deposit date:2007-05-08
Release date:2007-07-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism.
J.Mol.Biol., 370, 2007
2PTR
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BU of 2ptr by Molmil
Crystal structure of Escherichia coli adenylosuccinate lyase mutant H171A with bound adenylosuccinate substrate
Descriptor: 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, Adenylosuccinate lyase
Authors:Tsai, M, Howell, P.L.
Deposit date:2007-05-08
Release date:2007-07-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism.
J.Mol.Biol., 370, 2007
2PTS
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Crystal structure of wild type Escherichia coli adenylosuccinate lyase
Descriptor: Adenylosuccinate lyase
Authors:Tsai, M, Howell, P.L.
Deposit date:2007-05-08
Release date:2007-07-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism.
J.Mol.Biol., 370, 2007
2PTT
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Structure of NK cell receptor 2B4 (CD244) bound to its ligand CD48
Descriptor: CD48 antigen, Natural killer cell receptor 2B4, SULFATE ION
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTU
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Structure of NK cell receptor 2B4 (CD244)
Descriptor: Natural killer cell receptor 2B4
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTV
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BU of 2ptv by Molmil
Structure of NK cell receptor ligand CD48
Descriptor: CD48 antigen
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTW
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BU of 2ptw by Molmil
Crystal Structure of the T. brucei enolase complexed with sulphate, identification of a metal binding site IV
Descriptor: 1,2-ETHANEDIOL, Enolase, SULFATE ION, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTX
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Crystal Structure of the T. brucei enolase complexed with sulphate in closed conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, SULFATE ION, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTY
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BU of 2pty by Molmil
Crystal Structure of the T. brucei enolase complexed with PEP
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHOENOLPYRUVATE, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PTZ
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Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-out conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU0
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BU of 2pu0 by Molmil
Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-in conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU1
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Crystal Structure of the T. brucei enolase complexed with Fluoro-phosphonoacetohydroxamate (FPAH)
Descriptor: 1,2-ETHANEDIOL, Enolase, ZINC ION, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2PU2
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AmpC beta-lactamase with bound Phthalamide inhibitor
Descriptor: 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID, Beta-lactamase, PHOSPHATE ION
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2007-05-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase.
J.Med.Chem., 51, 2008
2PU3
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Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida
Descriptor: CHLORIDE ION, Endonuclease I, MAGNESIUM ION
Authors:Altermark, B, Helland, R, Moe, E, Willassen, N.P, Smalas, A.O.
Deposit date:2007-05-08
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida.
Acta Crystallogr.,Sect.D, 64, 2008

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