7RLI
| Cryo-EM structure of human p97 bound to CB-5083 and ADP. | Descriptor: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | Deposit date: | 2021-07-23 | Release date: | 2021-09-22 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
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7D4I
| Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
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7D63
| Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-29 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
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7D5T
| Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-28 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) To Be Published
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7D5S
| Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S12, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-28 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) To Be Published
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7ABR
| Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ... | Authors: | Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T. | Deposit date: | 2020-09-08 | Release date: | 2021-10-06 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
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7K56
| Structure of VCP dodecamer purified from H1299 cells | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | Deposit date: | 2020-09-16 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K59
| Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97 | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | Deposit date: | 2020-09-16 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K57
| Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97 | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | Deposit date: | 2020-09-16 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7P6U
| Lon protease from Thermus Thermophilus | Descriptor: | (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK), Lon protease, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Coscia, F, Lowe, J. | Deposit date: | 2021-07-18 | Release date: | 2021-10-27 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the full-length Lon protease from Thermus thermophilus. Febs Lett., 595, 2021
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7FD4
| A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | Deposit date: | 2021-07-16 | Release date: | 2021-11-03 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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7FD5
| A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | Deposit date: | 2021-07-16 | Release date: | 2021-11-03 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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7FID
| Processive cleavage of substrate at individual proteolytic active sites of the Lon proteasecomplex (conformation 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | Deposit date: | 2021-07-31 | Release date: | 2021-11-24 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7FIZ
| Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 3) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | Deposit date: | 2021-08-01 | Release date: | 2021-11-24 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7FIE
| Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | Deposit date: | 2021-07-31 | Release date: | 2021-11-24 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7OXO
| human LonP1, R-state, incubated in AMPPCP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | Authors: | Abrahams, J.P, Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T. | Deposit date: | 2021-06-22 | Release date: | 2021-12-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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7SXO
| Yeast Lon (PIM1) with endogenous substrate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | Authors: | Yang, J, Song, A.S, Wiseman, R.L, Lander, G.C. | Deposit date: | 2021-11-24 | Release date: | 2022-01-12 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of hexameric yeast Lon protease (PIM1) highlights the importance of conserved structural elements. J.Biol.Chem., 298, 2022
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7PX9
| Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state A) | Descriptor: | AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PXA
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7PXC
| Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state A) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PXB
| Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state B) | Descriptor: | AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PXD
| Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state B) | Descriptor: | AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7TIC
| Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | Deposit date: | 2022-01-13 | Release date: | 2022-02-16 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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7TKU
| Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | Deposit date: | 2022-01-17 | Release date: | 2022-02-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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7TI8
| Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | Deposit date: | 2022-01-13 | Release date: | 2022-02-16 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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