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7JR7
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BU of 7jr7 by Molmil
Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4
Descriptor: ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ...
Authors:Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H.
Deposit date:2020-08-11
Release date:2021-04-07
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies
Commun Biol, 4, 2021
7A1G
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BU of 7a1g by Molmil
Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-08-13
Release date:2020-10-14
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
Descriptor: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
Descriptor: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2020-08-25
Release date:2020-10-14
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7K2T
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BU of 7k2t by Molmil
Mg2+/ATP-bound structure of the full-length WzmWzt O antigen ABC transporter in lipid nanodiscs
Descriptor: ABC transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Caffalette, C.A, Zimmer, J.
Deposit date:2020-09-09
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the full-length WzmWzt ABC transporter required for lipid-linked O antigen transport.
Proc.Natl.Acad.Sci.USA, 118, 2021
7D0A
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BU of 7d0a by Molmil
Acinetobacter MlaFEDB complex in ADP-vanadate trapped Vclose conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-DIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D08
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BU of 7d08 by Molmil
Acinetobacter MlaFEDB complex in ATP-bound Vtrans1 conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D09
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BU of 7d09 by Molmil
Acinetobacter MlaFEDB complex in ATP-bound Vtrans2 conformation
Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7D06
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BU of 7d06 by Molmil
Cryo EM structure of the nucleotide free Acinetobacter MlaFEDB complex
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ABC transporter ATP-binding protein, Anti-sigma factor antagonist, ...
Authors:Zhang, Y.Y, Fan, Q.X, Chi, X.M, Zhou, Q, Li, Y.Y.
Deposit date:2020-09-09
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of Acinetobacter baumannii glycerophospholipid transporter.
Cell Discov, 6, 2020
7AHD
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BU of 7ahd by Molmil
OpuA (E190Q) occluded
Descriptor: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHC
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BU of 7ahc by Molmil
OpuA apo inward-facing
Descriptor: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHH
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BU of 7ahh by Molmil
OpuA inhibited inward-facing, SBD docked
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ...
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHE
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BU of 7ahe by Molmil
OpuA inhibited inward facing
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7D7N
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BU of 7d7n by Molmil
Cryo-EM structure of human ABCB6 transporter
Descriptor: ATP-binding cassette sub-family B member 6, mitochondrial
Authors:Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
Deposit date:2020-10-05
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
7D7R
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BU of 7d7r by Molmil
Cryo-EM structure of the core domain of human ABCB6 transporter
Descriptor: ATP-binding cassette sub-family B member 6, mitochondrial
Authors:Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
Deposit date:2020-10-05
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
7ARM
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BU of 7arm by Molmil
LolCDE in complex with lipoprotein and LolA
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARL
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BU of 7arl by Molmil
LolCDE in complex with lipoprotein and ADP
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, ADENOSINE-5'-DIPHOSPHATE, LPP, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARK
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BU of 7ark by Molmil
LolCDE in complex with AMP-PNP in the closed NBD state
Descriptor: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARH
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BU of 7arh by Molmil
LolCDE in complex with lipoprotein
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARJ
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BU of 7arj by Molmil
LolCDE in complex with lipoprotein and AMPPNP complex undimerized form
Descriptor: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARI
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BU of 7ari by Molmil
LolCDE apo structure
Descriptor: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE
Authors:Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
Deposit date:2020-10-25
Release date:2021-04-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7DD0
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BU of 7dd0 by Molmil
Crystal structure of the N-terminal domain of TagH from Bacillus subtilis
Descriptor: Teichoic acids export ATP-binding protein TagH
Authors:Ko, T.P, Yang, C.S, Wang, Y.C, Chen, Y.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the N-terminal domain of TagH reveals a potential drug targeting site.
Biochem.Biophys.Res.Commun., 536, 2020

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