6PSS
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![BU of 6pss by Molmil](/molmil-images/mine/6pss) | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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6PSQ
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![BU of 6psq by Molmil](/molmil-images/mine/6psq) | Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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6PST
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![BU of 6pst by Molmil](/molmil-images/mine/6pst) | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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6WVJ
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![BU of 6wvj by Molmil](/molmil-images/mine/6wvj) | Cryo-EM structure of Bacillus subtilis RNA Polymerase elongation complex | Descriptor: | DNA (5'-D(*TP*GP*TP*CP*GP*GP*GP*CP*GP*TP*CP*CP*GP*CP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*AP*CP*GP*CP*CP*CP*GP*AP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Newing, T, Tolun, G, Oakley, A.J. | Deposit date: | 2020-05-06 | Release date: | 2020-11-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD. Nat Commun, 11, 2020
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6GFW
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![BU of 6gfw by Molmil](/molmil-images/mine/6gfw) | Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Glyde, R, Ye, F.Z, Zhang, X.D. | Deposit date: | 2018-05-02 | Release date: | 2018-07-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70, 2018
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6PSV
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![BU of 6psv by Molmil](/molmil-images/mine/6psv) | Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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5NWT
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![BU of 5nwt by Molmil](/molmil-images/mine/5nwt) | Crystal Structure of Escherichia coli RNA polymerase - Sigma54 Holoenzyme complex | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhang, X, Buck, M, Darbari, V.C, Yang, Y, Zhang, N, Lu, D, Glyde, R, Wang, Y, Winkelman, J, Gourse, R.L, Murakami, K.S. | Deposit date: | 2017-05-08 | Release date: | 2017-09-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.76 Å) | Cite: | TRANSCRIPTION. Structures of the RNA polymerase-Sigma54 reveal new and conserved regulatory strategies. Science, 349, 2015
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7Z43
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![BU of 7z43 by Molmil](/molmil-images/mine/7z43) | |
7Z42
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![BU of 7z42 by Molmil](/molmil-images/mine/7z42) | |
8RBO
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![BU of 8rbo by Molmil](/molmil-images/mine/8rbo) | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation | Descriptor: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | Authors: | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | Deposit date: | 2023-12-04 | Release date: | 2024-04-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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7OGP
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![BU of 7ogp by Molmil](/molmil-images/mine/7ogp) | Structure of the apo-state of the bacteriophage PhiKZ non-virion RNA polymerase - class including clamp | Descriptor: | DNA-directed RNA polymerase, PHIKZ055, PHIKZ068, ... | Authors: | de Martin Garrido, N, Lai Wan Loong, Y.T.E, Yakunina, M, Aylett, C.H.S. | Deposit date: | 2021-05-07 | Release date: | 2021-07-07 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the bacteriophage PhiKZ non-virion RNA polymerase. Nucleic Acids Res., 49, 2021
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6P70
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![BU of 6p70 by Molmil](/molmil-images/mine/6p70) | X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex | Descriptor: | DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Shin, Y, Murakami, K.S. | Deposit date: | 2019-06-04 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
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8ORQ
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![BU of 8orq by Molmil](/molmil-images/mine/8orq) | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase open clamp conformation | Descriptor: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | Authors: | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | Deposit date: | 2023-04-17 | Release date: | 2024-04-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52, 2024
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8DH4
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![BU of 8dh4 by Molmil](/molmil-images/mine/8dh4) | T7 RNA polymerase elongation complex with unnatural base dPa-DsTP pair | Descriptor: | (7P)-3-{5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-7-(thiophen-2-yl)-3H-imidazo[4,5-b]pyridine, MAGNESIUM ION, Non-template strand DNA, ... | Authors: | Oh, J, Wang, D. | Deposit date: | 2022-06-24 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase. Nat Commun, 14, 2023
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8DH3
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![BU of 8dh3 by Molmil](/molmil-images/mine/8dh3) | T7 RNA polymerase elongation complex with unnatural base dPa | Descriptor: | Non-template strand DNA, RNA, T7 RNA polymerase, ... | Authors: | Oh, J, Wang, D. | Deposit date: | 2022-06-24 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase. Nat Commun, 14, 2023
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8DH1
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![BU of 8dh1 by Molmil](/molmil-images/mine/8dh1) | T7 RNA polymerase elongation complex with unnatural base dDs-PaTP pair | Descriptor: | 1-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-1H-pyrrole-2-carbaldehyde, GLYCEROL, MAGNESIUM ION, ... | Authors: | Oh, J, Wang, D. | Deposit date: | 2022-06-24 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase. Nat Commun, 14, 2023
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8DH0
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![BU of 8dh0 by Molmil](/molmil-images/mine/8dh0) | T7 RNA polymerase elongation complex with unnatural base dDs | Descriptor: | GLYCEROL, Non-template strand DNA, RNA, ... | Authors: | Oh, J, Wang, D. | Deposit date: | 2022-06-24 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase. Nat Commun, 14, 2023
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8DH2
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![BU of 8dh2 by Molmil](/molmil-images/mine/8dh2) | |
8DH5
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![BU of 8dh5 by Molmil](/molmil-images/mine/8dh5) | |
7Z4O
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![BU of 7z4o by Molmil](/molmil-images/mine/7z4o) | |
7S01
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![BU of 7s01 by Molmil](/molmil-images/mine/7s01) | X-ray structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with a forked oligonucleotide containing the P077 promoter | Descriptor: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | Authors: | Leiman, P.G, Sokolova, M.L, Gordeeva, J, Fraser, A, Severinov, K.V. | Deposit date: | 2021-08-28 | Release date: | 2022-07-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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8URW
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![BU of 8urw by Molmil](/molmil-images/mine/8urw) | Cyanobacterial RNA polymerase elongation complex with NusG and CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (40-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Qayyum, M.Z, Imashimizu, M, Leanca, M, Vishwakarma, R.K, Bradley Riaz, A, Yuzenkova, Y, Murakami, K.S. | Deposit date: | 2023-10-26 | Release date: | 2023-12-27 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
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7AST
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![BU of 7ast by Molmil](/molmil-images/mine/7ast) | Apo Human RNA Polymerase III | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A. | Deposit date: | 2020-10-28 | Release date: | 2020-12-23 | Last modified: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of human RNA polymerase III. Nat Commun, 11, 2020
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7UM0
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![BU of 7um0 by Molmil](/molmil-images/mine/7um0) | Structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with two DNA oligonucleotides containing the AR9 P077 promoter as determined by cryo-EM | Descriptor: | DNA (5'-D(P*GP*UP*U)-3'), DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, ... | Authors: | Leiman, P.G, Fraser, A, Sokolova, M.L. | Deposit date: | 2022-04-05 | Release date: | 2022-07-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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7UM1
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![BU of 7um1 by Molmil](/molmil-images/mine/7um1) | Structure of bacteriophage AR9 non-virion RNAP polymerase holoenzyme determined by cryo-EM | Descriptor: | DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ... | Authors: | Leiman, P.G, Fraser, A, Sokolova, M.L. | Deposit date: | 2022-04-05 | Release date: | 2022-07-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase. Nat Commun, 13, 2022
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